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Journals / International Journal of Secondary Metabolite / 2024 / Volume: 11 Issue: 4

Comparison of high antioxidant ZnONPs produced from different fungi as alternative biomaterials

Olcay Gençyılmaz(Çankırı Karatekin Üniversitesi)0000-0002-7410-2937
Mohanad Fawzi Mutar Mutar(CANKIRI KARATEKIN UNIVERSITY)0009-0008-1285-8342
Pages
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Publication Date
2024-11-03
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Based on these results, the biosynthesis of ZnO nanoparticles (ZnONPs) using Penicillium citrinum, Fusarium solani, Aspergillus flavus and Aspergillus niger fungal species is proposed for the production of ZnONPs as a biomaterial with remarkable antibacterial properties and various morphologies.

📌 3 Key Takeaways

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Objective & Hypothesis:In this study, zinc oxide nanoparticles (ZnONPs), a promising alternative biomaterial, were synthesized using a non-toxic, cost-effective green synthesis approach using various fungal species (Penicillium citrinum, Fusarium solani, Aspergillus flavus and Aspergillus niger).
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Key Findings & Data:ZnO nanoparticles (ZnONPs) crystallized in a hexagonal wurtzite structure with grain sizes ranging from 45 to 61 nm.
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Conclusion & Impact:Based on these results, the biosynthesis of ZnO nanoparticles (ZnONPs) using Penicillium citrinum, Fusarium solani, Aspergillus flavus and Aspergillus niger fungal species is proposed for the production of ZnONPs as a biomaterial with remarkable antibacterial properties and various morphologies.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:ZnONPs · Green synthesis · Fungi

Abstract

In this study, zinc oxide nanoparticles (ZnONPs), a promising alternative biomaterial, were synthesized using a non-toxic, cost-effective green synthesis approach using various fungal species (Penicillium citrinum, Fusarium solani, Aspergillus flavus and Aspergillus niger). The effect of different fungal species on the structural, optical, morphological and antimicrobial properties of ZnO nanoparticles (ZnONPs) was compared. ZnO nanoparticles (ZnONPs) crystallized in a hexagonal wurtzite structure with grain sizes ranging from 45 to 61 nm. Fungal species had a significant effect on the surface plasmon resonance (SPR) peak observed at 302 nm. ZnONPs were obtained in different morphologies such as nanodiscs, nanospheres, nanorchins and nanonuts, and it was determined that fungal species had a significant effect on these structures. The antibacterial activity of ZnONPs against Candida albicans, Streptococcus mutans, Pseudomonas aeruginosa, Eosinophilic pneumonia and Staphylococcus aureus was investigated. The effect of these nanoparticle shapes on antibacterial activity was evaluated. ZnONPs were found to have a significant antimicrobial effect especially on Candida albicans and Streptococcus mutans. ZnONPs produced only with Aspergillus niger fungus were found to have a strong antimicrobial effect especially on Staphylococcus aureus. Based on these results, the biosynthesis of ZnO nanoparticles (ZnONPs) using Penicillium citrinum, Fusarium solani, Aspergillus flavus and Aspergillus niger fungal species is proposed for the production of ZnONPs as a biomaterial with remarkable antibacterial properties and various morphologies.

