Journals / Adli Tıp Bülteni / 2017 / Cilt: 22 - Sayı: 2

Velvet Heart: Systemic Fungal Infection Accompanying with Cardiac Involvement and Review of the Literature

Kadife Kalp: Kalp Tutulumunun Eşlik Ettiği Sistemik Mantar Enfeksiyonu ve Literatürün Gözden Geçirilmesi

Pages
134–139
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Besides, this report aims to draw attention to systemic infectious diseases that can be found at autopsies of persons who had used illicit drugs and it is intended to review the measures for the protection of the autopsy personnel.

📌 3 Key Takeaways

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Objective & Hypothesis:Injuries and intoxications are frequent cause of deaths in illicit drug users.
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Key Findings & Data:Drug abuse is also associated with increase in infectious diseases and decreased level of immunity.
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Conclusion & Impact:Besides, this report aims to draw attention to systemic infectious diseases that can be found at autopsies of persons who had used illicit drugs and it is intended to review the measures for the protection of the autopsy personnel.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Injuries and intoxications are frequent cause of deaths in illicit drug users. Drug abuse is also associated with increase in infectious diseases and decreased level of immunity. Especially collective usage of syringes can be remarkably dangerous. It is difficult to diagnose the fungal infections in people whose immune systems are deficient and spreading of the pathogenic microorganisms through the bloodstream can lead to systemic infections which can cause rapid death.In this article, a case of a 45-year-old man is being presented who died due to illicit drug intoxication. Apparent cardiac involvement with systemic fungal infection has been determined at the autopsy. The case has been evaluated with the literature. The skin and cardiac findings of the case are both rare and educational. Besides, this report aims to draw attention to systemic infectious diseases that can be found at autopsies of persons who had used illicit drugs and it is intended to review the measures for the protection of the autopsy personnel.

Özet

Madde bağımlılarında yaralanmalar ve zehirlenmeler sıklıkla görülen ölüm nedenleridir. Ayrıca madde bağımlılığı, artmış enfeksiyon sıklığı ve azalmış immünite ile de ilişkilendirilmektedir. Özellikle ortak enjektör kullanımı kan yoluyla bulaşan enfeksiyonlar açısından ciddi tehlike yaratmaktadır. Bağışıklık sistemi yetersiz olan kişilerde, mantar enfeksiyonlarının teşhisi güç olabilmekte ve etkenin kan dolaşımı ile yayılımı, hızla ölüme neden olan sistemik enfeksiyona yol açabilmektedir. Olgularda nadiren kalp tutulumu da görülebilmektedir.Bu sunumda; uyutucu ve uyuşturucu madde zehirlenmesine bağlı ölen 45 yaşında erkek olgu aktarılmaktadır. Otopside belirgin kalp tutulumu gösteren sistemik mantar enfeksiyonu saptanmıştır. Olgu, kaynaklar eşliğinde değerlendirilmiştir. Olguya ait cilt ve kalp bulguları hem ender rastlanan hem de eğitici nitelikte bulgulardır. Bunların yanında makale, madde bağımlılarının otopsilerinde rastlanabilecek sistemik enfeksiyon hastalıklarına dikkati çekmeyi ve otopsi ekibinin korunmasına yönelik önlemleri gözden geçirmeyi amaçlamaktadır.

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Cite This Article

DEMİRÇİN, S., DİROL, F., KARAGÖZ, Y. M., BULGUR, D. K., GÖRAL, P., AKSOY, K. A. (2017). Velvet Heart: Systemic Fungal Infection Accompanying with Cardiac Involvement and Review of the Literature. Adli Tıp Bülteni, Cilt: 22 - Sayı: 2, 134–139. https://ajindex.com/articles/148952

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References (5)

  1. United Nations Office on Drugs and Crime (UNODC). World Drug Report 2014. United Nations Publication, New York, 2014:3, 6
  2. Turkish Monitoring Center For Drugs and Drug Addiction (TUBİM). National Report of EMCDDA, 2013. KOM Publishing, 2013:95
  3. Jönsson AK, Holmgren P, Druid H, Ahlner J. Cause of death and drug use pattern in deceased drug addicts in Sweden, 2002-2003. Forensic Science International, 2007;169:101- 107. doi: 10.1016/j.forsciint.2006.08.002 4. World Health Organization. Guidance on prevention of viral hepatitis B and C among people who inject drugs. WHO Press, Genova, 2012:13
  4. Thiene G, Basso C. Pathology and pathogenesis of infective endocarditis in native heart valves. Cardiovascular Pathology, 2006;15:256-263. doi: 10.1016/j.carpath.2006.05.009 6. Inabo HI. The relationship between drug abuse and microbial infections. African Journal of Biotechnology, 2005;13 (4):1588-1590
  5. Cabral GA, Pettit DAD. Drugs and immunity: cannabinoids and their role in decreased resistance to infectious disease. Journal of Neuroimmunology, 1998;83:116-123. doi: 10.1016/S0165-5728(97)00227-0 8. Neri S, Bruno CM, Pulvirenti D, Malaguarnera M, Italiano C, Mauceri B et al. Randomized clinical trial to compare the effects of methadone and buprenorphine on the immune system in drug abusers. Psychopharmacology, 2005;179:700- 704. doi: 10.1007/s00213-005-2239-x 9. Dignani MC. Epidemiology of invasive fungal diseases on the basis of autopsy reports. F1000 Prime Reports, 2014;6:81. doi:10.12703/P6-81 doi: 10.12703/P6-81 10. Chinena K, Tokudab Y, Sakamotoa A, Fujiokaa Y. Fungal infections of the heart: A clinicopathologic study of 50 autopsy cases. Pathology - Research and Practice, 2007;203:705-715. doi:10.1016/j.prp.2007.06.008 11. Ohya İ, Bunai Y, Tsujinaka M, Akaza K, Nakamura I. Fatal Aspergillus pancarditis after incompatible blood transfusion intended to be an autologous blood transfusion. Legal Medicine, 2000;13:246-251. doi: 10.1016/S1344- 6223(01)00037-2 12. Santiago TMG, Pritt B, Gibson L E, Comfere N I. Diagnosis of deep cutaneous fungal infections: Correlation between skin tissue culture and histopathology. Journal of American Academy of Dermatology, 2014;71:293-301. doi: 10.1016/j.jaad.2014.03.042 13. Hardin NJ, Infection control at autopsy: a guide for pathologists and autopsy personel. Current Diagnostic Pathology, 2000;6: 75-83. doi: 10.1054/cdip.2000.0021 14. Mazuchowski EL, Meier PA. The Modern Autopsy: What to do if infection is suspected