We are reporting a anti-PLA2R negative 65 years old female nephrotic sydrome patient who was diagnosed with pancreatic cancer while being scanned for maligencies.
📌 3 Key Takeaways
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Objective & Hypothesis:In Patients with newly diagnosed Membranous Nephropathy in advanced age with the absence of Anti-PLA2R antibodies in their circulation, must be evaluated thoroughly for occult malignancy.
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Key Findings & Data:In Patients with newly diagnosed Membranous Nephropathy in advanced age with the absence of Anti-PLA2R antibodies in their circulation, must be evaluated thoroughly for occult malignancy.
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Conclusion & Impact:We are reporting a anti-PLA2R negative 65 years old female nephrotic sydrome patient who was diagnosed with pancreatic cancer while being scanned for maligencies.
In Patients with newly diagnosed Membranous Nephropathy in advanced age with the absence of Anti-PLA2R antibodies in their circulation, must be evaluated thoroughly for occult malignancy. We are reporting a anti-PLA2R negative 65 years old female nephrotic sydrome patient who was diagnosed with pancreatic cancer while being scanned for maligencies.
Özet
İdiyopatik Membranöz Nefropatide dolaşımda tesbit edilen anti-PLA2R otoantikorları saptanmayan yeni tanı almış Membranöz Nefropatili ileri yaş hastalarda okkult malignite ısrarla aranmalıdır. Biz Anti-PLA 2R negatif,65 yaşındaki nefrotik sendromlu bayan hastada malignite taramasıyla tesbit ettiğimiz pankreas kanseri vakasını bildiriyoruz
Kılıç, B., Özalp, B., Önder, E. C., Tıraş, H., Aktacir, İ., Özkurt, S. (2019). Pancreatic Cancer in an Elderly with Anti-PLA 2R Negative Membranous Nephropathy: Case Report. Türk Tıp Öğrencileri Araştırma Dergisi, Cilt: 1 Sayı: 1, 24–26. https://ajindex.com/articles/1603448
Swaminathan S, Leung N, Lager DJ, Melton LJ 3rd, Bergstralh EJ, Rohlinger A, Fervenza FC: Changing incidence of glomerular disease in OlmstedCounty, Minnesota: a 30-year renal biopsy study. Clin J Am SocNephrol 2006; 1: 483-487.
Ponticelli C, Glassock RJ: Glomerular diseases: membranous nephropathy - a modern view. Clin J Am Soc Nephrol 2014;9:609-616.
Lee JC, Yamauchi H, Hopper J Jr: Theassociation of cancer and the nephrotic syndrome. Ann Intern Med 1966;64:41-51.
Leeaphorn N, Kue-A-Pai P, Thamcharoen N, Ungprasert P, Stokes MB, Knight EL. Prevalence of cancer in membranous nephropathy: a systematic review and meta-analysis of observational studies. Am J Nephrol. 2014;40(1):29-35. doi: 10.1159/0003 64782.
Lefaucheur C, Stengel B, Nochy D, Martel P, Hill GS, Jacquot C, Rossert J, GN-PROGRESS StudyGroup: Membranous nephropathy and cancer: epidemiologic evidence and determinants of high-risk cancer association. KidneyInt 2006;70:1510-1517.