Journals / Journal of Contemporary Medicine / 2026 / Cilt: 5 Sayı: 1-Ek

Lethal Colchicine Intoxication

Öldürücü Kolşisin Zehirlenmesi

Pages
100–27
Publication Date
2015-04-09
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Herein, we reported a case of colchicine overdose for suicide attempt.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Colchicine is a well-recognized drug, that is used for the treatment of familial Mediterranean Fever, acute gout arthritis, amyloidosis and primary biliary cirrhosis.
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Key Findings & Data:Colchicine is an alkaloid drug that is derived from Colchium autumnale.Diarrhea, sickness, vomiting, abdominal pain, excessive deficiency of electrolytes and fluid are common symptoms of intoxication due to higher absorption of colchicine from gastrointestinal surface.
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Conclusion & Impact:Herein, we reported a case of colchicine overdose for suicide attempt.
🔬Design:Makale
📍Scope:Comprehensive Sample
⚙️Variables:kolşisin zehirlenmesi · intihar · öldürücü

Abstract

Colchicine is a well-recognized drug, that is used for the treatment of familial Mediterranean Fever, acute gout arthritis, amyloidosis and primary biliary cirrhosis. Colchicine is an alkaloid drug that is derived from Colchium autumnale.Diarrhea, sickness, vomiting, abdominal pain, excessive deficiency of electrolytes and fluid are common symptoms of intoxication due to higher absorption of colchicine from gastrointestinal surface. Colchicine has a narrow therapeutic index and suicide attempted with this drug has a higher mortality.Colchicine intoxication is a critical and life-threatening condition for patients so that pyhsicians should be aware of over dose and complications of this drug. Herein, we reported a case of colchicine overdose for suicide attempt.

Özet

Kolşisin Ailevi Akdeniz Ateşi, amiloidoz, akut gut artriti ve primer bilier siroz tedavisinde kullanılan iyi bilinen bir ilaçtır. Kolşisin, Colchium Autumnale bitkisinden elde edilen alkaloid bir ilaçtır. İshal, bulantı, kusma, karın ağrısı, elektrolit ve sıvının aşırı kaybı gastrointestinal yüzeyden aşırı emilen kolşisinin zehirlenme bulgularıdır. Kolşisin dar bir töropetik indekse sahip olduğundan bu ilaç ile intihar girişimi yüksek bir mortaliteye sahiptir. Kolşisin zehirlenmesi hasta için kritik ve hayatı tehdit edici olduğundan doktorlar, bu ilacın komplikasyonlarını ve aşırı doz alımında ortaya çıkacacak etkilerin farkında olmalıdır. Burada, intihar girişimi ile yüksek doz kolşisin alan bir olguyu sunmayı amaçladık

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Cite This Article

Genç, S., Avcı, S., Höke, M., Terzi, S., Özkan, S. (2015). Lethal Colchicine Intoxication. Journal of Contemporary Medicine, Cilt: 5 Sayı: 1-Ek, 100–27. https://doi.org/10.16899/ctd.51099

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