Journals / Journal of Health Sciences and Medicine / 2026 / Volume: 8 Issue: 4

Evaluation of chronic fatigue syndrome, depression, anxiety and somatization disorder individuals with a primary diagnosis of fibromyalgia

Primer fibromiyalji tanısı olan bireylerde kronik yorgunluk sendromu, depresyon, anksiyete ve somatizasyon bozukluğunun değerlendirilmesi

Canan Emiroğlu(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA DIŞKAPI YILDIRIM BEYAZIT SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0003-2543-4246
Nesrin Dilbaz(USKUDAR UNIVERSITY, SCHOOL OF MEDICINE)0000-0003-0724-3489
Pages
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Publication Date
2025-07-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Further research is needed to refine and evaluate the diagnostic criteria for both conditions.

📌 3 Key Takeaways

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Objective & Hypothesis:Aims: Currently, fibromyalgia (FM) is still diagnosed solely on clinical grounds, as no serologic, imaging, or histologic markers are available.
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Key Findings & Data:Methods: In this prospective, cross-sectional study, the prime MD scale was applied to 60 patients diagnosed with FM to investigate their overlap with psychiatric diagnoses.
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Conclusion & Impact:Further research is needed to refine and evaluate the diagnostic criteria for both conditions.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Fibromyalgia · fatigue · depression

Abstract

Aims: Currently, fibromyalgia (FM) is still diagnosed solely on clinical grounds, as no serologic, imaging, or histologic markers are available. Chronic fatigue syndrome (CFS) shares many similarities with FM. The implication of similar etiological factors and mechanisms, the overlap in symptoms and signs, and the high prevalence of psychiatric disorders such as anxiety, depression, panic attacks, and somatization disorder in both conditions have led to suggestions that they may represent different manifestations of the same disease. The primary objective of this investigation was to assess the prevalence of comorbid psychiatric conditions ‘including depression, anxiety, and somatization disorder’ as well as CFS, among individuals diagnosed with FM, and to explore potential overlaps in their clinical presentation. Methods: In this prospective, cross-sectional study, the prime MD scale was applied to 60 patients diagnosed with FM to investigate their overlap with psychiatric diagnoses. In addition, patients were evaluated according to the Fukuda Classification System to determine whether they could be diagnosed with CFS. Results: The incidence rate of anxiety disorder was 33.3% and the incidence rate of somatoform disorder was 83.4%. Major depression was detected in 10 patients (16.7%) and dysthymia in 16 patients. Eight out of 60 patients (13.3%) did not have any psychiatric disorders, while the remaining 52 patients had at least one disorder or more than one disorder. Although 50 of 60 patients (83.3%) complained of fatigue, only 8 (13.3%) patients were diagnosed by meeting sufficient criteria for CFS. Conclusion: Although FM and CFS are not the same clinical entity, they appear to be two conditions with overlapping symptoms, particularly psychiatric ones, which frequently coexist. The prevalence of psychiatric symptoms and diagnoses was notably higher among individuals who met the diagnostic criteria for both FM and CFS. Further research is needed to refine and evaluate the diagnostic criteria for both conditions.

Özet

Giriş: Kronik yaygın ağrı, dünya genelinde yetişkinlerin %10 ila %15'ini etkilemektedir ve bunların çoğunda fibromiyalji (FM) bulunmaktadır. FM genel popülasyonda oldukça yaygın bir sendromdur ve bel ağrısı ve osteoartritten sonra üçüncü en yaygın kas-iskelet sistemi rahatsızlığıdır. Günümüzde, serolojik, görüntüleme veya histolojik belirteçler mevcut olmadığından, FM tanısı hala sadece klinik olarak konulmaktadır. Kronik Yorgunluk Sendromu birçok açıdan PFS'ye benzemektedir. Etiyolojilerinde benzer faktör ve mekanizmaların suçlanması, aynı semptom ve bulguların birlikte görülmesi ve her iki hastalıkta da anksiyete, depresyon, panik atak ve somatizasyon bozukluğu gibi psikiyatrik bozuklukların yüksek prevalansı, bu iki durumun aynı hastalığın farklı tezahürleri olabileceği iddialarına yol açmıştır. Amaç: Bu araştırmanın amacı, PFS tanısı almış kişilerde kronik yorgunluk sendromu (KYS) ile birlikte depresyon, anksiyete ve somatizasyon bozukluğu gibi komorbid psikiyatrik durumların yaygınlığını değerlendirmek ve klinik sunumdaki potansiyel örtüşmeyi incelemektir. Materyal ve metod: Bu prospektif, kesitsel çalışmada, psikiyatrik tanılarla örtüşmelerini araştırmak için PFS tanısı alan 60 hastaya Prime MD ölçeği uygulanmıştır. Ayrıca, hastalar KFS tanısı alıp alamayacaklarını belirlemek için Fukuda Sınıflandırma Sistemine göre değerlendirilmiştir. Bulgular: Anksiyete bozukluğu görülme oranı %33,3 ve somatoform bozukluk görülme oranı %83,4 idi. Majör depresyon 10 hastada (%16.7) ve distimi 16 hastada saptandı. 60 hastanın sekizinde (%13,3) herhangi bir psikiyatrik bozukluk bulunmazken, geri kalan 52 hastada en az bir veya birden fazla bozukluk vardı. 60 hastanın 50'si (%83,3) yorgunluktan şikayetçi olmasına rağmen, sadece 8 (%13,3) hasta KYS için yeterli kriterleri karşılayarak tanı almıştır. Sonuç: PFS ve KYS aynı klinik antite olmamakla birlikte, benzer semptomların örtüştüğü iki klinik durum gibi görünmektedir, özellikle psikiyatrik semptomlar ve durumlar sıklıkla bir arada bulunmaktadır. Psikiyatrik belirti ve tanıların yaygınlığının, özellikle hem PFS hem de KYS tanı kriterlerini karşılayan bireyler arasında yüksek olduğu görülmüştür.

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Cite This Article

Emiroğlu, C., Dilbaz, N. (2025). Evaluation of chronic fatigue syndrome, depression, anxiety and somatization disorder individuals with a primary diagnosis of fibromyalgia. Journal of Health Sciences and Medicine, Volume: 8 Issue: 4. https://doi.org/10.32322/jhsm.1689609

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