Journals / Gazi Sağlık Bilimleri Dergisi / 2026 / Cilt: 11 Sayı: 2

THE RELATIONSHIP BETWEEN DISEASE-RELATED KNOWLEDGE AND DISEASE ACTIVITY, FUNCTION, QUALITY OF LIFE, FEAR, EMOTIONAL STATUS, AND SELF-EFFICACY IN PATIENTS WITH ANKYLOSING SPONDYLITIS: A CROSS-SECTIONAL STUDY

ANKİLOZAN SPONDİLİTLİ HASTALARDA HASTALIĞA İLİŞKİN BİLGİ DÜZEYİ İLE HASTALIK AKTİVİTESİ, FONKSİYON, YAŞAM KALİTESİ, KORKU, DUYGUSAL DURUM VE ÖZ-YETERLİLİK ARASINDAKİ İLİŞKİ: KESİTSEL BİR ÇALIŞMA

Pages
117–128
Publication Date
2026-08-31
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Greater disease-related knowledge was associated with lower disease activity, fewer depressive symptoms, and higher self-efficacy, but also with greater functional impairment and poorer disease-specific quality of life.

📌 3 Key Takeaways

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Objective & Hypothesis:Background: Disease-related knowledge may support self-management in chronic inflammatory rheumatic diseases.
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Key Findings & Data:Method: This single-center cross-sectional study included 139 patients with AS.
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Conclusion & Impact:Conclusion: Greater disease-related knowledge was associated with lower disease activity, fewer depressive symptoms, and higher self-efficacy, but also with greater functional impairment and poorer disease-specific quality of life.
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Ankilozan spondilit · Hastalığa ilişkin bilgi · Yaşam kalitesi

Abstract

Background: Disease-related knowledge may support self-management in chronic inflammatory rheumatic diseases. Aim: This study examined associations between disease-related knowledge and clinical and psychosocial outcomes in patients with ankylosing spondylitis (AS). Method: This single-center cross-sectional study included 139 patients with AS. Disease-related knowledge was assessed using the AS Knowledge Questionnaire. Associations were examined using Pearson correlations and adjusted partial correlations. Partial correlations controlled for educational level, age, sex, disease duration, regular medication use, regular exercise, and disease activity, except when disease activity was the outcome. Bonferroni correction was applied separately to seven prespecified associations in both analyses. Results: Mean age was 43.1 ± 12.1 years; 54.0% were male, and the mean disease-related knowledge score was 16.2 ± 4.5. After adjustment, disease-related knowledge was weakly and negatively correlated with disease activity (partial r = -0.34), moderately and positively correlated with functional impairment (partial r = 0.40), poorer disease-specific quality of life (partial r = 0.42), and self-efficacy (partial r = 0.53), and moderately and negatively correlated with depression (partial r = -0.50); all remained significant at p < 0.007. Associations with disease-related fear and anxiety were not significant after correction. Conclusion: Greater disease-related knowledge was associated with lower disease activity, fewer depressive symptoms, and higher self-efficacy, but also with greater functional impairment and poorer disease-specific quality of life.

Özet

Giriş: Hastalığa ilişkin bilgi, kronik inflamatuar romatizmal hastalıklarda öz-yönetimi destekleyebilir. Amaç: Bu çalışma, ankilozan spondilitli (AS) hastalarda hastalığa ilişkin bilgi ile klinik ve psikososyal sonuçlar arasındaki ilişkileri incelemiştir. Yöntem: Bu tek merkezli kesitsel çalışmaya 139 AS hastası dahil edildi. Hastalığa ilişkin bilgi AS Bilgi Anketi ile değerlendirildi. Hastalık aktivitesi, fonksiyon, hastalığa özgü yaşam kalitesi, hastalıkla ilişkili korku, anksiyete, depresyon ve öz-yeterlilik ile ilişkiler; eğitim düzeyi, yaş, cinsiyet, hastalık süresi, düzenli ilaç kullanımı, düzenli egzersiz ve hastalık aktivitesi kontrol edilerek Pearson ve düzeltilmiş kısmi korelasyonlarla incelendi. Bonferroni düzeltmesi, her iki analizde önceden belirlenen yedi ilişkiye ayrı ayrı uygulandı. Bulgular: Yaş ortalaması 43,1 ± 12,1 yıl olup katılımcıların %54.0'ı erkekti; hastalığa ilişkin bilgi puanı ortalaması 16,2 ± 4,5 idi. Düzeltme sonrasında hastalığa ilişkin bilgi; hastalık aktivitesi ile zayıf negatif (kısmi r = -0,34), fonksiyonel kısıtlılık (kısmi r = 0,40), daha kötü hastalığa özgü yaşam kalitesi (kısmi r = 0,42) ve öz-yeterlilik (kısmi r = 0,53) ile orta düzeyde pozitif, depresyon ile orta düzeyde negatif (kısmi r = -0,50) korelasyon gösterdi; tümü p < 0.007 düzeyinde anlamlı kaldı. Hastalıkla ilişkili korku ve anksiyete ile ilişkiler düzeltme sonrasında anlamlı değildi. Sonuç: Daha yüksek hastalığa ilişkin bilgi; daha düşük hastalık aktivitesi, daha az depresif belirti ve daha yüksek öz-yeterlilik ile, ancak aynı zamanda daha fazla fonksiyonel kısıtlılık ve daha kötü hastalığa özgü yaşam kalitesi ile ilişkiliydi.

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Cite This Article

Tore, N. G., Pala, G. G., Bayram, S., Yıldırım, D., Oskay, D. (2026). THE RELATIONSHIP BETWEEN DISEASE-RELATED KNOWLEDGE AND DISEASE ACTIVITY, FUNCTION, QUALITY OF LIFE, FEAR, EMOTIONAL STATUS, AND SELF-EFFICACY IN PATIENTS WITH ANKYLOSING SPONDYLITIS: A CROSS-SECTIONAL STUDY. Gazi Sağlık Bilimleri Dergisi, Cilt: 11 Sayı: 2, 117–128. https://ajindex.com/articles/1486342

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