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Journals / International Journal of Secondary Metabolite / 2026 / Volume: 12 Issue: 1

Chemical compositions of essential oils, antimicrobial effect and antioxidant activity studies of Hyoscyamus niger L. from Türkiye

Şule İnci(FIRAT ÜNİVERSİTESİ)0000-0002-4022-5269
Pelin Yılmaz Sancar(FIRAT UNIVERSITY)0000-0002-6134-622X
Azize Demirpolat(BINGOL UNIVERSITY)0000-0001-7192-185X
Sevda Kırbağ(FIRAT UNIVERSITY)0000-0002-4337-8236
Şemsettin Civelek(FIRAT UNIVERSITY)0000-0003-1398-585X
Pages
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Publication Date
2025-02-20
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These findings highlight the potential antimicrobial and antioxidant applications of H. niger essential oils and methanol extracts.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:This study investigated the essential oil components of Hyoscyamus niger L. and their antimicrobial and antioxidant properties.
📊
Key Findings & Data:Essential oils were extracted separately from the aerial parts and seeds of the plant using the hydrodistillation method.
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Conclusion & Impact:These findings highlight the potential antimicrobial and antioxidant applications of H. niger essential oils and methanol extracts.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Antimicrobial and Antioxidant activity · Essential oil composition · Hyoscyamus niger L.

Abstract

This study investigated the essential oil components of Hyoscyamus niger L. and their antimicrobial and antioxidant properties. Essential oils were extracted separately from the aerial parts and seeds of the plant using the hydrodistillation method. Antimicrobial activity was evaluated using the disk diffusion method, while antioxidant activity was assessed by measuring the total antioxidant status (TAS), total oxidant status (TOS), and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging capacity. The primary essential oil components of the aerial parts were identified as phytol (52.09%) and hexahydrofarnesyl acetone (19.66%). Hydrodistillation of the seeds yielded 0.7% (v/w) yellow oils, comprising 41 components that accounted for 99.0% of the oil. The major components in the seed oils were hexahydrofarnesyl acetone (46.36%) and hexanal (9.05%). Methanol extracts of the aerial parts demonstrated inhibitory effects on pathogenic microorganisms, with inhibition zones ranging from 13±0.46 to 32±0.11 mm. The TAS and TOS values of the methanol extracts were calculated as 3.77±0.0 mmol and 6.94±0.0 μmol, respectively. The DPPH radical scavenging activity increased with rising extract concentrations. These findings highlight the potential antimicrobial and antioxidant applications of H. niger essential oils and methanol extracts.

Özet

This study investigated the essential oil components of Hyoscyamus niger L. and their antimicrobial and antioxidant properties. Essential oils were extracted separately from the aerial parts and seeds of the plant using the hydrodistillation method. Antimicrobial activity was evaluated using the disk diffusion method, while antioxidant activity was assessed by measuring the total antioxidant status (TAS), total oxidant status (TOS), and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging capacity. The primary essential oil components of the aerial parts were identified as phytol (52.09%) and hexahydrofarnesyl acetone (19.66%). Hydrodistillation of the seeds yielded 0.7% (v/w) yellow oils, comprising 41 components that accounted for 99.0% of the oil. The major components in the seed oils were hexahydrofarnesyl acetone (46.36%) and hexanal (9.05%). Methanol extracts of the aerial parts demonstrated inhibitory effects on pathogenic microorganisms, with inhibition zones ranging from 13±0.46 to 32±0.11 mm. The TAS and TOS values of the methanol extracts were calculated as 3.77±0.0 mmol and 6.94±0.0 μmol, respectively. The DPPH radical scavenging activity increased with rising extract concentrations. These findings highlight the potential antimicrobial and antioxidant applications of H. niger essential oils and methanol extracts.

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Cite This Article

İnci, Ş., Sancar, P. Y., Demirpolat, A., Kırbağ, S., Civelek, Ş. (2025). Chemical compositions of essential oils, antimicrobial effect and antioxidant activity studies of Hyoscyamus niger L. from Türkiye. International Journal of Secondary Metabolite, Volume: 12 Issue: 1. https://doi.org/10.21448/ijsm.1456885

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