Journals / EMU Journal of Pharmaceutical Sciences / 2026 / Volume: 9 Issue: 1

The Enduring Legacy of Medicinal and Aromatic Plants from Ancient Civilizations to Modern Era – A Brief Overview

İlkay Erdoğan Orhan(LOKMAN HEKİM ÜNİVERSİTESİ, ECZACILIK FAKÜLTESİ)0000-0002-7379-5436
Pages
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Publication Date
2026-05-21
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The paper concludes that herbal medicine developed as a cumulative global endeavour, supported by exchange routes like the Silk Road, and continues to inform modern pharmacognosy and the ongoing search for novel therapeutics.

📌 3 Key Takeaways

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Objective & Hypothesis:The historical utilization of medicinal and aromatic plants (MAPs) represents a cornerstone in the development of global medical and pharmaceutical sciences.
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Key Findings & Data:Beginning with the Mesopotamians, where empirical healers (asû) and ritual exorcists (āšipu) integrated botanical therapy with spiritual practice—the narrative expands to Ancient Egypt, highlighting herbal pharmacopoeias documented in the Ebers and Edwin Smith Papyri.
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Conclusion & Impact:The paper concludes that herbal medicine developed as a cumulative global endeavour, supported by exchange routes like the Silk Road, and continues to inform modern pharmacognosy and the ongoing search for novel therapeutics.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Medicinal and aromatic plants · traditional medicine · history of pharmacy

Abstract

The historical utilization of medicinal and aromatic plants (MAPs) represents a cornerstone in the development of global medical and pharmaceutical sciences. This paper reviews the ancient wisdom surrounding MAPs, tracing their systematic use from the earliest recorded civilizations to the late pre modern era. Beginning with the Mesopotamians, where empirical healers (asû) and ritual exorcists (āšipu) integrated botanical therapy with spiritual practice—the narrative expands to Ancient Egypt, highlighting herbal pharmacopoeias documented in the Ebers and Edwin Smith Papyri. The theoretically-grounded systems of Traditional Chinese Medicine and Ayurveda are examined. The analysis further encompasses the Hittite, Greco-Roman, and pre-Columbian South American civilizations, underscoring the systematic and often spiritually-embedded nature of their plant-based therapies. A significant focus is placed on the Islamic Golden Age, where pharmacy emerged as an independent, regulated profession, and scholars such as Al-Razi, Ibn Sina, and Ibn al-Baytar advanced botanical science through critical compilation and cross-cultural synthesis. Finally, the Ottoman synthesis of this inherited knowledge is explored, highlighting its integration of diverse traditions and advanced galenical techniques. The paper concludes that herbal medicine developed as a cumulative global endeavour, supported by exchange routes like the Silk Road, and continues to inform modern pharmacognosy and the ongoing search for novel therapeutics.

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Cite This Article

Orhan, İ. E., Deniz, F. S. Ş. (2026). The Enduring Legacy of Medicinal and Aromatic Plants from Ancient Civilizations to Modern Era – A Brief Overview. EMU Journal of Pharmaceutical Sciences, Volume: 9 Issue: 1. https://doi.org/10.54994/emujpharmsci.1843372

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References (39)

