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Journals / BEYOGLU EYE JOURNAL / 2018 / Cilt: 3 - Sayı: 3

Multifocal Electroretinography in Diabetic Patients without Retinopathy

Özgür BALTA
Gülten SUNGUR
Mehmet YAKIN
Nurten ÜNLÜ
Oyku BEZEN BALTA
Eyüp ÖZCAN
Firdevs ÖRNEK
Pages
109–115
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It was found that there were negative correlation trends between diabetes duration and mfERG N1-P1 amplitude, there were negative, positive correlation trends between diabetes duration and N1 implicit times and P1 implicit times in all rings.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: This study aimed to assess the multifocal electroretinography (mfERG) findings in diabetic patients without retinopathy according to the HbA1c levels and diabetes duration.
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Key Findings & Data:Methods: A total of 62 eligible patients with Type 2 diabetes mellitus and 30 healthy controls which were matched by age and sex were included in the study.
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Conclusion & Impact:It was found that there were negative correlation trends between diabetes duration and mfERG N1-P1 amplitude, there were negative, positive correlation trends between diabetes duration and N1 implicit times and P1 implicit times in all rings.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Objectives: This study aimed to assess the multifocal electroretinography (mfERG) findings in diabetic patients without retinopathy according to the HbA1c levels and diabetes duration. Methods: A total of 62 eligible patients with Type 2 diabetes mellitus and 30 healthy controls which were matched by age and sex were included in the study. Only the right eye of each patient was analyzed. All of the participants underwent a comprehensive ophthalmic examination, and the mfERG responses which were N1-P1 amplitude, N1 implicit times and P1 implicit times were calculated. Results: The mfERG N1-P1 amplitude was significantly reduced in diabetic patients compared to controls in inner two rings. There was significant different between controls and stable patients’ mfERG P1 implicit times in ring 2. It was found that there were negative correlation trends between diabetes duration and mfERG N1-P1 amplitude, there were negative, positive correlation trends between diabetes duration and N1 implicit times and P1 implicit times in all rings. There was a statistically significant negative correlation between diabetes duration and N1-P1 amplitude only in ring 5. Furthermore, it was found that there were statistically significant positive correlations between diabetes duration and N1 implicit times in ring 1, 2 and 5. There was a significant correlation between diabetes duration and P1 implicit times only in ring 2. Conclusion: We demonstrated that mfERG N1-P1 amplitude was reduced in inner retinal areas (ring 1 and ring 2), and P1 implicit time was delayed only in ring 2 in Turkish diabetic patients without retinopathy. There was a statistically signif-icant correlation between diabetes duration and N1-P1 amplitude and N1 implicit times in some retinal areas.

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Cite This Article

BALTA, Ö., SUNGUR, G., YAKIN, M., ÜNLÜ, N., BALTA, O. B., ÖZCAN, E., ÖRNEK, F. (2018). Multifocal Electroretinography in Diabetic Patients without Retinopathy. BEYOGLU EYE JOURNAL, Cilt: 3 - Sayı: 3, 109–115. https://ajindex.com/articles/145789

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