Journals / International Econometric Review / 2026 / Volume: 17 Issue: 2

Analysis of the Relationship between R&D and Pharmaceutical Foreign Trade: A Macro and Micro Data Analysis

Pages
—
Publication Date
2026-02-23
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The results indicate that pharmaceutical R&D expenditures positively affect pharmaceutical exports in the long run, while they negatively affect pharmaceutical imports.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The study examines the impact of pharmaceutical R&D expenditures on pharmaceutical foreign trade by utilizing macro and microdata.
📊
Key Findings & Data:The macro data is sourced from open-access databases provided by OECD and TURKSTAT, while the microdata analysis was conducted at the TURKSTAT data research center.
💡
Conclusion & Impact:The results indicate that pharmaceutical R&D expenditures positively affect pharmaceutical exports in the long run, while they negatively affect pharmaceutical imports.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Pharmaceutical R&D Expenditures · Pharmaceutical Trade · Health Economics

Abstract

The study examines the impact of pharmaceutical R&D expenditures on pharmaceutical foreign trade by utilizing macro and microdata. The macro data is sourced from open-access databases provided by OECD and TURKSTAT, while the microdata analysis was conducted at the TURKSTAT data research center. The macro-level data analysis involves a cointegration test followed by estimating long-term coefficients. The results indicate that pharmaceutical R&D expenditures positively affect pharmaceutical exports in the long run, while they negatively affect pharmaceutical imports. In addition, pharmaceutical R&D expenditures positively affect total exports but not total imports. The micro-level data analysis involves POLS, fixed and random effect panel models. The findings reveal that pharmaceutical firm’s R&D expenditure is positively correlated with exports and negatively correlated with imports. The macro and micro data findings align with our expectations, reinforcing each other intensely.

🔖

Cite This Article

Akpınar, A., Abay, M., Tosunoğlu, M., Kılıç, B., Akgüngör, S. (2026). Analysis of the Relationship between R&D and Pharmaceutical Foreign Trade: A Macro and Micro Data Analysis. International Econometric Review, Volume: 17 Issue: 2. https://doi.org/10.33818/ier.1731218

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (33)