Özet

In this study, zinc oxide nanoparticles (ZnONPs), a promising alternative biomaterial, were synthesized using a non-toxic, cost-effective green synthesis approach using various fungal species (Penicillium citrinum, Fusarium solani, Aspergillus flavus and Aspergillus niger). The effect of different fungal species on the structural, optical, morphological and antimicrobial properties of ZnO nanoparticles (ZnONPs) was compared. ZnO nanoparticles (ZnONPs) crystallized in a hexagonal wurtzite structure with grain sizes ranging from 45 to 61 nm. Fungal species had a significant effect on the surface plasmon resonance (SPR) peak observed at 302 nm. ZnONPs were obtained in different morphologies such as nanodiscs, nanospheres, nanorchins and nanonuts, and it was determined that fungal species had a significant effect on these structures. The antibacterial activity of ZnONPs against Candida albicans, Streptococcus mutans, Pseudomonas aeruginosa, Eosinophilic pneumonia and Staphylococcus aureus was investigated. The effect of these nanoparticle shapes on antibacterial activity was evaluated. ZnONPs were found to have a significant antimicrobial effect especially on Candida albicans and Streptococcus mutans. ZnONPs produced only with Aspergillus niger fungus were found to have a strong antimicrobial effect especially on Staphylococcus aureus. Based on these results, the biosynthesis of ZnO nanoparticles (ZnONPs) using Penicillium citrinum, Fusarium solani, Aspergillus flavus and Aspergillus niger fungal species is proposed for the production of ZnONPs as a biomaterial with remarkable antibacterial properties and various morphologies.

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Cite This Article

Gençyılmaz, O., Mutar, M. F. M. (2024). Comparison of high antioxidant ZnONPs produced from different fungi as alternative biomaterials. International Journal of Secondary Metabolite, Volume: 11 Issue: 4. https://doi.org/10.21448/ijsm.1485796

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References (47)

