SavedAdd your journal

Journals / Journal of Pharmaceutical Technology / 2026 / Volume: 1 Issue: 1

Evaluation of the effect of anti-pollution & anti-aging eye cream on the collagen contraction

Gülşah Gedik(TRAKYA UNIVERSITY)0000-0003-4147-6729
Seda Alaca(Tan- Alize Kozmetik A.Ş.)0000-0002-9433-7055
Pages
—
Publication Date
2020-04-01
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

According to the results obtained under the conditions of the test, the eye cream tends to increase the collagen contraction and a significative decrease of the lattice surface by 6.68% compared to the control at 16 hours.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:This is a study of the brown algae-derived hydrolyzed algin as used in eye cream formulation.
📊
Key Findings & Data:Therefore, cutaneous sagging is frequently seen to appear around 40 years of age, very often aggravated by environmental factors such as pollution.
💡
Conclusion & Impact:According to the results obtained under the conditions of the test, the eye cream tends to increase the collagen contraction and a significative decrease of the lattice surface by 6.68% compared to the control at 16 hours.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Anti-Aging · Anti-Pollution · Collagen

Abstract

This is a study of the brown algae-derived hydrolyzed algin as used in eye cream formulation. Alginic acid sodium is a gelling and non-toxic anionic polysaccharide, which is used to bone tissue engineering, preparation of alginate hydrogels, encapsulating, hydrating, protective, and de-polluting action. The skin of eye contour is thinner and less dense in support fibres than other parts of the face. Therefore, cutaneous sagging is frequently seen to appear around 40 years of age, very often aggravated by environmental factors such as pollution. The objective of the study was to evaluate the effect of anti-pollution & anti-aging eye cream on the collagen contraction. The outcomes of the characterization analysis indicate the development of successful cream formulation with optimum characteristics. No microbial growth was observed. The collagen lattices were prepared with human dermal fibroblasts, for evaluation of the effect of the cream on the collagen contraction. The lattices were treated or not (control) with the tested cream and then incubated at 37°C for 96 hours. The surface of lattices was measured by image analysis, and the lattices contraction was analyzed at 16, 24, 40, 48, 64, 72, 88, and 96 hours (the measure of lattices area). The treatment with eye cream at 0.5% decreases the surface of the lattice compared to the control (no treatment). According to the results obtained under the conditions of the test, the eye cream tends to increase the collagen contraction and a significative decrease of the lattice surface by 6.68% compared to the control at 16 hours.

🔖

Cite This Article

Gedik, G., Alaca, S. (2020). Evaluation of the effect of anti-pollution & anti-aging eye cream on the collagen contraction. Journal of Pharmaceutical Technology, Volume: 1 Issue: 1. https://doi.org/10.37662/jpt.2020.2

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (26)

