Journals / Turkish Journal of Internal Medicine / 2026 / Volume: 4 Issue: 2

Marginal zone lymphoma presenting in a patient with autoimmune hemolytic anemia: a case report

Büşra Güner(ULUDAĞ ÜNİVERSİTESİ, SAĞLIK BİLİMLERİ ENSTİTÜSÜ, İÇ HASTALIKLARI (DR))0000-0001-6320-9512
Bedrettin Orhan(BURSA ULUDAĞ ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, İÇ HASTALIKLARI ANABİLİM DALI, HEMATOLOJİ BİLİM DALI)0000-0003-3970-2344
Tuba Ersal(BURSA ULUDAĞ ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, İÇ HASTALIKLARI ANABİLİM DALI, HEMATOLOJİ BİLİM DALI)0000-0001-5419-3221
Vildan Ozkocaman(BURSA ULUDAĞ ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, İÇ HASTALIKLARI ANABİLİM DALI, HEMATOLOJİ BİLİM DALI)0000-0003-0014-7398
Rıdvan Ali(BURSA ULUDAĞ ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, İÇ HASTALIKLARI ANABİLİM DALI, HEMATOLOJİ BİLİM DALI)0000-0001-6486-3399
Fahir Özkalemkaş(BURSA ULUDAĞ ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, İÇ HASTALIKLARI ANABİLİM DALI, HEMATOLOJİ BİLİM DALI)
Pages
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Publication Date
2022-04-29
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We found it appropriate to present our MZL case because of its response to steroid treatment and its rare presentation with AIHA.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:While autoimmune hemolytic anemia (AIHA) is expected in non-Hodgkin’s lymphomas, it is less common in marginal zone lymphoma.
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Key Findings & Data:Sixty-year-old male patient was followed up with hemolytic anemia in our clinic and while the etiology was investigated, scattered nodes in the mediastinum and abdomen compatible with lymphoproliferative disease were observed on CT, and positive detection of CD5, CD19, CD20, CD22, CD45, HLA-DR, FMC-7 on flow cytometry sent from peripheral blood and a diagnosis of low grade B cell lymphoma (MZL) was made with the result of bone marrow pathology.
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Conclusion & Impact:We found it appropriate to present our MZL case because of its response to steroid treatment and its rare presentation with AIHA.
🔬Design:Case Report
📍Scope:Comprehensive Sample
⚙️Variables:AUTOIMMUNE HEMOLITHIC ANEMIA · MARGINAL ZONE LYMPHOMA · LYMPHOMA

Abstract

While autoimmune hemolytic anemia (AIHA) is expected in non-Hodgkin’s lymphomas, it is less common in marginal zone lymphoma. Sixty-year-old male patient was followed up with hemolytic anemia in our clinic and while the etiology was investigated, scattered nodes in the mediastinum and abdomen compatible with lymphoproliferative disease were observed on CT, and positive detection of CD5, CD19, CD20, CD22, CD45, HLA-DR, FMC-7 on flow cytometry sent from peripheral blood and a diagnosis of low grade B cell lymphoma (MZL) was made with the result of bone marrow pathology. We found it appropriate to present our MZL case because of its response to steroid treatment and its rare presentation with AIHA.

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Cite This Article

Güner, B., Orhan, B., Ersal, T., Ozkocaman, V., Ali, R., Özkalemkaş, F. (2022). Marginal zone lymphoma presenting in a patient with autoimmune hemolytic anemia: a case report. Turkish Journal of Internal Medicine, Volume: 4 Issue: 2. https://doi.org/10.46310/tjim.904114

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