SavedAdd your journal

Journals / Glokom Katarakt / 2019 / Cilt: 14 - Sayı: 1

The Effect of Selective Laser Trabeculoplasty on Intraocular Pressure, Central Corneal Thickness and Corneal Endothelial Cell Analysis in Open Angle Glaucoma

Açık Açılı Glokomda Selektif Lazer Trabeküloplastinin Göz İçi Basıncı, Santral Kornea Kalınlığı ve Kornea Endotel Hücre Analizi Üzerine Etkisi

ÖMER KARTI
Tümay ÖZÇAM
Bora YÜKSEL
TUNCAY KÜSBECİ
Pages
42–46
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Further studies are necessary to confi rm our fi ndings.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Purpose: To investigate the short term effects of selective laser trabeculoplasty (SLT) on the intraocular pressure (IOP), central corneal thickness (CCT) and corneal endothelial cell analysis.
📊
Key Findings & Data:Materials and Methods: Thirty eyes of 30 primary open angle glaucoma (OAG) patients were included in this study.
💡
Conclusion & Impact:Further studies are necessary to confi rm our fi ndings.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To investigate the short term effects of selective laser trabeculoplasty (SLT) on the intraocular pressure (IOP), central corneal thickness (CCT) and corneal endothelial cell analysis. Materials and Methods: Thirty eyes of 30 primary open angle glaucoma (OAG) patients were included in this study. SLT was performed on all patients at 360 degrees of trabecular meshwork. Corneal endothelial cell analysis, CCT and IOP measurements were performed at baseline before SLT as well as 1 week and 1 month after SLT. Results: Thirteen of 30 patients were male (43.3%) and 17 were female (56.7%). The mean age of the patients was 70.03 ± 8.4 years. Although IOP increased at the fi rst hour following SLT, a statistically signifi cant decrease occurred during follow-up (p 0.05). Although a slight increase in CCT was observed during follow-up, the difference between pre-and post- SLT values was not statistically signifi cant (p>0.05). Conclusions: This study demonstrated that SLT provides a signifi cant decrease in IOP at the 1 st week and 1 st month after the procedure. Also, no harmful effect was observed on endothelial cell function and CCT. Further studies are necessary to confi rm our fi ndings.

Özet

Amaç: Selektif lazer trabeküloplasti (SLT) 'nin göz içi basıncı (GİB), santral kornea kalınlığı (SKK) ve kornea endotel hücre analizi üzerine olan kısa dönem etkilerini araştırmak. Gereç ve Yöntem: Otuz primer açık açılı glokom hastasının 30 gözü çalışmaya dahil edildi. SLT tüm hastalarda 360 derecelik trabeküler ağa uygulandı. Korneal endotel hücre analizi, SKK ve GİB ölçümleri SLT öncesi yanısıra SLT’den1 hafta ve 1 ay sonra yapıldı. Bulgular: Otuz hastanın 13’ü erkek (%43.3), 17’si kadın idi (%56.7). Hastaların yaş ortalaması 70.03 ± 8.4 yıl idi. SLT sonrası 1.saatte GİB artmış olmasına rağmen, izlem sırasında GİB’de istatistiksel olarak anlamlı azalma vardı (p 0.05). Takip süresince SKK'da hafi f bir artış olmasına rağmen, SLT öncesi ve sonrası değerler arasındaki fark istatistiksel olarak anlamlı değildi (p>0.05). Sonuç: Bu çalışma; SLT'nin 1. hafta ve 1. ayda göz içi basıncında belirgin bir düşüş sağladığını göstermektedir. Ayrıca, SLT’nin kornea endotel hücre işlevleri ve SKK üzerine olumsuz bir etkisi gözlenmemiştir. Bulgularımızı doğrulamak için başka çalışmalara ihtiyaç vardır.

🔖

Cite This Article

KARTI, Ö., ÖZÇAM, T., YÜKSEL, B., KÜSBECİ, T. (2019). The Effect of Selective Laser Trabeculoplasty on Intraocular Pressure, Central Corneal Thickness and Corneal Endothelial Cell Analysis in Open Angle Glaucoma. Glokom Katarakt, Cilt: 14 - Sayı: 1, 42–46. https://ajindex.com/articles/160450

References (13)

  1. Latina MA, Tumbocon JA. Selective laser trabeculoplasty: a new treatment option for open angle glaucoma. Curr Opin Ophthalmol. 2002;13:94–96.
  2. Shi JM, Jia SB. Selective laser trabeculoplasty. Int J Ophthalmol. 2012;5:742–749.
  3. McIlraith I, Strasfeld M, Colev G, Hutnik CM. Selective laser trabeculoplasty as initial and adjunctive treatment for open-angle glaucoma. J Glaucoma. 2006;15:124–130.
  4. Latina MA, Park C. Selective targeting of trabecular meshwork cells; in vitro studies of pulsed and CW laser interactions. Exp Eye Res. 1995;60:359–371.
  5. Latina MA, Gulati V. Selective laser trabeculoplasty: stimulating the meshwork to mend its ways. Int Ophthalmol Clin. 2004;44(1):93–103.
  6. Goyal S, Beltran-Agullo L, Rashid S, et al. Effect of primary selective laser trabeculoplasty on tonographic outfl ow facility: a randomised clinical trial. Br J Ophthalmol. 2010;94:1443–1447.
  7. Beltran-Agullo L, Alaghband P, Obi A, et al. The effect of selective laser trabeculoplasty on aqueous humor dynamics in patients with ocular hypertension and primary open-angle glaucoma. J Glaucoma. 2012;22:746–749.
  8. Latina MA, Sibayan SA, Shin DH, et al. Q-switched 532-nm Nd:YAG laser trabeculoplasty (selective laser trabeculoplasty): a multicenter, pilot, clinical study. Ophthalmology 1998;105:2089– 2090. Song J. Complications of selective laser trabeculoplasty: a review. Clin Ophthalmol. 2016;10:137-43.
  9. Melamed S, Ben Simon GJ, Levkovitch-Verbin H. Selective laser trabeculoplasty as primary treatment for open-angle glaucoma: a prospective, nonrandomized pilot study. Arch Ophthalmol. 2003;121:957–960. Mahdy MA. Effi cacy and safety of selective laser trabeculoplasty as a primary procedure for controlling intraocular pressure in primary open angle glaucoma and ocular hypertensive patients. Sultan Qaboos Univ Med J. 2008;8:53–58.
  10. Shazly TA, Smith J, Latina MA. Long-term safety and effi cacy of selective laser trabeculoplasty as primary therapy for the treatment of pseudoexfoliation glaucoma compared with primary open- angle glaucoma. Clin Ophthalmol. 2010;5:5–10
  11. Lee JW, Chan JC, Chang RT, et al. Corneal changes after a single session of selective laser trabeculoplasty for open-angle glaucoma. Eye (Lond). 2014;28:47–52.
  12. Wood SD, Elam A, Moroi S. Rare corneal complication following selective laser trabeculoplasty. Am J Ophthalmol Case Rep. 2018;10:28-31.
  13. Alvarado JA, Iguchi R, Martinez J, et al. Similar effects of selective laser trabeculoplasty and prostaglandin analogs on the permeability of cultur