We present a 22-year-old male patient with familial hypercholesterolemia and concomitant supravalvular aortic stenosis and coronary artery disease treated with hybrid coronary revascularization approach.
📌 3 Key Takeaways
🎯
Objective & Hypothesis:Familial hypercholesterolemia (FH) is an autosomal dominant inherited metabolic disorder characterized with high levels of low-density lipoprotein (LDL) plasma cholesterol.
📊
Key Findings & Data:Increased plasma LDL-cholesterol levels cause cutaneous and tendinous xanthomas, supravalvular aortic stenosis and coronary ostial stenosis in younger ages.
💡
Conclusion & Impact:We present a 22-year-old male patient with familial hypercholesterolemia and concomitant supravalvular aortic stenosis and coronary artery disease treated with hybrid coronary revascularization approach.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Özet
Familial hypercholesterolemia (FH) is an autosomal dominant inherited metabolic disorder characterized with high levels of low-density lipoprotein (LDL) plasma cholesterol. Increased plasma LDL-cholesterol levels cause cutaneous and tendinous xanthomas, supravalvular aortic stenosis and coronary ostial stenosis in younger ages. Complications can be fatal if it is not diagnosed and treated in preliminary stages. We present a 22-year-old male patient with familial hypercholesterolemia and concomitant supravalvular aortic stenosis and coronary artery disease treated with hybrid coronary revascularization approach.
🔖
Cite This Article
SELÇUK, İ., UĞUR, M., ALP, İ., TEMİZKAN, V., SELÇUK, A., YEDEKÇİ, E., YILMAZ, A. T. (2018). Hybrid Treatment of Supravalvular Aortic Stenosis and Coronary Ostial Stenosis in Familial Hypercholesterolemia. E Journal of Cardiovascular Medicine, Cilt: 6 - Sayı: 2, 68–71. https://ajindex.com/articles/154334
Kawasuji M, Sakakibara N, Takemura H, Matsumoto Y, Mabuchi H, Watanabe Y. Coronary artery bypass grafting in familial hypercholesterolemia. J Thorac Cardiovasc Surg. 1995;109:364-369
Qaiser S, Sheikh S, Malik MS. Homozygous Familial Hypercholestrolaemia presents with supravalvular aortic stenosis, J Pak Med Assoc. 2012;62:612-614
Srimannarayana I, Varma RS, Satheesh S, Anilkumar R, Balachander J. Supravalvular Aortic Stenosis and Coronary Ostial Stenosis in Homozygous Familial Hypercholesterolemia. Indian Heart J. 2004;56:152–154
Rallidis L, Naoumova RP, Thompson GR, Nihoyannopoulos P. Extent and severity of atherosclerotic involvement of the aortic valve and root in familial hypercholesterolaemia. Heart. 1998;80:583–590
Beppu S, Minura Y, Sakakibara H, Nagata S, Park YD, Nambu S, Yamamoto A. Supravalvular aortic stenosis and coronary ostial stenosis in familial hypercholesterolemia: two-dimensional echocardiographic assessment. Circulation. 1983;67:878-884
Nemati MH, Astaneh B, Joubeh A. Triple coronary artery bypass graft in a 10-year-old child with familial hypercholesterolemia. Gen Thorac Cardiovasc Surg 2009 57:94–97
Malyshev M, Gladyshev I, Safuanov A, Siniukov D, Borovikov D, Rostovykh N. Surgical angioplasty of the left main coronary artery and/or proximal segment of the right coronary artery by pulmonary autograft patch. Eur J Cardiothorac Surg. 2004;25:21–25
Verhaegh AJ, Accord RE, van Garsse L, Maessen JG. Hybrid coronary revascularization as a safe, feasible, and viable alternative to conventional coronary artery bypass grafting: What is the current evidence? Minim Invasive Surg. 2013;142616.