  1. Aciduman A, Arda B (2006). Abu'l-Kasim Ez-Zehravi, his work on the treatment of Et-Tasrif and hydrocephalus. Journal of Child Health and Diseases 49: 169-173.
  2. Aciduman A (2002). Role of Ibn-i Sina in science history. An approach by Kuhn. J Ankara Univ Fac Med 55: 115-122.
  3. Akdeniz Sari N (1983). Medical education until the establishment of the medicine in the Ottomans. Studies on Turkish World 22: 152.
  4. Akhlaq S, Ara SA, Ahmad B, Fazil M, Akram U, et al. (2021). Interventions of Unani medicine for maintenance of health with special reference to air quality: An evidence-based review. Rev Environ Health 38: 85-96.
  5. Akhtari M, Mojahedi M, Gorji N, Bijani A, Mozaffarpur SA, et al. (2024). Development and validation of self report Mizaj identification questionnaire based on Persian Medicine for the elders (age over 60). CASP J INTERN MED 15:76-86.
  6. Alam MA, Quamri MA, Sofi G (2021). Historical account of endocrinal disorders in Unani medicine. J Basic Clin Physiol Pharmacol 32: 1013-1019.
  7. Aleem M, Khan MI (2023). Concept of dementia (Nisyān) in Unani system of medicine and scientific validation of an important Unani pharmacopoeial preparation 'Majoon Vaj' for its management: A review. Journal of Complementary and Integrative Medicine 21: 139-153.
  8. Apuzzo ML (2000). The legacy of Galen of Pergamon. Neurosurgery 47: 545.
  9. Asil E (2001). Pharmacy from yesterday to today. Magazine of Continuing Education (MISED) by Turkish Pharmacists Association 1: 4-19.
  10. Azizi MH (2008). Gondishapur School of Medicine: The most important medical center in antiquity. Archives of Iran Medicine 11(1): 116-119.
  11. Baytop T (2000). Dioscorides of Anazarba, Studies on Turkish Pharmacy History, Istanbul.
  12. Goss CM, Chodkowski EG (1985). Whether blood is contained in the arteries of the living animal by Galen of Pergamon: A translation. The Anatomical Record 213: 1-6.
  13. Edriss H, Rosales BN, Nugent C, Conrad C, Nugent K (2017). Islamic medicine in the Middle Ages. American Journal of Medical Sciences 354: 223-229.
  14. Elsawaby MNE (2012). Medicinal and aromatic crops in Egypt: A study in medical geography. Journal of Educational and Social Research 2: 112-124.
  15. Griffin JP. (2004). Venetian treacle and the foundation of medicines regulation. British Journal of Clinical Pharmacology 58: 317-325.
  16. Hizmetli S (1991). History of Islam. Ankara University Faculty of Theology Publications, No. 189, Ankara University Press house, Ankara, 1991.
  17. Huff T (2003). The Rise of Early Modern Science: Islam, China, and the West, Cambridge University Press, Cambridge.
  18. Itrat M. Methods of health promotion and disease prevention in Unani medicine (2020). Journal of Education in Health Promotion 9: 168.
  19. Kahya E (1992). Zehravi. Encyclopedia of Islam by Religious Foundation of Turkey, Vol. 6, Istanbul.
  20. Karaoz Arıhan S (2003). Medicine and herbal treatment in antiquity, Master Thesis, Ankara University, Institute of Social Sciences, Department of Archeology, Ankara.
  21. Kausar F, Yusuf Amin KM, Bashir S, Parvez A, Ahmad P (2021). Concept of 'Ihtiraq' in Unani Medicine - A correlation with oxidative stress, and future prospects. Journal of Ethnopharmacology 265: 113269.
  22. Masic I, Skrbo A, Naser N, Tandir S, Zunic L, et al. (2017). Contribution of Arabic medicine and pharmacy to the development of health care protection in Bosnia and Herzegovina - The first part. Medical Archives 71(5): 364 372.
  23. Mishra SK, Mohammad Khanli H, Akhlaghipour G, Jazi GA, Khosa S (2019). Historical perspective of neurology in Iran. Iran Journal of Neurology 18: 25-32.
  24. Modanlou HD (2011). Historical evidence for the origin of teaching hospital, medical school and the rise of academic medicine. Journal of Perinatology 31(4): 236-239.
  25. Pormann PE (2008). Case notes and clinicians: Galen's "Commentary" on the Hippocratic "Epidemics" in the Arabic tradition. Arabic Sciences and Philosophy 18: 247-284.
  26. Ruben RJ (2017). Otology at the Academy of Gondishapur 200-600 CE. Otology and Neurotology 38(10): 1540 1545.
  27. Sadeghi S, Ghaffari F, Heydarirad G, Alizadeh M (2020). Galen's place in Avicenna's The Canon of Medicine: Respect, confirmation and criticism. Journal of Integrative Medicine 18: 21-25.
  28. Scarborough J (2007). Dioscorides of Anazarbus for moderns - An essay review. Pharmacy in History 49: 76-80.
  29. Singer C, Underwood EA (1962). Short History of Medicine, Oxford University Press, New York and Oxford.
  30. Staub PO, Casu L, Leonti M (2016). Back to the roots: A quantitative survey of herbal drugs in Dioscorides' De Materia Medica (ex Matthioli, 1568). Phytomedicine 23: 1043-1052.
  31. Tanker M, Tanker N (1991). Pharmacognosy, Volume 1, Ankara University Faculty of Pharmacy Publications, No: 60, Ankara University Press house, Ankara.
  32. Tekiner H (2015). One hundred years of the history of pharmacy studies in Turkey. Pharmazie 70: 139–144.
  33. Theophrastus (Translated from ancient Greek language by Sentuna C.) (1998). Characters, Dost Book House Publications, Ankara.
  34. Totelin L (2004). Mithridates' antidote – A pharmacological ghost. Early Science and Medicine 9: 1-19.
  35. Tumer G (1992). Biruni. Encyclopedia of Islam by Religious Foundation of Turkey, Vol. 6, Istanbul.
  36. Unal A (1980). Main lines of Hittite medicine. Belleten 44: 475-480.
  37. Unschuld P (1986). Medicine in China: A History of Pharmaceutics. University of California Press, Berkeley, California.
  38. Unschuld P (1988). Chinese Medicine. Mass Paradigm Publications, Brookline.
  39. Yuan H, Ma Q, Ye L, Piao G (2016). The traditional medicine and modern medicine from natural products. Molecules 21(5): 559.