  1. Abdelhakim, H.K., El-Sayed, E.R., & Rashidi, F.B. (2020). Biosynthesis of zinc oxide nanoparticles withantimicrobial, anticancer, antioxidant and photocatalytic activities by theendophytic Alternaria tenuissima. Journal of Applied Microbiology, 128, 1634–1646. https://doi.org/10.1111/jam.14581
  2. Ahmad, H., Venugopal, K., Rajagopal, K., De Britto, S., Nandini, B., Pushpalatha, H.G., & Jogaiah, S. (2020). Green synthesis and characterization of zinc oxide nanoparticles using Eucalyptus globules and their fungicidal ability against pathogenic fungi of apple orchards. Biomolecules, 10(3), 425. https://doi.org/10.3390/biom10030425
  3. Alavi, M., & Nokhodchi, A. (2021). Synthesis and modification of bio-derived antibacterial Ag and ZnO nanoparticles by plants, fungi, and bacteria. Drug Discovery Today, 26(8), 1953-1962. https://doi.org/10.1016/j.drudis.2021.03.030
  4. Bhardwaj, N., Gaur, A., & Yadav, K. (2017). Effect of doping on optical properties in BiMn1−x (TE)xO3 (where x= 0.0, 0.1 and TE= Cr, Fe, Co, Zn) nanoparticles synthesized by microwave and sol gel methods. Applied Physics A, 123(6), 429 436. https://doi.org/10.1007/s00339-017-1042-y
  5. Bhuyan, T., Mishra, K., Khanuja, M., Prasad, R., & Varma, A. (2015). Biosynthesis of zinc oxide nanoparticles from Azadirachta indica for antibacterial and photocatalytic applications. Materials Science in Semiconductor Processing, 32, 55 61. https://doi.org/10.1016/j.mssp.2014.12.053
  6. Brady, N.G., O’Leary, S.L., Moormann, G.C., Singh, M. K., Watt, J., & Bachand, G.D. (2023). Mycosynthesis of Zinc Oxide Nanoparticles Exhibits Fungal Species Dependent Morphological Preference. Nano Micro Small, 19(15), 2205799. https://doi.org/10.1002/smll.202205799
  7. Chauhan, R., Reddy, A., & Abraham, J., (2015). Biosynthesis of silver and zinc oxide nanoparticles using Pichia fermentans JA2 and their antimicrobial property. Applied Nanoscience, 5, 63–71. https://doi.org/10.1007/s13204-014-0292-7
  8. Chaurasia, V., Chand N., & Bajpai, S.K. (2010). Water Sorption Properties and Antimicrobial Action of Zinc Oxide Nanoparticles-Loaded Cellulose Acetate Films. Journal of Macromolecular Sciencer Part A: Pure and Applied Chemistry, 47, 1 9. https://doi.org/10.1080/10601320903539207
  9. Cooper, K.E. (1955). Theory of Antibiotic Inhibition Zones in Agar Media. Nature 176, 510–511. https://doi.org/10.1038/176510b0
  10. Dhillon, G.S., Brar, S.K., Kaur, S., & Verma, M. (2012). Green approach for nanoparticle biosynthesis by fungi. Critical Reviews in Biotechnology, 32(1), 49 73. https://doi.org/10.3109/07388551.2010.550568
  11. Guilger-Casagrande, M., & de Lima, R. (2019). Synthesis of Silver Nanoparticles Mediated by Fungi: A Review. Frontiers in Bioengineering and Biotechnology, 7(287), 1-16. https://doi.org/10.3389/fbioe.2019.00287
  12. Gupta, S., Ravi, R.K., & Pathak, B. (2024). Photocatalytic Removal of Anthracene Using Zinc Oxide Nanoparticles Synthesized by Fusarium proliferatumWC416. Geomicrobiology Journal, 41(1), 72-81, 10. https://doi.org/1080/01490451.2023.2272621
  13. Günay, K., Leblebici, Z., & Koca, F.D. (2021). Biosynthesis, characterization and anti-bacterial effect of zinc nanoparticles (ZnO NP). Nevşehir Journal of Science and Technology, 10(1), 56-66. https://doi.org/10.17100/nevbiltek.917256
  14. Jain, N., Bhargava, A., Tarafdar, J.C., Singh, S.K., & Panwar, J. (2013). A biomimetic approach towards synthesis of zinc oxide nanoparticles. Applied Microbiology Biotechnology, 97, 859–869. https://doi.org/10.1007/s00253-012-3934-2
  15. Jain, N., Bhargava, A., & Panwar, J., (2014). Enhanced photocatalytic degradation of methylene blue using biologically synthesized “protein-capped” ZnO nanoparticles. Chemical Engineering Science, 243, 549–555. https://doi.org/10.1016/j.cej.2013.11.085
