Journals / Selçuk Sağlık Dergisi / 2026 / Volume: 6 Issue: 2

Pemphigus foliaceus with infection

ENFEKSİYONLA SEYREDEN PEMFIGUS FOLIACEUS

Nisa Akdemir(SELÇUK ÜNİVERSİTESİ, TIP FAKÜLTESİ)0009-0005-2102-9229
Mariye Başer(SELCUK UNIVERSITY, SCHOOL OF MEDICINE, MEDICINE PR.)0009-0005-7613-2741
Ayşe Betül Kaynarca(SELCUK UNIVERSITY, SCHOOL OF MEDICINE, MEDICINE PR.)0009-0002-1959-0410
Cahit Yavuz(SELÇUK ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0003-4675-8127
Pages
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Publication Date
2025-06-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

A multidisciplinary approach ensured accurate and effective treatment.

📌 3 Key Takeaways

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Objective & Hypothesis:Pemphigus foliaceus is an autoimmune disease characterized by the disruption of keratinocyte adhesion due to the formation of autoantibodies against desmoglein-1 glycoproteins.
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Key Findings & Data:A 59-year-old female patient was admitted to the hospital with complaints of fluid-filled blisters and skin lesions.
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Conclusion & Impact:A multidisciplinary approach ensured accurate and effective treatment.
🔬Design:Case Report
📍Scope:Comprehensive Sample
⚙️Variables:Bullous diseases · Autoimmunity · Pemphigus foliaceus

Abstract

Pemphigus foliaceus is an autoimmune disease characterized by the disruption of keratinocyte adhesion due to the formation of autoantibodies against desmoglein-1 glycoproteins. In this study, a case report is presented of a patient diagnosed with pemphigus foliaceus confirmed by biopsy. A 59-year-old female patient was admitted to the hospital with complaints of fluid-filled blisters and skin lesions. She was hospitalized, and a biopsy was taken, which confirmed the diagnosis of pemphigus foliaceus. Treatment with a prednisolone-based medication was initiated, and the process was managed with immunosuppressive drugs. Pseudomonas growth was observed during the course of treatment. After a 4-month hospitalization period, the patient was discharged. A multidisciplinary approach ensured accurate and effective treatment.

Özet

Pemfigus foliaceus; desmoglein-1 glikoproteinlerine karşı otoantikor oluşması sonucu keratinosit hücrelerinin bağlantılarının kopmasıyla meydana gelen otoimmün bir hastalıktır. Bu çalışmada, biyopsi yardımıyla doğrulanmış pemfigus foliaceus tanısı alan bir hastanın olgu sunumu yapıldı. 59 yaşında kadın hasta içi su dolu kabarcık ve yara şikayetiyle hastaneye başvurdu ve hastanın yatışı gerçekleştirildi. Hastadan biyopsi alındı ve pemfigus foliaceus tanısı konuldu. Hastaya prednizolon etken maddeli ilaç tedavisi başlandı, süreç immünosupresif ilaçlarla baskılandı. Hastada Pseudomonas üremesi gözlemlendi. 4 aylık yatış sürecinin ardından hasta taburcu edildi. Multidisipliner yaklaşım, doğru ve etkili tedaviyi sağladı.

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Cite This Article

Akdemir, N., Başer, M., Kaynarca, A. B., Yavuz, C. (2025). Pemphigus foliaceus with infection. Selçuk Sağlık Dergisi, Volume: 6 Issue: 2. https://doi.org/10.70813/ssd.1697775

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References (6)

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