Journals / Harran Üniversitesi Veteriner Fakültesi Dergisi / 2026 / Volume: 14 Issue: 1

Comparative anatomy of the pelvic cavity of rat strains in a translational aspect

Ratlarda pelvik boşluğun karşılaştırmalı anatomisi

Yasemin Üstündağ(DOKUZ EYLÜL ÜNİVERSİTESİ)0000-0002-8836-0371
Osman Yılmaz(Dokuz Eylül Üniversitesi Sağlık Bilimleri Enstitüsü)0000-0001-7817-7576
Pages
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Publication Date
2025-06-19
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, anatomically, Lewis is the most suitable laboratory rat strain that does not predispose to labor dystocia, followed by the Wistar Albino strain.

📌 3 Key Takeaways

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Objective & Hypothesis:The anatomy of the pelvic cavity has significant importance in daily clinical applications and surgical interventions such as determining dystocia, surgery of rectal cancers and mesorectal excision, treatment of twisted pouch syndrome and percutaneous sacroiliac screw fixation, and pelvic floor disorders.
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Key Findings & Data:According to the Kruskal-Wallis analysis to determine whether there is any difference between strains, significant differences were observed between the strains for the length of the symphysis, oblique diameter, true conjugate, anatomical conjugate, and diagonal conjugate parameters (p<0.05).
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Conclusion & Impact:In conclusion, anatomically, Lewis is the most suitable laboratory rat strain that does not predispose to labor dystocia, followed by the Wistar Albino strain.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Diameter · Dystocia · Pelvic inlet

Abstract

The anatomy of the pelvic cavity has significant importance in daily clinical applications and surgical interventions such as determining dystocia, surgery of rectal cancers and mesorectal excision, treatment of twisted pouch syndrome and percutaneous sacroiliac screw fixation, and pelvic floor disorders. This study aims to determine the diameters and area calculations of the pelvic cavity in mostly preferred rat strains (Wistar Albino, Brown Norway, Sprague Dawley, and Lewis) and investigate the suitability of rats in translational studies in which anatomical conditions are not a cause of dystocia. In this study, pelvis bones were used. Each group consisted of six rats. They were examined morphologically and morphometrically. According to the Kruskal-Wallis analysis to determine whether there is any difference between strains, significant differences were observed between the strains for the length of the symphysis, oblique diameter, true conjugate, anatomical conjugate, and diagonal conjugate parameters (p<0.05). In conclusion, anatomically, Lewis is the most suitable laboratory rat strain that does not predispose to labor dystocia, followed by the Wistar Albino strain. These two strains may be a choice for studies on physiological dystocia. On the other hand, Sprague Dawley is less suitable for experimental studies involving the pelvic inlet, particularly those related to labor dystocia caused by anatomical factors.

Özet

Pelvik boşluğun anatomisi, klinik uygulamalar ve rektal kanserlerin cerrahisi, mezorektal eksizyon, torsiyonlu kese sendromu tedavisi, perkütan sakroiliak vida tespiti ve pelvik taban bozuklukları gibi cerrahi müdahalelerde önemli bir yere sahiptir. Bu çalışma, en çok tercih edilen sıçan türlerinde (Wistar Albino, Brown Norway, Sprague Dawley ve Lewis) pelvik boşluğunun çaplarını ve alan hesaplamalarını belirlemeyi ve anatomik koşulların güç doğuma neden olmadığı translasyonel çalışmalarda sıçanların uygunluğunu araştırmayı amaçlamaktadır. Çalışmada pelvis kemikleri kullanılmıştır. Her grup altı sıçandan oluşmuştur. Kemikler morfolojik ve morfometrik olarak incelenmiştir. Türler arasında fark olup olmadığını belirlemek için yapılan Kruskal-Wallis analizi sonuçlarına göre LS, DO, CV, CA ve CD parametrelerinde türler arasında anlamlı farklar gözlenmiştir (p<0.05). Sonuç olarak, anatomik açıdan Lewis, güç doğuma eğilim göstermeyen en uygun laboratuvar sıçan türü olup, bunu Wistar Albino türü izlemektedir. Bu iki tür, fizyolojik güç doğum ile ilgili çalışmalarda tercih edilebilir. Öte yandan, Sprague Dawley, özellikle anatomik faktörlere bağlı güç doğum ile ilgili pelvik giriş çalışmalarında daha az uygun bir türdür.

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Cite This Article

Üstündağ, Y., Yılmaz, O. (2025). Comparative anatomy of the pelvic cavity of rat strains in a translational aspect. Harran Üniversitesi Veteriner Fakültesi Dergisi, Volume: 14 Issue: 1. https://doi.org/10.31196/huvfd.1621777

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