Journals / Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi / 2020 / Cilt: 33 - Sayı: 1

Cognitive functions in opioid-dependent males according to duration of abstinence

Pages
50–58
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therefore, prospective studies and animal studies in which the effect of opioids can be examined exclusively are needed

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Opioid dependence is a neurobehavioral disorder characterized by repeated compulsive craving or using an opioid.
📊
Key Findings & Data:In this study, we aimed to evaluate cognitive functions according to the duration of abstinence and other factors affecting cognitive functions.Method: The study was carried out between February and April 2017 at the Psychiatry Department of Gazi University Medical Faculty.
💡
Conclusion & Impact:Therefore, prospective studies and animal studies in which the effect of opioids can be examined exclusively are needed
🔬Design:Research Article
📍Scope:2017 Verileri
⚙️Variables:Domain Parameters

Özet

Objective: Opioid dependence is a neurobehavioral disorder characterized by repeated compulsive craving or using an opioid. In this study, we aimed to evaluate cognitive functions according to the duration of abstinence and other factors affecting cognitive functions.Method: The study was carried out between February and April 2017 at the Psychiatry Department of Gazi University Medical Faculty. A total of 96 adult males participated; all of them had received detoxification treatment and were undergoing maintenance treatment. Patients were divided into three groups according to the duration of abstinence. First, a sociodemographic data form and Beck Anxiety Inventory were administered. Afterwards, the Wisconsin Card Sorting Test, Rey Auditory-Verbal Learning Test, and Stroop Test were applied.Results: The sample group showed no significant impairment in their cognitive functions when compared to the norm values. The group of patients with 0-3 months of abstinence had higher memory scores than those who had been abstinent for more than 1 year. We also found that duration of multiple substance use, age of first substance use, and the number of treatments undergone affected some of the cognitive functions negatively.Conclusion: This study is the first in which cognitive functions have been evaluated in opioid-dependent males in Turkey. It is not possible to control all of the factors affecting cognitive functions. Therefore, prospective studies and animal studies in which the effect of opioids can be examined exclusively are needed

🔖

Cite This Article

KOPARAL, B., YANİK, C. O., SAHİNER, I. V., KALOGLU, H. A., AKSU, M. H., UTKU, C., ARİKAN, Z. (2020). Cognitive functions in opioid-dependent males according to duration of abstinence. Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi, Cilt: 33 - Sayı: 1, 50–58. https://ajindex.com/articles/150630

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Sadock BJ, Sadock VA, Ruiz P. Kaplan & Sadock’s Synopsis of Psychiatry: Behavioral Science/Clinical Psychiatry. Bozkurt A (Translation Editor) Eleventh ed., Ankara: Gunes Kitabevi, 2016, 659-666. (Turkish
  2. Turkey Drug Report – Data for 2016. Ankara: Turkish Drug and Drug Addiction Monitoring Center, 2017. (Turkish
  3. United Nations Office on Drugs and Crime. World Drug Report 2016. New York: United Nations, 2016
  4. Bukten A, Skurtveit S, Gossop M, Waal H, Stangeland P, Havnes I, et al. Engagement with opioid maintenance treatment and reductions in crime: a longitudinal national cohort study. Addiction 2012; 107:393-399
  5. Mattick RP, Breen C, Kimber J, Davoli M. Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence. Cochrane Database Syst Rev 2009:CD002209
  6. Lezak MD. Neuropsychological Assessment. Oxford: Oxford University Press, 1995
  7. Pennington BF, Ozonoff S. Executive functions and developmental psychopathology. J Child Psychol Psychiatry 1996; 37:51-87
  8. Ersche KD, Sahakian BJ. The neuropsychology of amphetamine and opiate dependence: implications for treatment. Neuropsychol Rev 2007; 17:317-336
  9. Baldacchino A, Balfour DJ, Passetti F, Humphris G, Matthews K. Neuropsychological consequences of chronic opioid use: a quantitative review and meta-analysis. Neurosci Biobehav Rev 2012; 36:2056-2068
  10. Soyka M. Cognitive Functioning in Methadone Use; In Preedy V (editor). Neuropathology of Drug Addictions and Substance Misuse. Amsterdam: Elsevier (Academic Press), 2016, Vol. 3, 603-607
  11. Fields FR, Fullerton JR. Influence of heroin addiction on neuropsychological functioning. J Consult Clin Psychol 1975; 43:114
  12. Li X, Zhang F, Zhou Y, Zhang M, Wang X, Shen M. Decision-making deficits are still present in heroin abusers after short- to long-term abstinence. Drug Alcohol Depend 2013; 130:61-67
  13. Fishbein DH, Krupitsky E, Flannery BA, Langevin DJ, Bobashev G, Verbitskaya E, et al. Neurocognitive characterizations of Russian heroin addicts without a significant history of other drug use. Drug Alcohol Depend 2007; 90:25-38
  14. Ornstein TJ, Iddon JL, Baldacchino AM, Sahakian BJ, London M, Everitt BJ, et al. Profiles of cognitive dysfunction in chronic amphetamine and heroin abusers. Neuropsychopharmacology 2000; 23:113-126
  15. Fernandez-Serrano MJ, Perez-Garcia M, Verdejo-Garcia A. What are the specific vs. generalized effects of drugs of abuse on neuropsychological performance? Neurosci Biobehav