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Journals / Çocuk ve Gençlik Ruh Sağlığı Dergisi / 2015 / Cilt: 22 - Sayı: 2

MASSIVE SERUM CREATINE KINASE ELEVATION DUE TO OLANZAPINE TREATMENT IN AN ADOLESCENT WITH BIPOLAR DISORDER

BİPOLAR BOZUKLUĞU OLAN BİR ERGENDE OLANZAPİN TEDAVİSİNE BAĞLI MASİF SERUM KREATİN KİNAZ YÜKSEKLİĞİ

CANAN TANIDIR
Tuğba ESEROĞLU
Sema BOZBEY
Hilal ADALETLİ
Özden Şükran ÜNERİ
Pages
125–129
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The mechanism of CK elevation due to antipsychotic use is not clear; however currently, when compared to cases like this presented one, it seems adequate to stop the antipsychotic medication and monitor serum CK levels periodically if other possible medical causes are excluded.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:There are case reports that indicate creatine kinase (CK) elevation due to atypical antipsychotic treatment in literature.
📊
Key Findings & Data:In this article we aimed to disscuss the clinical course, differential diagnosis and the mechanism of CK elevation in an adolescent with bipolar disorder whose serum CK levels increased to 32440 U/L (normal range: 30-200 U/L) after short-term olanzapine treatment.
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Conclusion & Impact:The mechanism of CK elevation due to antipsychotic use is not clear; however currently, when compared to cases like this presented one, it seems adequate to stop the antipsychotic medication and monitor serum CK levels periodically if other possible medical causes are excluded.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

There are case reports that indicate creatine kinase (CK) elevation due to atypical antipsychotic treatment in literature. In this article we aimed to disscuss the clinical course, differential diagnosis and the mechanism of CK elevation in an adolescent with bipolar disorder whose serum CK levels increased to 32440 U/L (normal range: 30-200 U/L) after short-term olanzapine treatment. The mechanism of CK elevation due to antipsychotic use is not clear; however currently, when compared to cases like this presented one, it seems adequate to stop the antipsychotic medication and monitor serum CK levels periodically if other possible medical causes are excluded.

Özet

Yazında atipik antipsikotiklere başlı serum kreatin kinaz (CK) deşerlerinin yükseldişini gösteren olgu sunumları mevcuttur. Bu yazıda kısa süreli olanzapin tedavisi sonrası serum CK deşeri 32440 U/L düzeyine (normal deşerler: 30-200 U/L) çıkan bipolar bozukluk tanılı ergen bir olgunun klinik seyrinin, ayırıcı tanısının ve CK yükselmesinin mekanizmasının tartıüılması amaçlanmıütır. Antipsikotiklere başlı CK yükselmesinin mekanizması net deşildir ancak bu gibi olgularla karüılaüıldışında, olabilecek dişer tıbbi sebepler dıülanmıüsa, ilacın kesilerek belirli aralıklarla kan deşerlerinin izlenmesi yeterli gibi görünmektedir.

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Cite This Article

TANIDIR, C., ESEROĞLU, T., BOZBEY, S., ADALETLİ, H., ÜNERİ, Ö. Ş. (2015). MASSIVE SERUM CREATINE KINASE ELEVATION DUE TO OLANZAPINE TREATMENT IN AN ADOLESCENT WITH BIPOLAR DISORDER. Çocuk ve Gençlik Ruh Sağlığı Dergisi, Cilt: 22 - Sayı: 2, 125–129. https://ajindex.com/articles/152445

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