  16. Kalpana, V.N., Kataru, B.A.S., Sravani, N., Vigneshwari, T., Panneerselvam. A., & Rajeswari, V.D. (2018) Biosynthesis of zinc oxide nanoparticles using culture filtrates of Aspergillus niger: Antimicrobial textiles and dye degradation studies. Opennano, 3, 48-55. https://doi.org/10.1016/j.onano.2018.06.001
  17. Kalpana, V.N., Kataru, B.A.S., Sravani, N., Vigneshwari, T., Panneerselvam, A., & Rajeswari, V.D. (2022). Annona reticulata leaves-assisted synthesis of zinc oxide nanoparticles and assessment of cytotoxicity and photocatalytic impact. Materials Letters, 309, 131379. https://doi.org/10.1016/j.matlet.2021.131379
  18. Kumar, R.V., Vinoth, S., Baskar, V., Arun, M., & Gurusaravanan, P. (2022). Synthesis of zinc oxide nanoparticles mediated by Dictyota dichotoma endophytic fungi and its photocatalytic degradation of fast green dye and antibacterial applications. South African Journal of Botany, 15, 337-344. https://doi.org/10.1016/j.sajb.2022.03.016
  19. L. Nehru, G. D. Kandasamy, V. Sekar, M. Ali Alshehri, C. Panneerselvam, A. Alasmari, & P. Kathirvel, (2023). Green synthesis of ZnO-NPs using endophytic fungal extract of Xylaria arbuscula from Blumea axillaris and its biological applications. Artificial Cells, Nanomedicine, and Biotechnology, 51(1), 318 333. https://doi.org/10.1080/21691401.2023.2232654
  20. Mahamuni Badiger, P., Ghare, V., Nikam, C., & Patil, N. (2023). The fungal infections and their inhibition by Zinc oxide nanoparticles: an alternative approach to encounter drug resistance. Nucleus, 1-19. https://doi.org/10.1007/s13237-023-00439-1
  21. Malaikozhundan, B., Vaseeharan, B., Vijayakumar, S., Pandiselvi, K., Kalanjiam, M.A.R., Murugan, K., & Benelli, G. (2017). Biological therapeutics of Pongamia pinnata coated zinc oxide nanoparticles against clinically important pathogenic bacteria, fungi and MCF-7 breast cancer cells. Microbial Pathogenesis, 104, 268 277. https://doi.org/10.1016/j.micpath.2017.01.029
  22. Meruvu, H., Vangalapati, M., Chippada, S.C., & Bammidi, S.R. (2011). Synthesis and characterization of zinc oxide nanoparticles and its antimicrobial activity against Bacillus subtilis and Escherichia coli. Rasayan Journal of Chemistry, 4(1), 217–222.
  23. Moghaddam, A.B, Namvar, F., Moniri, M., Tahir, P.M., Azizi, S., & Mohamad, R. (2015). Nanoparticles Biosynthesized by Fungi and Yeast: A Review of Their Preparation, Properties, and Medical Applications. Molecules, 20, 16540 16565. https://doi.org/10.3390/molecules200916540
  24. Moghaddam, A.B., Moniri, M., Azizi, S., Rahim, R.A., Ariff, A.B., Saad, W.Z., Namvar, F., Navaderi, M., & Mohamad, R. (2017). Biosynthesis of ZnO Nanoparticles by a New Pichia kudriavzevii Yeast Strain and Evaluation of Their Antimicrobial and Antioxidant Activities. Molecules, 22, 872. https://doi.org/10.3390/molecules22060872
  25. Mohamed, A.A., Fouda, A., Abdel-Rahman, M.A., Hassan, S.D., El-Gamal, Salem, M.S., & Shaheen, S.S. & (2019). Fungal strain impacts the shape, bioactivity and multifunctional properties of green synthesized zinc oxide nanoparticles, Biocatalysis and Agricultural Biotechnology, 19, 101103. https://doi.org/10.1016/j.bcab.2019.101103
  26. Molina, D.A., Giner‑Casares, J.J., & Cano, M. (2020). Bioconjugated Plasmonic Nanoparticles for Enhanced Skin Penetration. Topics in Current Chemistry, 378(8), 1 17. https://doi.org/10.1007/s41061-019-0273-0
  27. Moormann, G.C., & Bachand, G.D. (2021). Biosynthesis of Zinc Oxide Nanoparticles using Fungal Filtrates. Sand 2021, 9437R.
  28. Moormann, G.C., & Bachand, G.D. (2021). Biosynthesis of Zinc Oxide Nanoparticles using Fungal Filtrates. Center for Intergarted Nanotechnologies (CINT), 9437R, 1-4. https://doi.org/10.2172/1817833
  29. Pariona, N., Paraguay-Delgado, F., Basurto-Cereceda, S., Morales Mendoza, J.E., Hermida-Montero, L.A., & Mtz-Enriquez, A.I. (2020). Shap dependent antifungal activity of ZnO particles against phytopatogenic Fungi. Applied Nanoscience, 10, 435–43.
