Journals / Journal of Health Sciences and Medicine / 2025 / Volume: 8 Issue: 6

Evaluation of the MAPH score in predicting acute ischemic stroke severity and major vessel occlusion in the emergency department

Acil serviste akut iskemik inme şiddeti ve majör damar oklüzyonunu öngörmede MAPH skorunun değerlendirilmesi

Emine Sarcan(Ankara Etlik City Hastanesi, Emergency Medicine Department)0000-0002-5789-9622
Merve Yazla(Ankara Etlik City Hastanesi, Emergency Medicine Department)0000-0002-4092-4633
Pages
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Publication Date
2025-10-25
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: The MAPH score is a simple and practical tool that aids in distinguishing AIS from TIA and predicting major vessel occlusion, thus improving stroke management in emergency settings.

📌 3 Key Takeaways

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Objective & Hypothesis:Aims: This study aimed to evaluate the utility of the MAPH score, a biomarker combining blood viscosity indicators such as mean platelet volume (MPV), total protein, and hematocrit, in differentiating acute ischemic stroke (AIS) from transient ischemic attack (TIA) and predicting major vessel occlusion in patients presenting to the emergency department with suspected stroke.
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Key Findings & Data:Methods: A retrospective analysis was conducted on 226 patients presenting to the emergency department with focal neurological symptoms.
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Conclusion & Impact:Conclusion: The MAPH score is a simple and practical tool that aids in distinguishing AIS from TIA and predicting major vessel occlusion, thus improving stroke management in emergency settings.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:MAPH score · acute ischemic stroke · transient ischemic attack

Abstract

Aims: This study aimed to evaluate the utility of the MAPH score, a biomarker combining blood viscosity indicators such as mean platelet volume (MPV), total protein, and hematocrit, in differentiating acute ischemic stroke (AIS) from transient ischemic attack (TIA) and predicting major vessel occlusion in patients presenting to the emergency department with suspected stroke. Methods: A retrospective analysis was conducted on 226 patients presenting to the emergency department with focal neurological symptoms. Patients were categorized into AIS and TIA groups based on diffusion-weighted magnetic resonance imaging findings. Data collected included demographic characteristics, vital signs, laboratory parameters, and imaging results. MPV, age, hematocrit, and total protein levels were recorded. High-shear rate and low-shear rate were calculated from total protein and hematocrit values. ROC curve analysis was performed to evaluate diagnostic performance Results: The ROC analysis demonstrated the diagnostic accuracy of the MAPH score in differentiating AIS from TIA and predicting major vessel occlusion. Additionally, the score showed a significant correlation with NIHSS ≥20, indicating its association with stroke severity. Conclusion: The MAPH score is a simple and practical tool that aids in distinguishing AIS from TIA and predicting major vessel occlusion, thus improving stroke management in emergency settings.

Özet

Amaç: Bu çalışma, ortalama trombosit hacmi (MPV), total protein ve hematokrit gibi kan viskozite göstergelerini birleştiren bir biyobelirteç olan MAPH skorunun, akut iskemik inme (Aİİ) ile geçici iskemik atak (GİA) ayrımında ve acil servise inme şüphesi ile başvuran hastalarda majör damar oklüzyonunu öngörmedeki değerini değerlendirmeyi amaçladı. Yöntem: Acil servise fokal nörolojik semptomlarla başvuran 226 hasta üzerinde retrospektif bir analiz yapıldı. Difüzyon ağırlıklı manyetik rezonans görüntüleme bulgularına göre hastalar Aİİ ve GİA gruplarına ayrıldı. Demografik özellikler, vital bulgular, laboratuvar parametreleri ve görüntüleme sonuçları kaydedildi. MPV, yaş, hematokrit ve total protein düzeyleri belirlendi. Total protein ve hematokrit değerlerinden yüksek kayma hızı ve düşük kayma hızı hesaplandı. Tanısal performansı değerlendirmek için ROC eğrisi analizi yapıldı. Bulgular: ROC analizi, MAPH skorunun Aİİ ile GİA ayrımındaki ve majör damar oklüzyonunu öngörmedeki tanısal doğruluğunu gösterdi. Ayrıca skorun NIHSS ≥ 20 ile anlamlı bir korelasyon gösterdiği, bu nedenle inme şiddeti ile ilişkili olduğu saptandı. Sonuç: MAPH skoru, Aİİ ile GİA’nın ayırt edilmesine ve majör damar oklüzyonunun öngörülmesine yardımcı olan, basit ve pratik bir araç olup acil servis koşullarında inme yönetimini geliştirmektedir.

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Cite This Article

Sarcan, E., Yazla, M. (2025). Evaluation of the MAPH score in predicting acute ischemic stroke severity and major vessel occlusion in the emergency department. Journal of Health Sciences and Medicine, Volume: 8 Issue: 6. https://doi.org/10.32322/jhsm.1774461

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