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Journals / Türk Kadın Sağlığı ve Neonatoloji Dergisi / 2026 / Volume: 3 Issue: 3

The Relationship Between Sperm Parameters and Pregnancy Outcomes in Patients Undergoing Intra Uterine Insemination

İntrauterin İnseminasyon Uygulanan Hastalarda Sperm Parametrelerinin Gebelik Sonuçları ile İlişkisi

Cuma Taşın(Mersin üniversite)0000-0002-9315-4791
Gülnur Özakşit(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA DR. ZEKAİ TAHİR BURAK KADIN SAĞLIĞI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0001-9117-9728
Pages
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Publication Date
2021-09-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It was found that smoking in men decreased morphology, while varicocele decreased both total progressive motile sperm count and morphology.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Intrauterine insemination is a widely used method in infertile patients.
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Key Findings & Data:Material and Method: In this study; 300 cycles of 170 infertile patients who underwent intrauterine insemination after ovulation induction with recombinant FSH in the infertility outpatient clinic of the Dr.
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Conclusion & Impact:It was found that smoking in men decreased morphology, while varicocele decreased both total progressive motile sperm count and morphology.
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:Intrauterine insemination · sperm parameters · total progressive motile sperm count

Abstract

Aim: Intrauterine insemination is a widely used method in infertile patients. Sperm parameters that affect pregnancy success in these patients are still a problematic issue. This study aims to determine the effect of sperm parameters on intrauterine insemination results. Material and Method: In this study; 300 cycles of 170 infertile patients who underwent intrauterine insemination after ovulation induction with recombinant FSH in the infertility outpatient clinic of the Dr. Zekai Tahir Burak Women's Health Training and Research Hospital between January 2009 and January 2011 were examined. Age, basal FSH, total FSH dose used, number of treatment cycles, smoking, varicocele, semen parameters and treatment results were compared. Patients were divided into groups as Total progressive motile sperm count ≤10 million and >10 million, morphology ≤4% and morphology >4% in semen parameters. Pregnancy results of total progressive motile sperm count and morphology groups were analyzed. In male patients, the effects of smoking and varicocele on total progressive motile sperm count and morphology from sperm parameters were evaluated. Results: No statistically significant difference was found between the total progressive motile sperm count ≤10 million and total progressive motile sperm count >10 million groups and between the morphology≤4% and morphology>4% groups in terms of clinical pregnancy rates. It was found that smoking in men decreased morphology, while varicocele decreased both total progressive motile sperm count and morphology. Conclusion: Pregnancy rates in intrauterine insemination cycles show no correlation with either morphology alone or total progressive motile sperm count alone. It was found that smoking in infertile men decreased pregnancy rates by particularly disrupting the morphology. It was concluded that varicocele reduces both morphology and total progressive motile sperm count in male patients, but this does not affect pregnancy outcomes.

Özet

Amaç: İnfertil hastalarda intrauterin inseminasyon yaygın kullanılan bir yöntemdir. Bu hastalardaki gebelik başarısını etkileyen sperm parametreleri ise hala tartışmalı bir konudur. Bu çalışmamız sperm parametrelerinin intrauterin inseminasyon sonuçlarına etkisini tayin etmeyi amaçlamaktadır. Gereç ve Yöntem: Çalışmamız Ocak 2009-Ocak 2011 tarihleri arasında Dr. Zekai Tahir Burak Kadın Sağlığı Eğitim ve Araştırma Hastanesi infertilite polikliniğinde rekombinant FSH ile ovulasyon indüksiyonu oluşturulup intrauterin inseminasyon uygulanan 170 infertil hastanın 300 siklusunun incelendiği bir çalışmadır. Yaş, bazal FSH, toplam kullanılan FSH dozu, tedavi siklus sayısı, sigara kullanımı, varikosel ve semen parametreleri ile tedavi sonuçları karşılaştırıldı. Hastaların semen parametrelerinde total progresif motil sperm sayısı ≤10 milyon ve >10 milyon , morfoloji ise ≤ % 4 ve >% 4 olarak gruplara ayrıldı. Total progresif motil sperm sayısı ve morfoloji gruplarının gebelik sonuçlarına bakıldı. Erkek hastalarda sigara kullanımı ve varikoselin total progresif motil sperm sayısı ve morfolojiye olan etkilerine bakıldı. Bulgular: Total progresif motil sperm sayısı <10 milyon ve ≥10 milyon grupları arasında ve morfoloji ≤% 4 ve >% 4 grupları arasında klinik gebelik oranları açısından istatiksel olarak anlamlı fark saptanmadı. Erkelerde sigara kullanımının normal morfolojideki sperm sayısının azalttığı, varikoselin ise hem total progresif motil sperm sayısını hem de normal morfolojideki sperm sayısının azalttığı bulundu. Sonuç: İntrauterin inseminasyon sikluslarındaki gebelik oranları ne tek başına morfoloji ne de tek başına total progresif motil sperm sayısı ile korelasyon göstermektedir. İnfertil erkeklerde sigara kullanımının özellikle morfolojiyi bozarak gebelik oranlarını azalttığı saptandı. Varikoselin hem morfolojiyi hem de total progresif motil sperm sayısını azalttığı fakat bunun gebelik sonuçlarını etkilemediği sonucuna ulaşıldı.

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Cite This Article

Taşın, C., Özakşit, G. (2021). The Relationship Between Sperm Parameters and Pregnancy Outcomes in Patients Undergoing Intra Uterine Insemination. Türk Kadın Sağlığı ve Neonatoloji Dergisi, Volume: 3 Issue: 3. https://doi.org/10.46969/ezh.962608

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