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Journals / Turkish Journal of Analytical Chemistry / 2024 / Cilt: 6 Sayı: 2

Parentucellia viscosa (growing in Türkiye): Essential oil, phenolic composition, antimicrobial and lipase inhibition

Büşra Korkmaz(Karadeniz technical university)0000-0002-3747-8855
Gözde Bozdal(karadeniz technical university)0000-0003-1248-7912
Büşra Şahin(KARADENİZ TEKNİK ÜNİVERSİTESİ)0000-0002-2727-9801
Sıla Özlem Sener(University of Health Sciences)0000-0001-7679-7165
Elif Öztürk(KARADENİZ TEKNİK ÜNİVERSİTESİ, SAĞLIK BİLİMLERİ ENSTİTÜSÜ)0000-0002-0809-6145
Seda Fandakli(ARTVIN CORUH UNIVERSITY, HEALTH SERVICES VOCATIONAL SCHOOL, DEPARTMENT OF MEDICAL SERVICES AND TECHNIQUES)0000-0002-8199-3336
Şengül Alpay Karaoğlu(RECEP TAYYİP ERDOĞAN ÜNİVERSİTESİ, FEN BİLİMLERİ ENSTİTÜSÜ, BİYOLOJİ (DR))0000-0003-1047-8350
Nurettin Yaylı(KARADENIZ TECHNICAL UNIVERSITY, FACULTY OF PHARMACY, PHARMACY PR.)0000-0003-4174-3014
Pages
91–96
Publication Date
2024-12-20
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The highest lipase enzyme inhibition activity was detected in the n-hexane extract with 44.22±1.1628 µg/mL IC50 value.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The essential oil (EO) and phenolic constituents of Parentucellia viscosa L. were analyzed by GC-FID-MS and HPLC, respectively.
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Key Findings & Data:A total of 20 volatile compounds were identified accounting for 99.97% in hydrodistillation.
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Conclusion & Impact:The highest lipase enzyme inhibition activity was detected in the n-hexane extract with 44.22±1.1628 µg/mL IC50 value.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Parentucellia viscosa · essential oil · phenolic

Abstract

The essential oil (EO) and phenolic constituents of Parentucellia viscosa L. were analyzed by GC-FID-MS and HPLC, respectively. A total of 20 volatile compounds were identified accounting for 99.97% in hydrodistillation. Monoterpenes (50.57%, 5 compounds) were the primary chemical class in the essential oil of P. viscosa. Limonene (44.02%) and 1-octen-3-ol (25.23%) were the major components in the essential oil of P. viscosa. The phenolic constituent analysis for the methanol extract of P. viscosa gave benzoic acid (0.97 mg/g) as the major compound. The antimicrobial activities of the EO and crude solvent (n-hexane, acetonitrile, methanol, and water) extracts of P. viscosa were screened in vitro against ten microorganisms. n-Hexane and the acetonitrile extracts of P. viscosa resulted in the best activity against Mycobacterium smegmatis with IC50 values of 19.2 µg/mL and 53.8 µg/mL, respectively. The highest lipase enzyme inhibition activity was detected in the n-hexane extract with 44.22±1.1628 µg/mL IC50 value.

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Cite This Article

Korkmaz, B., Bozdal, G., Şahin, B., Sener, S. Ö., Öztürk, E., Fandakli, S., Karaoğlu, Ş. A., Yaylı, N. (2024). Parentucellia viscosa (growing in Türkiye): Essential oil, phenolic composition, antimicrobial and lipase inhibition. Turkish Journal of Analytical Chemistry, Cilt: 6 Sayı: 2, 91–96. https://doi.org/10.51435/turkjac.1513093

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