Journals / Acta Medica / 2019 / Cilt: 50 - Sayı: 2

Gender Differences: Does It Affect Clinical, Radiological and Microbiological Features in Adult Non-Cystic Fibrosis Bronchiectasis?

Pages
25–31
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was no difference between gender and age, dyspnea, heam-optysis, BSI category, radiologic severity us ing Reiff’s score, microbiological features and bilevel positive airway pressure usage.Conclusion: We concluded that gender differences in non-CFBR might be clinically important in our study population.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: This study aimed to investigate the gender effect on the clin-ic, radiological, and microbiological features in adult non-cystic fibrosis bronchiectasis.Material and Methods: This was a cross-sectional study of 217 patients with adult non-CF BR.
📊
Key Findings & Data:Results: The mean age of patients was 49.7±15.3 years (range 18-82).
💡
Conclusion & Impact:There was no difference between gender and age, dyspnea, heam-optysis, BSI category, radiologic severity us ing Reiff’s score, microbiological features and bilevel positive airway pressure usage.Conclusion: We concluded that gender differences in non-CFBR might be clinically important in our study population.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Objective: This study aimed to investigate the gender effect on the clin-ic, radiological, and microbiological features in adult non-cystic fibrosis bronchiectasis.Material and Methods: This was a cross-sectional study of 217 patients with adult non-CF BR. Patients with a confirmed diagnosis of bronchiectasis with high resolution computed tomography were investigated. Patients were clin-ically stable in the previous four weeks enrolled in the study. Symptoms, pul-monary function tests, radiological findings, microbiological results, and bronchiectasis severity index (BSI) were recorded. Results: The mean age of patients was 49.7±15.3 years (range 18-82). Fourty-one percent patients had smoking history. BR patients had a history of pneumonia sequel (47.9%), post-tuberculosis (33.6%) and idiopathic (15.7%). Patients divided into gender groups: females in group I, n=122 (56.2%)) and males in group II, n=95 (43.8%). There were differences in cough (84.4% vs 71.6%, p=0.029), smoking history (19.7% vs 75.9 %,p=0.001), chronic obstruc-tive pulmonary disease (4.1% vs 37. 9%, p=0.001), diabetes mellitus (21.3% vs 9.5%, p=0.025), depression history (36.1% vs 10.6%, p=0.001), panic disorders (10.7% vs 3.2%, p=0.039), long term oxygen usage (6.6% vs 17.9%,p=0.017). Forty-two percent of male BR patients had post-tuberculosis history, fifty-six female had post-pneumonia history, also. FEV1 and FVC value were high-er in man (1.5±0.7 vs 1.9±0.9,p= 0.001; 1.9±0.7 vs 2.7±1.0, p=0.0001 respec-tively). And also, FEV1/FVC ratio was lower in male (73.8±12.3 vs 67.8±15.3, p=0.01). There was no difference between gender and age, dyspnea, heam-optysis, BSI category, radiologic severity us ing Reiff’s score, microbiological features and bilevel positive airway pressure usage.Conclusion: We concluded that gender differences in non-CFBR might be clinically important in our study population. It is important to consider the gender differencesmight be effect symptoms, comorbidity, and pulmonary function test results in non-CF BR patients.

🔖

Cite This Article

NİKSARLIOĞLU, E. Y. (2019). Gender Differences: Does It Affect Clinical, Radiological and Microbiological Features in Adult Non-Cystic Fibrosis Bronchiectasis?. Acta Medica, Cilt: 50 - Sayı: 2, 25–31. https://ajindex.com/articles/141985

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (12)

  1. Pignataro FS, Bonini M, Forgione A, et al. Asthma and gen-der: The female lung. Pharmacological Research 2017; 119: 384-90.
  2. Sakurai H, Samura H, Goya T, et al. Survival differences by gender for resected non-small cell lung cancer A ret-rospective analysis of 12 509 cases in a Japanese Lung Cancer Registry Study. J Thorac Oncol 2010; 5: 1594-601.
  3. Rosenfeld M, Davis R, FitzSimmons S, et al. Gender gap in cystic fibrosis mortality. Am J Epidemiol 1997; 145: 794-803. Mclntye K. Gender and survival in cystic fibrosis. Curr Opin Pulm Med 2013; 19: 692-97.
  4. Pasteur MC, Bilton D, Hill AT. British Thoracic Society guideline for non-CF bronchiectasis. Thorax 2010; 65: Suppl. 1, i1-i58. White AJ, Gompertz S, Bayley DL, et al. Resolution of bron-chial inflammation is related to bacterial eradication fol-lowing treatment of exacerbations of chronic bronchitis. Thorax 2003; 58(8): 680-85.
  5. Reiff DB, Wells AU, Carr DH, et al. CT findings in bronchiec-tasis: limited value in distinguishing between idiopathic and specific types. AJR Am J Roentgenol 1995; 165: 261-67.
  6. Chalmers JD, Goeminne P, Aliberti S, et al. The bronchiec-tasis severity index. Am J Respir Crit Care Med 2014; 189(5): 576-85.
  7. Weycker D, Hansen GL, Seifer FD. Prevalence and inci-dence of noncystic fibrosis bronchiectasis among US adults in 2013. Chronic Respir Dis 2017; 14: 377-84.
  8. Polverino E, Goeminne PC, McDonnell MJ, et al. European Respiratory Society guidelines for the management of adult bronchiectasis. Eur Respir J 2017; 50: 1700629. Byun MK, Chang J, Kim HJ, et al. Differences of the lung mi-crobiome in patients with clinically stable and exacerbat-ed bronchiectasis. PLoS One 2017; 12(8): e0183553. Leynaert B, Bousquet J, Hemry C, et al. Is bronchial hyper-responsiveness more frequent in women than in men? A population-based study. Am J Respir Crit Care Med 1997; 156: 1413-20.
  9. Lanqdeau JB, Day A, Turcotte H, et al. Gender d’fferenc-es in the prevalence of airway hyperresponsiveness and asthma in athletes. Respir Med 2009; 103: 401-06.
  10. Kavalcikova-Bogdanova N, Buday T, Plevkova J, et al. Chronic cough as a female gender issue. Advs Exp Med Biol. 2016; 905: 69-78.
  11. Morice AH, Jakes AD, Faruqi S, et al. A worldwide survey of chronic cough: a manifestation of enhanced somatosen-sory response. Eur Respir J. 2014; 44: 1149-55.
  12. Campainha S, Ribeiro C, Guimarae M, et al. Case report vocal cord dysfunction: a frequently forgotten entitiy. Case Rep Pulmonol. 2012; 2012: 525493. HarmsCA. Does gender affect pulm