Evaluation of WBC, RDW and MPV Rates in the First Blood of Patients Admitted to the Emergency Department with Gastrointestinal System Bleeding

Abstract

Gastrointestinal system (GI) bleeding is emergency intervention required situation and important problem due to mortality, morbidity and hospitalization costs(1). Despite the progress in diagnosis and treatment,upper GI bleeding has 2-10% mortality rate, thus since 1960, desired improvement could not be achieved (1, 2). Therefore, evaluation, diagnosis and treatment approaches of patients with upper GI-bleeding have a special importance. The severity ranges covers between; subclinical hidden bleeding to occult bleeding, from chronic anemia to acute hypovolemic shock(3)White blood cells, also known as leukocytes (WBC), are immune system fighters and migrate to the side of all kinds of infections and inflammation.They are the main cells that cause inflammation. Leukocyte count (WBC): 4,500 to 10000 cells / mcL. Average Platelet volume (MPV) is the laboratory finding which shows platelet activation. It is one of the simple subclinical inflammation marker. A red cell distribution width (RDW)reflecting the variability in the size of circulating erythrocytes and is often used as indicator for the diagnosis of anemia(4). However, systemic inflammations, chronic nutritional disorders, ineffective erythropoiesis diagnosis and in bone marrow dysfunction RDW values may also increase. (5) In our study, retrospectively, between January 2020-March 2020, patients with Gastrointestinal system (GI) bleeding as the primary diagnosis,the age range between 18-75 years old and whose blood hemograms were studied were included.WBC, RDW and MPV values are proportioned.