Journals / BEYOGLU EYE JOURNAL / 2020 / Cilt: 5 - Sayı: 2

Evaluation of Clinical Findings, Optical Coherence Tomography, Fundus Fluorescein Angiography, and Indocyanine Green Angiography Imaging in Patients with Polypoidal Choroidal Vasculopathy

Pages
135–141
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

SD-OCT showed specific findings for PCV, but ICGA was the most useful test for diagnosis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: The aim of this study was to describe clinical findings as well as spectral-domain optical coherence tomography (SD-OCT), fundus fluorescein angiography (FA), and indocyanine green angiography (ICGA) findings of polypoidal choroidal vasculopathy (PCV).
📊
Key Findings & Data:Methods: This retrospective, observational case series included 144 eyes of 103 patients who were diagnosed with PCV between January 2014 and August 2016.
💡
Conclusion & Impact:SD-OCT showed specific findings for PCV, but ICGA was the most useful test for diagnosis.
🔬Design:Research Article
📍Scope:2014 Verileri
⚙️Variables:Domain Parameters

Özet

Objectives: The aim of this study was to describe clinical findings as well as spectral-domain optical coherence tomography (SD-OCT), fundus fluorescein angiography (FA), and indocyanine green angiography (ICGA) findings of polypoidal choroidal vasculopathy (PCV). Methods: This retrospective, observational case series included 144 eyes of 103 patients who were diagnosed with PCV between January 2014 and August 2016. Best corrected visual acuity, 90-diopter lens slit-lamp fundus biomicroscopy examination findings, color fundus photography, SD-OCT, FA, and ICGA findings were evaluated at the time of diagnosis. Results: Sixty-six patients (93 eyes, 64.1%) were male and 37 (51 eyes, 35.9%) were female. Sixty-two (60.2%) patients had unilateral involvement. The most common SD-OCT finding was retinal pigment epithelial detachment (PED). Red-orange subretinal lesions were seen in 20 eyes (13.9%). There was a single polyp in 21 (14.6%) eyes, and more than 1 polyp in 123 (85.4%) eyes observed with ICGA imaging. The polyps were located in the peripapillary area in 10 (6.9%) eyes, the macular area in 91 (63.2%) eyes, and the extramacular area in 1 (0.7%) eye. A significant branching vascular network was seen in the ICGA images of 112 (77.8%) eyes. Conclusion: In this study, the majority of patients were male, with unilateral macular polyps. A serous PED and an exudative pattern were the most common clinical manifestations. SD-OCT showed specific findings for PCV, but ICGA was the most useful test for diagnosis.

🔖

Cite This Article

GARİP, R., YASA, D., OZKAYA, A. (2020). Evaluation of Clinical Findings, Optical Coherence Tomography, Fundus Fluorescein Angiography, and Indocyanine Green Angiography Imaging in Patients with Polypoidal Choroidal Vasculopathy. BEYOGLU EYE JOURNAL, Cilt: 5 - Sayı: 2, 135–141. https://ajindex.com/articles/142630

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Gomi F, Tano Y. Polypoidal choroidal vasculopathy and treatments. Curr Opin Ophthalmol 2008;19:208–12
  2. Cackett P, Wong D, Yeo I. A classification system for polypoidal choroidal vasculopathy. Retina 2009;29:187–91
  3. Yang J, Yuan M, Wang E, Xia S, Chen Y. Noninvasive multimodal imaging in diagnosing polypoidal choroidal vasculopathy. BMC Ophthalmology 2019;19:229
  4. Alshahrani ST, Al Shamsi HN, ES Kahtani, NG Ghazi. Spectraldomain optical coherence tomography findings in polypoidal choroidal vasculopathy suggest a type 1 neovascular growth pattern. Clinical Ophthalmology 2014;8:1689–95
  5. Yannuzzi LA, Ciardella A, Spaide RF, Rabb M, Freund KB, Orlock DA. The expanding clinical spectrum of idiopathic polypoidal choroidal vasculopathy. Arch Ophthalmol 1997;115:478–85
  6. Yuzawa M, Mori R, Kawamura A. The origins of polypoidal choroidal vasculopathy. Br J Ophthalmol 2005;89:602–7
  7. Tan CS, Ngo WK, Lim LW, Tan NW, Lim TH. EVEREST study report 4: Fluorescein angiography features predictive of polypoidal choroidal vasculopathy. Clin Experiment Ophthalmol 2019;47:614–20
  8. Wen F, Chen C, Wu D, Li H. Polypoidal choroidal vasculopathy in elderly Chinese patients. Graefe’s Arch Clin Exp Ophthalmol 2004;242:625–9
  9. Anantharaman G, Ramkumar G, Gopalakrishnan M, Rajput A. Clinical features, management and visual outcome of polypoidal choroidal vasculopathy in Indian patients. Indian J Ophthalmol 2010;58:399–405
  10. Honda S, Matsumiya W, Negi A. Polypoidal choroidal vasculopathy: Clinical features and genetic predisposition. Ophthalmologica 2014;231:59–74
  11. Tan CS, Ngo WK, Chen JP, Tan NW, Lim TH. EVEREST study report 2: Imaging and grading protocol, and baseline characteristics of a randomised controlled trial of polypoidal choroidal vasculopathy. Br J Ophthalmol 2015;99:624–8
  12. Scassellati-Sforzolini B, Mariotti C, Bryan R, Yanuzzi LA, Giuliani M, Giovannini A. Polypoidal choroidal vasculopathy in Italy. Retina 2001;21:121–5
  13. Davis SJ, Lauer AK, Flaxel CJ. Polypoidal choroidal vasculopathy in white patients. Retina 2014;34:2185–91
  14. Byeon SH, Lee SC, Oh HS, Kim SS, Koh HJ, Kwon OW. Incidence and clinical patterns of polypoidal choroidal vasculopathy in Korean patients. Jpn J Ophthalmol 2008;52:57–62
  15. Koh AHC, Chen LJ, Chen SJ, Chen Y, Giridhar A, Iida T, et al. Polypoidal choroidal vasculopathy evidence-based guidelines for clinical diagnosis and treatment. Retina 2013;33:686–716
  16. Hou J, Tao Y, Li XX, Zhao MW. Clinical characteristi