Journals / Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi / 2020 / Cilt: 25 - Sayı: 1

Gastroenteritis of Salmonella enterica subsp. enterica and Cryptosporidium spp. in a Patient with Common Variable Immunodeficiency: A Case Report

Yaygın Değişken İmmünyetmezlik Tanılı Bir Olguda Salmonella enterica subsp. enterica ve Cryptosporidium spp. Gastroenteriti: Olgu Sunumu

Pages
98–101
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In patients with common variable immunodeficiency, infectious causes of acute and chronic diarrhea should be kept in mind both in diagnosis and choosing of empirical treatment.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Common variable immunodeficiency is the most common primary immunodeficiency syndrome in adults, characterized by recurrent opportunistic infections, particularly bacterial, and hypogammaglobulinemia.
📊
Key Findings & Data:In this report, a 50-year-old male patient with common variable immunodeficiency was presented with complaints of gastrointestinal infection.
💡
Conclusion & Impact:In patients with common variable immunodeficiency, infectious causes of acute and chronic diarrhea should be kept in mind both in diagnosis and choosing of empirical treatment.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Common variable immunodeficiency is the most common primary immunodeficiency syndrome in adults, characterized by recurrent opportunistic infections, particularly bacterial, and hypogammaglobulinemia. In this report, a 50-year-old male patient with common variable immunodeficiency was presented with complaints of gastrointestinal infection. Salmonella enterica subsp. enterica was yielded in the bacteriological examination of the stool sample. Cryptosporidium spp. oocysts were also seen in concurrent parasitological examination. In patients with common variable immunodeficiency, infectious causes of acute and chronic diarrhea should be kept in mind both in diagnosis and choosing of empirical treatment.

Özet

Yaygın değişken immünyetmezlik (YDİ), başta bakteriyel olmak üzere tekrarlayan fırsatçı infeksiyonlar ve hipogamaglobulinemi ile karakterize, erişkinde en sık görülen primer immünyetmezlik sendromudur. Bu yazıda, YDİ tanılı gastrointestinal sistem infeksiyonu yakınmalarıyla başvuran 50 yaşında erkek bir olgu sunulmaktadır. Dışkı örneğinin bakteriyolojik incelemesinde Salmonella enterica subsp. enterica üremesi olmuştur. Eş zamanlı parazitolojik incelemesinde de Cryptosporidium spp. ookistleri görülmüştür. YDİ tanılı olgularda infeksiyöz nedenli akut ve kronik ishal etkenleri hem tanı hem de ampirik tedavi seçiminde akılda tutulmalıdır.

🔖

Cite This Article

AKYOL, D., ŞİMŞİR, I. Y., ISMAYILOV, R., ARDENİZ, F. Ö., IŞIKGÖZ, M. T., PULLUKÇU, H. (2020). Gastroenteritis of Salmonella enterica subsp. enterica and Cryptosporidium spp. in a Patient with Common Variable Immunodeficiency: A Case Report. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, Cilt: 25 - Sayı: 1, 98–101. https://ajindex.com/articles/158009

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Conley ME, Notarangelo LD, Etzioni A. Diagnostic criteria for primary immunodeficiencies. Representing PAGID (Pan-American Group for Immunodeficiency) and ESID (European Society for Immunodeficiencies). Clin Immunol 1999;93:190-7
  2. Hermaszewski RA, Webster AD. Primary hypogammaglobulinaemia: a survey of clinical manifestations and complications. QJ Med 1993;86:31-42
  3. Cunningham-Rundles C, Bodian C. Common variable immunodeficiency: clinical and immunological features of 248 patients. Clin Immunol 1999;92:34-48
  4. Quinti I, Soresina A, Spadaro G, Martino S, Donnanno S, Agostini C, et al.; Italian Primary Immunodeficiency Network. Long-term follow-up and outcome of a large cohort of patients with common variable immunodeficiency. J Clin Immunol 2007;27:308-16
  5. Woodward JM, Gkrania-Klotsas E, Cordero-Ng AY, Aravinthan A, Bandoh BN, Liu H, et al. The role of chronic norovirus infection in the enteropathy associated with common variable immunodeficiency. Am J Gastroenterol 2015;110:320-7
  6. Hammarstrom L, Vorechovsky I, Webster D. Selective IgA deficiency (SIgAD) and common variable immunodeficiency (CVID). Clin Exp Immunol 2000;120:225-31
  7. Cunningham-Rundles C. How I treat common variable immune deficiency. Blood 2010;116(1):7-15
  8. Pickering LK, DuPont HL, Olarte J, Conklin R, Ericsson C. Fecal leukocytes in enteric infections. Am J Clin Pathol 1977;68(5):562-5
  9. Diskin A, Gutierrez-Alvarez L. Emergent treatment of gastroenteritis workup. https://emedicine.medscape.com/article/775277-workup. Accessed September 21, 2019
  10. Uysal S, Tunalı V, Akdur Öztürk E, Ardeniz Ö, Işıkgöz Taşbakan M, Pullukçu H, et al. Incidence of parasitic diarrhea in patients with common variable immune deficiency. Turkiye Parazitol Derg 2016;40(2):67-71
  11. Altenburg J, Graaff CS, Stienstra Y, Sloos JH, van Haren EH, Koppers RJ, et al. Effect of azithromycin maintenance treatment on infectious exacerbations among patients with non-cystic fibrosis bronchiectasis: the BAT randomized controlled trial. JAMA 2013;309:1251-9
  12. Leder K, et al. Epidemiology, clinical manifestations, diagnosis, treatment and prevention of Cryptosporidiosis. http:// www.uptodate.com/home. Accessed September 21, 2019
  13. Crump JA, Medalla FM, Joyce KW, Krueger AL, Hoekstra RM, Whichard JM, Barzilay EJ. Antimicrobial resistance among invasive nontyphoidal Salmonella enterica isolates in the United States: National Antimicrobial Resistance Monitoring System, 1996 to 2007. Antimicrob Agents