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Journals / Turkish Journal of Internal Medicine / 2026 / Volume: 6 Issue: 1

Combined Use of Different Vaccine Models for Covid-19 And The Side-Effect Profile: A Single-Center Experience

Ali Avcı(Karaman Training and Research Hospita)0000-0002-7019-1012
Muhammet Özer(Karaman Training and Research Hospita)0000-0002-4670-2476
Mehmet Serkan Yurdakul(Karaman Training and Research Hospita)0000-0003-1954-8845
Hakan Ozer(Konya City Hospital)0000-0001-9174-0351
İsmail Baloğlu(NECMETTİN ERBAKAN ÜNİVERSİTESİ, MERAM TIP FAKÜLTESİ, MERAM TIP PR.)0000-0002-8751-5490
Pages
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Publication Date
2024-01-29
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion Different vaccine methods did not change the side effect profile, so different vaccine combinations could be used together if necessary.

📌 3 Key Takeaways

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Objective & Hypothesis:Background Currently, the most effective method to combat the COVID-19 pandemic is vaccination.
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Key Findings & Data:Methods This cross-sectional study evaluated 437 people (265 females, 172 males; mean age, 42.04±14.49 years) who applied to the emergency department due to side effects among 26,974 vaccinated people (13,460 females, 13,514 males).
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Conclusion & Impact:Conclusion Different vaccine methods did not change the side effect profile, so different vaccine combinations could be used together if necessary.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Covid-19 · vaccine · side-effect

Abstract

Background Currently, the most effective method to combat the COVID-19 pandemic is vaccination. This study investigated whether the combined use of vaccines obtained by different methods affected the side-effect profile. Methods This cross-sectional study evaluated 437 people (265 females, 172 males; mean age, 42.04±14.49 years) who applied to the emergency department due to side effects among 26,974 vaccinated people (13,460 females, 13,514 males). The complaints and outcomes of the patients who applied to the emergency department were recorded. Results While the rate of admission to the emergency department due to post-vaccination side effects was 1.6% among all vaccinated participants, this rate was 3% in the mixed vaccination group. It was observed that hospitalization was required in only two patients due to side effects. When vaccination methods were compared, the frequency of admission to the emergency department due to side effects was higher in the patients in the group in which the mRNA vaccine was mixed with the booster shot. However, it was not statistically significant (p=0.113). Conclusion Different vaccine methods did not change the side effect profile, so different vaccine combinations could be used together if necessary.

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Cite This Article

Avcı, A., Özer, M., Yurdakul, M. S., Ozer, H., Baloğlu, İ. (2024). Combined Use of Different Vaccine Models for Covid-19 And The Side-Effect Profile: A Single-Center Experience. Turkish Journal of Internal Medicine, Volume: 6 Issue: 1. https://doi.org/10.46310/tjim.1343477

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