Journals / New Trends in Medicine Sciences / 2026 / Volume: 7 Issue: 2

Pancreatic Acinar Cell Carcinoma with Gastric Metastasis in a Geriatric Patient

Fatih Korkmaz(ATATURK UNIVERSITY, SCHOOL OF MEDICINE)0000-0002-8897-8155
Özlem Polat(ATATURK UNIVERSITY, SCHOOL OF MEDICINE)0000-0003-3238-7652
Sevilay Özmen(ATATURK UNIVERSITY, SCHOOL OF MEDICINE)0000-0002-1973-6101
Adem Maman(ATATURK UNIVERSITY, SCHOOL OF MEDICINE)0000-0002-7742-1028
Pınar Tosun Taşar(ATATURK UNIVERSITY, SCHOOL OF MEDICINE)0000-0002-2617-4610
Pages
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Publication Date
2026-06-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Since gastric metastases are rare and endoscopic diagnosis is difficult, it is very valuable for the lesion biopsy to be evaluated by an experienced pathologist for the correct diagnosis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Pancreatic cancer with gastric metastasis is a rare case and we will present this case.
📊
Key Findings & Data:We will present the imaging and pathology findings of a 71-year-old male patient who was followed in the geriatric clinic to investigate the primary malignancy and was diagnosed with pancreatic acinar cell carcinoma with gastric metastasis.
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Conclusion & Impact:Since gastric metastases are rare and endoscopic diagnosis is difficult, it is very valuable for the lesion biopsy to be evaluated by an experienced pathologist for the correct diagnosis.
🔬Design:Case Report
📍Scope:Comprehensive Sample
⚙️Variables:Pancreatic acinar cell carcinoma · gastric metastasis · geriatric patient

Abstract

Pancreatic cancer with gastric metastasis is a rare case and we will present this case. We will present the imaging and pathology findings of a 71-year-old male patient who was followed in the geriatric clinic to investigate the primary malignancy and was diagnosed with pancreatic acinar cell carcinoma with gastric metastasis. Since gastric metastases are rare and endoscopic diagnosis is difficult, it is very valuable for the lesion biopsy to be evaluated by an experienced pathologist for the correct diagnosis.

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Cite This Article

Korkmaz, F., Polat, Ö., Özmen, S., Maman, A., Taşar, P. T. (2026). Pancreatic Acinar Cell Carcinoma with Gastric Metastasis in a Geriatric Patient. New Trends in Medicine Sciences, Volume: 7 Issue: 2. https://doi.org/10.56766/ntms.1693842

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References (35)

