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Journals / Medical Records / 2026 / Sayı: 1

Impact of Hemodialysis on Body Fluid Distribution and Phase Angle in Chronic Renal Failure: Insights from a Cross-Sectional Study

Kronik Böbrek Hastalığında Hemodiyalizin Vücut Sıvı Dağılımı ve Faz Açısı Üzerine Etkisi: Kesitsel Bir Çalışmadan Elde Edilen Bulgular

Hasan Esat Yücel(Kırşehir Ahi Evran University, Faculty of Medicine, Department of Internal Medicine)0000-0001-7788-0227
Tufan Ulcay(Kırşehir Ahi Evran University, Faculty of Medicine, Department of Anatomy)0000-0003-2203-3850
Ozkan Gorgulu(Kırşehir Ahi Evran University, Faculty of Medicine, Department of Biostatistics and Medical Informatics)0000-0002-6802-4450
Aydın Güçlü(Department of Nephrology, Kırşehir Training and Research Hospital)0000-0002-7853-2141
Ruken Öncü(Kırşehir Ahi Evran University, Faculty of Medicine, Department of Anatomy)0009-0001-4896-7822
Emre Uğuz(Kırşehir Ahi Evran University, Faculty of Medicine, Department of Anatomy)0000-0001-7813-3290
Muhammed Fırat Aladağ(Kırşehir Ahi Evran University, Faculty of Medicine, Department of Anatomy)0009-0005-5332-4783
Mesut Çeliker(Department of Internal Medicine, Kırşehir Training and Research Hospital)0000-0003-1240-657X
Kadirhan Doğan(Kapadokya University, College of Health Sciences)0000-0002-0249-1435
Mesut Sungur(Kırşehir Ahi Evran University, Faculty of Medicine, Department of Internal Medicine)0000-0002-2455-9824
Ahmet Uzun(Ondokuz Mayıs University, Faculty of Medicine, Department of Anatomy)0000-0003-4147-3798
Pages
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Publication Date
2026-03-21
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: HD leads to significant shifts in body fluid compartments, resulting in reduced hydration status and increased segmental phase angles values.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Bioelectrical impedance analysis (BIA) is a widely used, non-invasive technique that provides valuable information about phase angle (PhA) and hydration status, both of which are indicators of cellular health.
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Key Findings & Data:Using a multi-frequency (5, 50, 250 kHz) BIA device, segmental PhA and body fluid composition were measured.
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Conclusion & Impact:Conclusion: HD leads to significant shifts in body fluid compartments, resulting in reduced hydration status and increased segmental phase angles values.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Kronik böbrek yetmezliği · hemodiyaliz · faz açıları

Abstract

Aim: Bioelectrical impedance analysis (BIA) is a widely used, non-invasive technique that provides valuable information about phase angle (PhA) and hydration status, both of which are indicators of cellular health. In patients with chronic renal failure (CRF), fluid balance is often disrupted due to impaired kidney function. This study aimed to evaluate the effects of hemodialysis (HD) on segmental PhA values and body fluid distribution in patients with CRF. Material and Methods: Patients receiving HD for CRF were enrolled. Using a multi-frequency (5, 50, 250 kHz) BIA device, segmental PhA and body fluid composition were measured. Results: Post-dialysis measurements revealed a significant increase in phase angles across all examined segments. Concurrently, extracellular water (ECW), intracellular water (ICW) and total body water (TBW) volumes significantly decreased, whereas both ECW/TBW and ECW/ICW ratios increased. Conclusion: HD leads to significant shifts in body fluid compartments, resulting in reduced hydration status and increased segmental phase angles values.

Özet

Özet Giriş: Biyoelektrik empedans analizi (BIA), faz açısı (PhA) ve hidrasyon durumu hakkında değerli bilgiler sağlayan, yaygın olarak kullanılan, non-invaziv bir tekniktir. Bu iki parametre hücresel sağlığın göstergeleridir. Kronik böbrek yetmezliği (KBY) olan hastalarda, böbrek fonksiyonlarındaki bozulmaya bağlı olarak sıvı dengesi sıklıkla bozulur. Bu çalışma, KBY’li hastalarda hemodiyalizin (HD) segmental PhA değerleri ve vücut sıvı dağılımı üzerindeki etkilerini değerlendirmeyi amaçladı. Yöntem: KBY nedeniyle HD tedavisi alan hastalar çalışmaya dahil edildi. Çok frekanslı (5, 50, 250 kHz) BIA cihazı kullanılarak segmental PhA ve vücut sıvı kompozisyonu ölçümleri yapıldı. Bulgular: Diyaliz sonrası ölçümlerde, incelenen tüm segmentlerde faz açıları anlamlı şekilde arttı. Aynı zamanda hücre dışı sıvı (ECW), hücre içi sıvı (ICW) ve toplam vücut sıvısı (TBW) hacimleri anlamlı olarak azaldı; buna karşın ECW/TBW ve ECW/ICW oranlarında artış gözlendi. Sonuç: HD, vücut sıvı kompartmanlarında anlamlı değişimlere yol açarak hidrasyon durumunun azalmasına ve segmental faz açı değerlerinin artmasına neden olmaktadır.

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Cite This Article

Yücel, H. E., Ulcay, T., Gorgulu, O., Güçlü, A., Öncü, R., Uğuz, E., Aladağ, M. F., Çeliker, M., Doğan, K., Sungur, M., Uzun, A. (2026). Impact of Hemodialysis on Body Fluid Distribution and Phase Angle in Chronic Renal Failure: Insights from a Cross-Sectional Study. Medical Records, Sayı: 1. https://doi.org/10.37990/medr.1764330

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