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Journals / Turkish Journal of Internal Medicine / 2026 / Volume: 4 Special Issue

Indomethacin induced toxic hepatitis: a case report

Orkun Sakar(BURSA ULUDAĞ ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, İÇ HASTALIKLARI ANABİLİM DALI)0000-0002-1624-4339
Tufan Teker(BURSA ULUDAĞ ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, İÇ HASTALIKLARI ANABİLİM DALI, GASTROENTEROLOJİ BİLİM DALI)0000-0002-8211-2561
Selim Giray Nak(BURSA ULUDAĞ ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, İÇ HASTALIKLARI ANABİLİM DALI, GASTROENTEROLOJİ BİLİM DALI)0000-0001-7295-4063
Nesrin Uğraş(BURSA ULUDAĞ ÜNİVERSİTESİ, TIP FAKÜLTESİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ, TIBBİ PATOLOJİ ANABİLİM DALI)0000-0003-0127-548X
Pages
—
Publication Date
2022-04-01
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Here, we present a case of indomethacin-induced toxic hepatitis that improved with methylprednisolone treatment.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Nonsteroidal anti-inflammatory drugs deare widely used worldwide for analgesic, antipyretic and anti-inflammatory purposes.
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Key Findings & Data:Indomethacin is a potent nonsteroidal anti-inflammatory drug and can cause severe liver damage.
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Conclusion & Impact:Here, we present a case of indomethacin-induced toxic hepatitis that improved with methylprednisolone treatment.
🔬Design:Case Report
📍Scope:Comprehensive Sample
⚙️Variables:Drug induced liver injury · toxic hepatitis · Indomethacin

Abstract

Nonsteroidal anti-inflammatory drugs deare widely used worldwide for analgesic, antipyretic and anti-inflammatory purposes. Indomethacin is a potent nonsteroidal anti-inflammatory drug and can cause severe liver damage. Few cases of idiosyncratic toxic hepatitis have been reported. Here, we present a case of indomethacin-induced toxic hepatitis that improved with methylprednisolone treatment.

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Cite This Article

Sakar, O., Teker, T., Nak, S. G., Uğraş, N. (2022). Indomethacin induced toxic hepatitis: a case report. Turkish Journal of Internal Medicine, Volume: 4 Special Issue. https://doi.org/10.46310/tjim.1072846

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