  1. Menuck LS, Amberg JR. Metastatic disease involving the stomach. Am J Dig Dis. 1975;20(10):903-13.
  2. Davis GH, Zollinger RW. Metastatic melanoma of the stomach. Am J Surg. 1960;99(1):94-96.
  3. Higgins PM. Pyloric obstructions due to a metastatic deposit from carcinoma of the bronchus. Can J Surg. 1962;5:438-41.
  4. Green LK. Hematogenous metastases to the stomach. A review of 67 cases. Cancer. 1990;65(7):1596-600.
  5. Kern S, Hruban R, Hollingsworth MA, et al. A white paper: the product of a pancreas cancer think tank. Cancer Res. 2001;61(12):4923-32.
  6. Sperti C, Pasquali C, Piccoli A, Pedrazzoli S. Recurrence after resection for ductal adenocarcinoma of the pancreas. World J Surg. 1997;21(2):195-200.
  7. Griffin JF, Smalley SR, Jewell W, et al. Patterns of failure after curative resection of pancreatic carcinoma. Cancer. 1990;66(1):56-61.
  8. Cannistrà M, Ruggiero M, Zullo A, Serafini S, Grande R, Nardo B. Metastases of pancreatic adenocarcinoma: A systematic review of literature and a new functional concept. Int J Surg. 2015;21 Suppl 1:S15-21.
  9. Blastik M, Plavecz E, Zalatnai A. Pancreatic carcinomas in a 60-year, institute-based autopsy material with special emphasis of metastatic pattern. Pancreas. 2011;40(3):478-80.
  10. Oda, Kondo H, Yamao T, et al. Metastatic tumors to the stomach: analysis of 54 patients diagnosed at endoscopy and 347 autopsy cases. Endoscopy. 2001;33(6):507-10.
  11. Klimstra DS. Nonductal neoplasms of the pancreas. Mod Pathol. 2007;20:S94-S112.
  12. Béchade D, Desjardin M, Salmon E, et al. Pancreatic Acinar Cell Carcinoma. Case Rep Gastroenterol. 2016;10(1):179-85.
  13. Fontenot J, Spieler B, Hudson C, Boulmay B. Pancreatic acinar cell carcinoma-literature review and case report of a 56-year-old man presenting with abdominal pain. Radiol Case Reports. 2020;15(1):39-43.
  14. Raman SP, Hruban RH, Cameron JL, Wolfgang CL, Kawamoto S, Fishman EK. Acinar cell carcinoma of the pancreas: computed tomography features-a study of 15 patients. Abdom Imaging. 2013;38(1):137-43.
  15. Chiou Y-Y, Chiang J-H, Hwang J-I, Yen C-H, Tsay S-H, Chang C-Y. Acinar Cell Carcinoma of the Pancreas. J Comput Assist Tomogr. 2004;28(2):180-86.
  16. Thompson ED, Wood LD. Pancreatic Neoplasms With Acinar Differentiation: A Review of Pathologic and Molecular Features. Arch Pathol Lab Med. 2020;144(7):808-15.
  17. Holen KD, Klimstra DS, Hummer A, et al. Clinical Characteristics and Outcomes From an Institutional Series of Acinar Cell Carcinoma of the Pancreas and Related Tumors. J Clin Oncol. 2002;20(24):4673-78.
  18. Sridharan V, Mino-Kenudson M, Cleary JM, et al. Pancreatic acinar cell carcinoma: A multi-center series on clinical characteristics and treatment outcomes. Pancreatology. 2021;21(6):1119-26.
  19. Klimstra DS, Heffess CS, Oertel JE, Rosai J. Acinar Cell Carcinoma of the Pancreas. Am J Surg Pathol. 1992;16(9):815-37.
  20. Burns WA, Matthews MJ, Hamosh M, Vander Weide G, Blum R, Johnson FB. Lipase-secreting acinar cell carcinoma of the pancreas with polyarthropathy.A light and electron microscopic, histochemical, and biochemical study. Cancer. 1974;33(4):1002-1009.
  21. Seth AK, Argani P, Campbell KA, et al. Acinar Cell Carcinoma of the Pancreas: An Institutional Series of Resected Patients and Review of the Current Literature. J Gastrointest Surg. 2008;12(6):1061-67.
  22. Taskin OC, Adsay V. Lipase hypersecretion syndrome: A distinct form of paraneoplastic syndrome specific to pancreatic acinar carcinomas. Semin Diagn Pathol. 2019;36(4):240-25.
  23. Sofela J, Hunt WTN, Chaytor R, et al. A rare case of lipase hypersecretion syndrome. Clin Exp Dermatol. 2022;47(3):635-38.
  24. Nizam W, Shah AA, Rajack F, Ramdath A, Naab T, Williams M. Lipase hypersecretion syndrome: A rare cutaneous manifestation of advanced pancreatic acinar cell carcinoma. Clin case reports. 2020;8(5):905-10.
  25. Blair AB, Radomski SN, Chou J, et al. Survival Outcomes and Genetic Characteristics of Resected Pancreatic Acinar Cell Carcinoma. Ann Surg Oncol.2025;32:1869-78.
  26. Sakakida T, Ishikawa T, Doi T, Morita R. Genomic landscape and clinical features of rare subtypes of pancreatic cancer: analysis with the national database of Japan. J Gastroenterol. 2023;58(6):575-85.
  27. Petrova E, Wellner J, Nording AK, et al. Survival Outcome and Prognostic Factors for Pancreatic Acinar Cell Carcinoma: Retrospective Analysis from the German Cancer Registry Group. Cancers (Basel). 2021;13(23):612.
  28. Feczko PJ, Collins DD, Mezwa DG. Metastatic Disease Involving the Gastrointestinal Tract. Radiol Clin North Am. 1993;31(6):1359-73.
  29. Schmidt CM, Matos JM, Bentrem DJ, Talamonti MS, Lillemoe KD, Bilimoria KY. Acinar Cell Carcinoma of the Pancreas in the United States: Prognostic Factors and Comparison to Ductal Adenocarcinoma. J Gastrointest Surg. 2008;12(12):2078-86.
  30. Wisnoski NC, Townsend CM, Nealon WH, Freeman JL, Riall TS. 672 patients with acinar cell carcinoma of the pancreas: a population-based comparison to pancreatic adenocarcinoma. Surgery. 2008;144(2):141-48.
  31. Kitagami H, Kondo S, Hirano S, Kawakami H, Egawa S, Tanaka M. Acinar Cell Carcinoma of the Pancreas. Pancreas. 2007;35(1):42-46.
  32. Kryklyva V, Haj Mohammad N, Morsink FHM, et al. Pancreatic acinar cell carcinoma is associated with BRCA2 germline mutations: a case report and literature review. Cancer Biol Ther. 2019;20(7):949-55.
  33. Nasser F, Motta Leal Filho JM, Affonso BB, et al. Liver Metastases in Pancreatic Acinar Cell Carcinoma Treated with Selective Internal Radiation Therapy with Y-90 Resin Microspheres. Case Reports Hepatol. 2017;2017:1-7.
  34. Sakakida T, Ishikawa T, Doi T, Morita R. Genomic landscape and clinical features of rare subtypes of pancreatic cancer: analysis with the national database of Japan. J Gastroenterol. 2023;58(6):575-85.
  35. Petrova E, Wellner J, Nording AK, et al. Survival Outcome and Prognostic Factors for Pancreatic Acinar Cell Carcinoma: Retrospective Analysis from the German Cancer Registry Group. Cancers (Basel). 2021;13(23):612.