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Journals / Aydın Dental Journal / 2026 / Cilt: 10 Sayı: 2

Dentinogenic Ghost‑Cell Tumor: An Uncommon Entity

Dentinojenik Hayalet Hücre Tümör: Yaygın Olmayan Entite

Görkem Tekin(OSMANGAZI UNIVERSITY)0000-0002-6572-2675
Nesrin Saruhan(ESKISEHIR OSMANGAZI UNIVERSITY)0000-0003-1160-4179
Ömür Dereci(ESKISEHIR OSMANGAZI UNIVERSITY)0000-0002-7867-7199
Yasin Koşar(ESKISEHIR OSMANGAZI UNIVERSITY)0000-0002-7673-0347
Melek Gürbüz(ESKISEHIR OSMANGAZI UNIVERSITY)0000-0001-7446-9547
Fuat Açıkalın(ESKISEHIR OSMANGAZI UNIVERSITY)0000-0003-1708-467X
Pages
211–216
Publication Date
2024-08-16
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therefore, histopathological differential diagnosis must be made.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Introduction: Dentinogenic Ghost Cell Tumor (DGCT) constitutes less than 3% of all odontogenic tumors, making it a rare entity characterized by local invasion.
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Key Findings & Data:Case Report: A 60-year-old male patient was referred to the oral and maxillofacial surgery clinic with a complaint of a painless swelling extending from the left upper molar region to the canine region.
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Conclusion & Impact:Therefore, histopathological differential diagnosis must be made.
🔬Design:Olgu Sunumu
📍Scope:Comprehensive Sample
⚙️Variables:Hayalet Hücre · Maksilla · Oral kavite

Abstract

Introduction: Dentinogenic Ghost Cell Tumor (DGCT) constitutes less than 3% of all odontogenic tumors, making it a rare entity characterized by local invasion. The histopathological features of DGCT are the presence of ghost cell layers and formation of dentinoid material with an ameloblastoma-like odontogenic epithelial proliferation. The peripheral variant of DGCT behaves less aggressively than the intraosseous variant and usually occurs on the anterior region of both jaws. Case Report: A 60-year-old male patient was referred to the oral and maxillofacial surgery clinic with a complaint of a painless swelling extending from the left upper molar region to the canine region. In the radiographic examination, destruction was observed in the maxillary bone where the lesion was located. Incisional biopsy revealed the diagnosis of DGCT. The patient was scheduled for surgery, but the lesion could not be excised because he refused the treatment. Conclusion: DGCT may present as a malignant-like lesion in the maxillary posterior region. Therefore, histopathological differential diagnosis must be made.

Özet

Amaç: Dentinojenik hayalet hücreli tümör (DHHT), tüm odontojenik tümörlerin %3'ünden azını oluşturur ve bu da onu lokal invazyonla karakterize nadir bir antite haline getirmektedir. DHHT'nin histopatolojik özellikleri, hayalet hücre tabakalarının varlığı ve dentinoid materyalin oluşumu ile ameloblastoma benzeri odontojenik epitelyal proliferasyonudur. DHHT'nin periferik varyantı, intraosseöz varyantına göre daha az agresif davranır ve genellikle her iki çenenin ön bölgesinde görülmektedir. Olgu Sunumu: 60 yaşındaki erkek hasta, sol üst çene molar bölgesinden kanin bölgesine kadar uzanan ağrısız şişlik şikayeti ile ağız, diş ve cerrahisi kliniğine yönlendirildi. Radyografik incelemede, lezyonun bulunduğu üst çene kemiğinde rezorpsiyon gözlendi. İnsizyonel biyopsi sonucunda DHHT tanısı konuldu. Hasta ameliyat için planlandı ancak tedaviyi reddettiği için lezyon çıkarılamadı. Sonuç: DHHT, maksiller posterior bölgede malign benzeri bir lezyon olarak ortaya çıkabilir. Bu nedenle mutlaka histopatolojik ayırıcı tanı yapılmalıdır.

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Cite This Article

Tekin, G., Saruhan, N., Dereci, Ö., Koşar, Y., Gürbüz, M., Açıkalın, F. (2024). Dentinogenic Ghost‑Cell Tumor: An Uncommon Entity. Aydın Dental Journal, Cilt: 10 Sayı: 2, 211–216. https://ajindex.com/articles/1458422

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