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Journals / Journal of Medicine and Palliative Care / 2026 / Volume: 7 Issue: 4

Evaluation of the antibacterial effectiveness of fluoride toothpastes with added different herbal agents

Ömer Çellik(DICLE UNIVERSITY, FACULTY OF DENTISTRY)0000-0003-3514-930X
Savaş Sağmak(ADIYAMAN UNIVERSITY, FACULTY OF DENTISTRY)0000-0002-0082-6297
Sadık Akgün(ADIYAMAN UNIVERSITY, SCHOOL OF MEDICINE)0000-0002-1413-0450
Pages
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Publication Date
2026-08-15
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: The findings of this study suggest that the addition of natural agents, including miswak and Aloe vera, to fluoride toothpastes may contribute to improved antibacterial efficacy against cariogenic bacteria.

📌 3 Key Takeaways

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Objective & Hypothesis:Aims: The aim of this study was to examine the antibacterial effects on Streptococcus mutans (S. mutans) and Lactobacillus acidophilus (L. acidophilus) of commercially available fluoride toothpastes with two different concentrations of fluoride and different added herbal content (Aloe vera, miswak [Salvadora persica]).
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Key Findings & Data:Methods: In the study, which consisted of two fluoride toothpastes with different concentrations (700 ppm, 1450 ppm), two fluoride toothpastes with added natural content (Aloe vera, miswak), and a control group (chlorhexidine), the antimicrobial efficacy of the toothpastes was examined using the agar diffusion test at three different time points (1st, 3rd, and 5th days).
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Conclusion & Impact:Conclusion: The findings of this study suggest that the addition of natural agents, including miswak and Aloe vera, to fluoride toothpastes may contribute to improved antibacterial efficacy against cariogenic bacteria.
🔬Design:Research Article
📍Scope:20 samples
⚙️Variables:Toothpaste · antibacterial activity · fluoride

Abstract

Aims: The aim of this study was to examine the antibacterial effects on Streptococcus mutans (S. mutans) and Lactobacillus acidophilus (L. acidophilus) of commercially available fluoride toothpastes with two different concentrations of fluoride and different added herbal content (Aloe vera, miswak [Salvadora persica]). Methods: In the study, which consisted of two fluoride toothpastes with different concentrations (700 ppm, 1450 ppm), two fluoride toothpastes with added natural content (Aloe vera, miswak), and a control group (chlorhexidine), the antimicrobial efficacy of the toothpastes was examined using the agar diffusion test at three different time points (1st, 3rd, and 5th days). For each experimental group, a total of 20 samples were evaluated, comprising 10 samples inoculated with S. mutans (ATCC® 25175) and 10 samples inoculated with L. acidophilus (ATCC® 11975) standard bacterial isolates (n=10). Data were analyzed using repeated measures ANOVA and Bonferroni post hoc tests were applied for multiple comparisons. Statistical significance was set at (p<0.05). Results: Statistically significantly greater antimicrobial efficacy was determined in the groups with added herbal content compared to those without(p<0.05). The lowest effect against S. mutans was seen in the group with 700 ppm fluoride content and the lowest antimicrobial effect against L. acidophilus was determined in the toothpaste with 1450 ppm fluoride. Conclusion: The findings of this study suggest that the addition of natural agents, including miswak and Aloe vera, to fluoride toothpastes may contribute to improved antibacterial efficacy against cariogenic bacteria.

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Cite This Article

Çellik, Ö., Sağmak, S., Akgün, S. (2026). Evaluation of the antibacterial effectiveness of fluoride toothpastes with added different herbal agents. Journal of Medicine and Palliative Care, Volume: 7 Issue: 4. https://doi.org/10.47582/jompac.1937948

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