AI Summary & Key Takeaways
AI InsightIn Conclusiuon, NACT may be an alternative to current traetment modalities for locally advanced cervical cancer especially in developing countries.
📌 3 Key Takeaways
Abstract
In early stage cervical cancer that up to stage IB1 disease and some stage IIA cancers, treatment options include surgery, radiation therapy, or both depending on the preference of the physician and patient. Treatmet of locally advanced (Stage Ib2, bulky IIA, IIb,III and IVA) cervical cancers is controversial and have no any standardization. Current treatment strategies includes primary chemoradiation, NACT, followed by radical hysterectomy and subsequent chemoradiation as indicated, and in very selected cases, primary radical hysterectomy and lymphadenectomy followed by tailored radiotherapy with concomitant chemotherapy. It was reviewed studies of primary neoadjuvant chemotherapy (NACT) followed by radical hysterectomy in this study. In Conclusiuon, NACT may be an alternative to current traetment modalities for locally advanced cervical cancer especially in developing countries.
Özet
Evre Ib1'e kadar olan erken evre ve bazı evre IIa serviks kanserlerinin tedavisinde cerrahi, radyoterapi veya her ikisi hasta ve hekim tercihine göre uygulanabilirken lokal ileri evre (Stage Ib2, bulky IIA, IIb,III and IVA) kanserleri tedavisi tartışmalı olup herhangi bir standardizasyona sahip değildir. Güncel tedaviler primer kemoradyoterapi, NACT+radikal cerrahi ve endike olduğunda kemoradyoterapi ve seçilmiş vakalarda primer radikal histerektomi+lenfadenektomi+ özelleştirilmiş kemoradyoterapi uygulamalarıdır. Bu çalışmada cerrahi öncesi NACT uygulaması yapılan çalışmaların derlemesi yapılmıştır. Sonuç olarak, NAKT lokal ileri evre hastalığın tedavisinde özellikle gelişmekte olan ülkelerde kemoradyoterapiye bir alternatif olabilir.