  30. Patterson, A.L. (1939). The Scherrer Formula for X-Ray Particle Size Determination. Physical Review Journals, 56, 978. https://doi.org/10.1103/PhysRev.56.978
  31. Pesika, N.S., Stebe, K.J., & Searson, P.C. (2003). Relationship between absorbance spectra and particle size distributions for quantum-sized nanocrystals. The Journal of Physical Chemistry B, 107(38), 10412–10415. https://doi.org/10.1021/jp0303218
  32. Qianwei, L.I., Feixue, L.I.U., Min, L.I., Chen, C., & Gadd, G.M. (2022). Nanoparticle and nanomineral production by fungi. Fungal Biology Reviews, 41, 31e44. https://doi.org/10.1016/j.fbr.2021.07.003
  33. Rajan, A., Cherian, E., & Baskar, G. (2016). Biosynthesis of zinc oxide nanoparticles using Aspergillus fumigatus JCF and its antibacterial activity. International Journal of Modern Science and Technology, 1(2), 52-57.
  34. Rajiv, P., Rajeshwari, S., & Venckatesh, R. (2013). Bio-Fabrication of zinc oxide nanoparticles using leaf extract of Parthenium hysterophorus L. and its size-dependent antifungal activity against plant fungal pathogens. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 112, 384–387
  35. Sarkar, J., Ghosh, M., Mukherjee, A., Chattopadhyay, D., & Acharya, K. (2014). Biosynthesis and safety evaluation of ZnO nanoparticles. Bioprocess and Biosystems Engineering, 37, 165–171. https://doi.org/10.1007/s00449-013-0982-7
  36. Senthilkumar, S.R., & Sivakumar T. (2014). Green tea (Camellia sinensis) mediated synthesis of zinc oxide (ZnO) nanoparticles and studies on their antimicrobial activities. Int. J. Pharm. Pharm. Sci., 6(6), 461–465.
  37. Singh, I., & Singh, S., (2019). Study of algal mediated biosynthesis of nanoparticle: future of green nanotechnology. Current Life Sciences, 5(1), 7 14. https://doi.org/10.5281/zenodo.2666643
  38. Soosen, S.M., Bose, L., & George, K.C. (2009). Optical properties of ZnO nanoparticles. Academic Review, 16(1-2), 57–65.
  39. Tauc, J., & Menth, A. (1972). States in the gap. Journal of Non-Crystal Solids, 569, 8–10. https://doi.org/10.1016/0022-3093(72)90194-9
  40. Urbach, F. (1953). The long-wavelength edge of photographic sensitivity and of the electronic absorption of solids. Physical Review, 92(5), 1324. https://doi.org/10.1103/PhysRev.92.1324
  41. Vlad, S., Tanase, C., Macocinschi, D., Ciobanu, C., Balaes, T., Filip, D., & Gradinaru, L.M. (2012). Antifungal behaviour of polyurethane membranes with zinc oxide nanoparticles. Journal of Nanomaterial Biostructructure, 7, 51–58.
  42. Venkatesh, K.S., Palani, N.S., Krishnamoorthi, S.R., Thirumal, V., & Ilangovan, R. (2013). Fungus mediated biosynthesis and characterization of zinc oxide nanorods. AIP Conference Proceeding, 1536, 93–94. https://doi.org/10.1063/1.4810116
  43. Vettumperumal, R., Kalyanaraman, S., Santoshkumar, B., & Thangavel, R. (2016). Estimation of electron–phonon coupling and Urbach energy in group-I elements doped ZnO nanoparticles and thin films by sol–gel method. Materials Research Bulletin, 77, 101–110. https://doi.org/10.1016/j.materresbull.2016.01.015
  44. Wang, L., Hu, C., & Shao, L., (2017). The antimicrobial activity of nanoparticles: present situation and prospects for the future. International Journal of Nanomedicine, 12, 1227–49. https://doi.org/10.2147/IJN.S121956
  45. Yavuz, İ., & Yılmaz, E.Ş. (2021), Nanoparticles with Biological Systems, Journal of Gazi University Science Faculty, 1, 93-108. https://doi.org/10.5281/zenodo.4843592
  46. Yoldas, B.E., & Partlow, D.P. (1985). Formation of broad band antireflective coatings on fused silica for high power laser applications. Thin Solid Films, 129(1–2), 1–14. https://doi.org/10.1016/0040-6090(85)90089-6
  47. Zeghoud, S., Hemmami, H., Seghir, B.B., Amor, I.B., Kouadri, I., Rebiai, A., Simal-Gandara, J. (2022). A review on biogenic green synthesis of ZnO nanoparticles by plant biomass and their applications. Materials Today Communications, 33, 104747. https://doi.org/10.1016/j.mtcomm.2022.104747