  1. Akpınar, A. and N. Çelik (2025). OECD Ülkelerinde Cari Açık Sorunu ve Çözüm Önerileri: DFE-ARDL Panel Model Bulguları. Dokuz Eylül Üniversitesi İşletme Fakültesi Dergisi, 26(1), 46-66.
  2. Boydak, H. and M. Polat (2022). ARGE Yatırımlarının Dış Ticarete Etkisi: ARDL Yaklaşımıyla Türkiye Örneği. Yüzüncü Yıl Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, (56), 28-49.
  3. Bravo-Ortega, C., & Marín, Á. G. (2011). R&D and productivity: A two way avenue?. World Development, 39(7), 1090-1107.
  4. Cassiman, B., & Martinez-Ros, E. (2007). Product innovation and exports. Evidence from Spanish manufacturing, IESE Business School, Barcelona, (1-36).
  5. Dam, M. M., and Ş. Bulut (2015). Ar-Ge yatırımlarının dış ticaret performansına etkisi: OECD ülkeleri için ampirik bir analiz. In EconAnadolu Conference.
  6. Fagerberg, J. (1988). International competitiveness. The economic journal, 98(391), 355-374. Golovko, E., & Valentini, G. (2011). Exploring the complementarity between innovation and export for SMEs’ growth. Journal of international business Studies, 42(3), 362-380.
  7. Goldar, B. (2013). R&D intensity and exports: A study of Indian pharmaceutical firms. Innovation and Development, 3(2), 151-167.
  8. Göçer, İ. (2013). ARGE Harcamalarının Yüksek Teknolojili Ürün İhracatı, Dış Ticaret Dengesi ve Ekonomik Büyüme Üzerindeki Etkileri. Maliye Dergisi, 165(2), 215-240.
  9. Keller, W. (2004). International technology diffusion. Journal of economic literature, 42(3), 752-782.
  10. Nandy, S. and F. Sussan (2021). R&D Intensity and Export: The Case of Indian Pharmaceutical Industry. Review of Integrative Business and Economics Research, 10, 1-16.
  11. OECD. (2025). Research and development statistics. OECD. Retrieved August 13, 2025, from https://www.oecd.org/en/data/datasets/research-and-development-statistics.html
  12. Özer, M. and N. Çiftçi (2009). Ar-Ge harcamaları ve ihracat ilişkisi: OECD ülkeleri panel veri analizi. Dumlupınar Üniversitesi Sosyal Bilimler Dergisi, 23(3), 39-50.
  13. Pesaran, M. H., Y. Shin and R. J. Smith (2001). Bounds testing approaches to the analysis of level relationships. Journal of Applied Econometrics, 16(3), 289-326.
  14. Polat, A., M., (2018). Ar&Ge ve İnovasyonun Ülkelerin İhracat Performansına Etkileri: Gelişmekte Olan Asya Ülkeleri İçin Yeni Nesil Bir Panel Veri Analizi, Gaziantep University Journal of Social Sciences, 17 (3), 997- 1015, Submission Date: 16-04-2018, Acceptance Date: 09-07-2018.
  15. Ricardo, D., (1817). On The Principles of Political Economy and Taxation. John Murray, 1821, 3th Edt. Michigan University.
  16. Romer, P.M., (1990). “Endogenous technological change”. Journal Of Political Economy. 98, 71–102.
  17. Romer, P. M. (1986). “Increasing Returns And Long-Run Growth”. Journal Of Political Economy, 94(5), 1002-1037.
  18. Rud, I., M. Vancauteren, H. W. Van Roekel and M. Polder (2023). The Relationship Between R&D and Exports in Goods and Services of Firms in the Netherlands: An Empirical Analysis. Journal of Industry, Competition and Trade, 23(3), 283-308.
  19. Schumpeter, J.A. (1934) The Theory of Economic Development, Harvard University Press: Cambridge MA.
  20. Schumpeter, J.A. (1943) Capitalism, Socialism and Democracy, London: George Allen and Unwin.
  21. Smith, A., (1776). An Inquiry into the Nature and Causes of the Wealth of Nations, Methuen & Co, London 1904 5th.
  22. Solow, R.M., (1956). “A Contribution to the Theory of Economic Growth”. Quarterly Journal Of Economics. 70, 65–94.
  23. Sözen, M., and M. Şengür (2023). ARGE Harcamalarının İhracat, İthalat ve Yoksulluğa Etkisi. Dumlupınar Üniversitesi İİBF Dergisi, (10), 16-36.
  24. Sudershan, K., V. R. Muppani, M. Khan and A. Ali (2012). Foreign direct investment and export performance of pharmaceutical firms in India: An empirical approach. International Journal of Economics and Finance, 4(5).
  25. Suri, F. K., and A. Banerji (2016). A study of disaggregated R&D expenditure on Indian pharmaceutical exports. The Journal of Developing Areas, 167-190.
  26. Tosunoğlu, M., Akpınar, A., Erdemir, N. A., & Aslan, T. (2025). Fiyatların Gölgesinde Doğal Kaynaklar: Türkiye'de Enflasyonun Doğal Kaynak Politikalarına Yansımaları. Manisa Celal Bayar Üniversitesi Sosyal Bilimler Dergisi, 23(3), 195-213.
  27. Türkiye İstatistik Kurumu (TÜİK). (2025). Dış Ticaret İstatistikleri (Biruni Dış Ticaret Uygulaması) [Web uygulaması]. TÜİK. Retrieved August 13, 2025, from https://biruni.tuik.gov.tr/disticaretapp/menu.zul
  28. Tyagi, S., D. K. Nauriyal and R. Gulati (2018). Firm level R&D intensity: evidence from Indian pharmaceuticals and pharmaceutical industry. Review of Managerial Science, 12, 167-202.
  29. Uzay, N., M. Demir and E. Yildirim (2012). İhracat performansi açisindan teknolojik yeniliğin önemi: Türkiye imalat sanayi örneği. Doğuş Üniversitesi Dergisi, 13(1), 147-160.
  30. Yıldırım, H. H., M. E. Akkılıç and M. S. Dikici (2019). ARGE Harcamalarının Ekonomik Büyüme ve Dış Ticaret Dengesi Üzerindeki Etkisi: G-20 Ülkeleri Üzerine Bir Uygulama. International Review of Economics and Management, 6(2), 43-58.
  31. Yıldırım, E. and F. Kesikoğlu (2015). ARGE Harcamaları ile İhracat Arasındaki Nedensellik İlişkileri: Türkiye Örneğinde Panel Nedensellik Testi Kanıtları. Marmara Üniversitesi İktisadi ve İdari Bilimler Dergisi, 32(1), 165-180.
  32. Zivot, E. and D. W. K. Andrews (2002). Further evidence on the great crash, the oil price shock, and the unit-root hypothesis. Journal of business & economic statistics, 20(1), 25-44.
  33. World Bank. (2025). World development indicators. World Bank. Retrieved August 13, 2025, from https://databank.worldbank.org/source/world-development-indicators