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Journals / Black Sea Journal of Health Science / 2025 / Cilt: 8 Sayı: 6

The Effect of Trichodoll® Application on Serum Trace Element Profile in Young Holstein Cattle with Trichophytosis

Mehmet Nesip Çelik(DİCLE ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ, VETERİNER PR.)0009-0000-0757-0637
Ömer Faruk Katanalp(DİCLE ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ)0000-0003-3353-1871
Enes Arıca(DİCLE ÜNİVERSİTESİ)0000-0002-8663-4826
Almina Güneş(DICLE UNIVERSITY)0000-0002-5542-2345
Lale Çivi(DICLE UNIVERSITY)0009-0002-7461-5617
Hasan İçen(DICLE UNIVERSITY)0000-0002-6034-3203
Pages
290–295
Publication Date
2025-11-15
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Trace elements play a critical role in maintaining immune function, antioxidant defense, and overall metabolic balance during infectious diseases.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Trichophytosis is a contagious and zoonotic fungal skin disease that primarily affects keratinized tissues such as hair and epidermis, leading to economic losses in cattle production and posing public health concerns.
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Key Findings & Data:A total of 40 young Holstein cattle, aged 4–18 months, were included in the study and divided into two groups: healthy controls (Group I; n=20) and young Holstein cattle with trichophytosis (Group II; n=20).
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Conclusion & Impact:Trace elements play a critical role in maintaining immune function, antioxidant defense, and overall metabolic balance during infectious diseases.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Serum profile · Trace elements · Trichophytosis

Abstract

Trichophytosis is a contagious and zoonotic fungal skin disease that primarily affects keratinized tissues such as hair and epidermis, leading to economic losses in cattle production and posing public health concerns. Trace elements play a critical role in maintaining immune function, antioxidant defense, and overall metabolic balance during infectious diseases. The present study aimed to evaluate the effects of TrichoDoll® vaccination on serum trace element concentrations, including zinc (Zn), copper (Cu), selenium (Se), cobalt (Co), and manganese (Mn), in naturally infected young Holstein cattle with trichophytosis. A total of 40 young Holstein cattle, aged 4–18 months, were included in the study and divided into two groups: healthy controls (Group I; n=20) and young Holstein cattle with trichophytosis (Group II; n=20). Blood samples were collected from infected young Holstein cattle before vaccination (day 0) and after vaccination (day 28). Serum trace element levels were measured and compared within and between groups. In Group I, mean serum levels of Mn, Co, Cu, Zn, and Se were 17.28, 0.97, 583.66, 802.66, and 37.14 ppb, respectively. In Group II, pre-vaccination means were 13.11, 3.32, 832.05, 871.08, and 41.50 ppb, while post-vaccination values were 17.49, 2.52, 810.34, 759.21, and 37.37 ppb, respectively. The results demonstrated that TrichoDoll® vaccination induced significant alterations in serum trace element concentrations, particularly in Mn, Co, and Zn, suggesting a modulatory effect on metabolic and immune-related pathways. These findings highlight the potential role of trace element balance in the pathogenesis of trichophytosis and in shaping the host response to vaccination. Further investigations are warranted to elucidate the underlying mechanisms and to determine whether targeted trace element supplementation could enhance treatment outcomes.

Özet

Trichophytosis is a contagious and zoonotic fungal skin disease that primarily affects keratinized tissues such as hair and epidermis, leading to economic losses in cattle production and posing public health concerns. Trace elements play a critical role in maintaining immune function, antioxidant defense, and overall metabolic balance during infectious diseases. The present study aimed to evaluate the effects of TrichoDoll® vaccination on serum trace element concentrations, including zinc (Zn), copper (Cu), selenium (Se), cobalt (Co), and manganese (Mn), in naturally infected young Holstein cattle with trichophytosis. A total of 40 young Holstein cattle, aged 4–18 months, were included in the study and divided into two groups: healthy controls (Group I; n=20) and young Holstein cattle with trichophytosis (Group II; n=20). Blood samples were collected from infected young Holstein cattle before vaccination (day 0) and after vaccination (day 28). Serum trace element levels were measured and compared within and between groups. In Group I, mean serum levels of Mn, Co, Cu, Zn, and Se were 17.28, 0.97, 583.66, 802.66, and 37.14 ppb, respectively. In Group II, pre-vaccination means were 13.11, 3.32, 832.05, 871.08, and 41.50 ppb, while post-vaccination values were 17.49, 2.52, 810.34, 759.21, and 37.37 ppb, respectively. The results demonstrated that TrichoDoll® vaccination induced significant alterations in serum trace element concentrations, particularly in Mn, Co, and Zn, suggesting a modulatory effect on metabolic and immune-related pathways. These findings highlight the potential role of trace element balance in the pathogenesis of trichophytosis and in shaping the host response to vaccination. Further investigations are warranted to elucidate the underlying mechanisms and to determine whether targeted trace element supplementation could enhance treatment outcomes.

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Cite This Article

Çelik, M. N., Katanalp, Ö. F., Arıca, E., Güneş, A., Çivi, L., İçen, H. (2025). The Effect of Trichodoll® Application on Serum Trace Element Profile in Young Holstein Cattle with Trichophytosis. Black Sea Journal of Health Science, Cilt: 8 Sayı: 6, 290–295. https://doi.org/10.19127/bshealthscience.1798132

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