  1. Becker L., Safety assessment of brown algae-derived ingredients as used in cosmetics. Draft Report for Panel Review. (2018); 21-22
  2. Bhutia TK, Petruzzello M, Pallardy R, Rimsa C. Brown Algae. Encyclopaedia Britannica. (2018). Retrieved October 3, 2018 from https://www.britannica.com/science/brownalgae
  3. Becker LC, Bergfeld WF, Belsito DV. Safety assessment of phytosterols as used in cosmetics. Washington, DC: Cosmetic Ingredient Review (CIR). (2014). Retrieved July 23, 2018 from http://online.personalcarecouncil.org/ctfa-static/online/lists/cirpdfs/ FR651.pdf
  4. Johnson Jr WJ, Heldreth B, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks Jr JG, Shank RC, Slaga TJ, Snyder PW, Gill LJ. Safety assessment of polysaccharide gums as used in cosmetics. Washington, DC: Cosmetic Ingredient Review (CIR). (2015). Retrieved July 23, 2018 from https://www.cir-safety.org/ingredients
  5. Teegarden DM. Polymer Chemistry: Introduction to an indispensable science. National Science Teachers Association. Virginia: NSTA Press; (2004). 286 p. ISBN:9-780-8735-5221-9
  6. Zhensheng L, Hassna R, Kip DH, Demin X, Miqin Z. Chitosan- alginate hybrid scaffolds for bone tissue engineering. Biomaterials. (2005); 26(18): 3919-3928. https://doi.org/10.1016/j.biomaterials.2004.09.062
  7. Broderick E, Lyons H, Pembroke T, Byrne H, Murray B, Hall M. The characterisation of a novel, covalently modified, amphiphilic alginate derivative, which retains gelling and non-toxic properties. J Coll int Science. (2006); 298(1): 154-161. https://doi.org/10.1016/j.jcis.2005.12.026
  8. Hu M, Li y, Decker EA, McClements DJ. Role of calcium and calcium-binding agents on the lipase digestibility of emulsified lipids using an in vitro digestion model. Food Hydrocoll. (2010); 24(8), 719-772. https://doi.org/10.1016/j.foodhyd.2010.03.010
  9. Vu TT, Carine Lim C, Lim M. Characterization of leukemic cell behaviors in a soft marrow mimetic alginate hydrogel. J Biomed Mater Res B. (2012); 100(7): 1980-1988. https://doi.org/10.1002/jbm.b.32765
  10. Estevinho BN, Damas AM, Martins P, RochaF. Microencapsulation of β-galactosidase with different biopolymers by a spray-drying process. Food Res Int. (2014); 64, 134-140. https://doi.org/10.1016/j.foodres.2014.05.057
  11. McHugh DJ. A guide to the seaweed industry. Rome: FAO; (2003). 118 p. ISBN:92-5-104958-0
  12. Davis TA, Volesky B, Mucci A. A review of the biochemistry of heavy metal biosoption by brown algae. Water Res. (2003); 37(18): 4311-4330. https://doi.org/10.1016/S0043-1354(03)00293-8
  13. Besada V, Andrade J, Schultze F, Gonzales JJ. Heavy metals in edible seaweeds commercialised for human consumption. J Mar Sys. (2018); 75(1-2): 305-313. https://doi.org/10.1016/j.jmarsys.2008.10.010
  14. Cityguard (2018); Retrieved May 05, 2020 from http://www.codiftn.com/en/principesactifs
  15. English JSC, Dawe RS, Ferguson J. Environmental effects and skin disease. Br Med Bull. (2003); 68 (1):129-142. https://doi.org/10.1093/bmb/ldg026
  16. Jo JH, Kennedy EA, Kong HH. Topographical and physiological differences of the skin mycobiome in health and disease. Virulence. (2017); 8(3): 324-333. https://doi.org/10.1080/21505594.2016.1249093
  17. Mancebo SE, Wang SQ. Recognizing the impact of ambient air pollution on skin health. J Eur Acad Dermatol Venereol. (2015); 29 (12): 2326-2332. https://doi.org/10.1111/jdv.13250
  18. Rembiesa J, Ruzgas T, Engblom J, Holefors A. The impact of pollution on skin and proper efficacy testing for anti-pollution claims. Cosmetics. (2018); 5(1):4. https://doi.org/10.3390/cosmetics5010004
  19. Vierkötter A, Schikowski T, Ranft U, Sugiri D, Matsui M, Krämer U, Krutmann J. Airborne particle exposure and extrinsic skin aging. J Invest Derm. (2010); 130(12): 2719-2726. https://doi.org/10.1038/jid.2010.204
  20. Li M, Vierkötter A, Schikowski T, Hüls A, Ding A, Matsui MS, Deng B, Ma C, Ren A, Zhang J, Tan J9, Yang Y, Jin L, Krutmann J, Li Z, Wang S. Epidemiological evidence that indoor air pollution from cooking with solid fuels accelerates skin aging in Chinese women. J Derm Sci. (2015); 79(2): 148-154. https://doi.org/10.1016/j.jdermsci.2015.04.001
  21. Hüls A, Vierkötter A, Gao W, Krämer U, Yang Y, Ding A, Stolz S, Matsui M, Kan H, Wang S, Jin L, Krutmann J, Schikowski T. Traffic- related air pollution contributes to development of facial lentigines: further epidemiological evidence from Caucasians and Asians. J Invest Derm. (2016); 136(5): 1053-1056. https://doi.org/10.1016/j.jid.2015.12.045
  22. Ding A, Yang Y, Zhao Z, Hüls A, Vierkötter A, Yuan Z, Cai J, Zhang J, Gao W, Li J, Zhang M, Matsui M, Krutmann J, Kan H, Schikowski T, Jin L, Wang S. Indoor PM2.5 exposure afects skin aging manifestation in a Chinese population. Sci Rep. (2017); 7: 15329. https://doi.org/10.1038/s41598-017-15295-8
  23. Li N, Sioutas C, Cho A, Schmitz D, Misra C, Sempf J, Wang M, Oberley T, Froines J, Nel A. Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage. Env Health Perspect. (2003); 111(4):455-460. https://doi.org/10.1289/ehp.6000
  24. Fernando IPS, Jayawardena TU, Sanjeewa KKA, Wang L, Jeon YJ, Lee WW. Anti-inflammatory potential of alginic acid from Sargassum horneri against urban aerosol-induced inflammatory responses in keratinocytes and macrophages. Ecotoxicol Environ Saf. (2018); 160:24-31. https://doi.org/10.1016/j.ecoenv.2018.05.024
  25. Schulze C, Wetzel F, Kueper T, Anke Malsen A, Muhr G, Jaspers S, Blatt T, Wittern KP, Wenck H, Käs JA. Stiffening of human skin fibroblasts with age. Biophys J. (2010); 99(8): 2434-2442. https://doi.org/10.1016/j.bpj.2010.08.026
  26. Park RM, Ji Ahn JY, Kim SY, Wee JH, Kim YH, Jiho Min J. Effect of alginate oligosaccharides on collagen expression in HS 27 human dermal fibroblasts. J Toxicol Environ Health Sci. (2019); 11: 327-334. https://doi.org/10.1007/s13530-019-0421-5