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Journals / Kocatepe Veteriner Dergisi / 2025 / Cilt: 18 Sayı: 4

Functional Anatomy of the Carpal Region in Sprague Dawley Strain Rats

Sprague Dawley Soyu Ratlarda Carpal Bölgenin Fonksiyonel Anatomisi

Yasemin Üstündağ(DOKUZ EYLÜL ÜNİVERSİTESİ)0000-0002-8836-0371
Ümit Koçak(DOKUZ EYLÜL ÜNİVERSİTESİ)0009-0008-1281-8623
Belkin Giousemoglou(DOKUZ EYLÜL ÜNİVERSİTESİ)0009-0006-7314-1180
Muhammed Ali Aydemir(BURDUR MEHMET AKİF ERSOY ÜNİVERSİTESİ)0009-0005-4497-3650
Ahmet Berat Yakar(DOKUZ EYLÜL ÜNİVERSİTESİ)0009-0001-9336-6735
Pages
451–461
Publication Date
2025-12-24
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Compared to human and rat carpal bones and carpal tunnel, both of the structures are quite different each other.Therefore, it has been concluded that these rats are unsuitable for experimental surgical models, especially those focusing on the carpal region.

📌 3 Key Takeaways

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Objective & Hypothesis:Dating back to 1830, Rattus norvegicus holds the distinction of being one of the first mammals domesticated for use in scientific researches.
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Key Findings & Data:Additionally, the study seeks to elucidate how the carpal tunnel, which is important in translational anatomy, is formed and which structures pass through it.In the study, seven 9-month-old female Sprague Dawley strain rats carpal regions were examined, macroscobically, morphometrically and radiologically.The carpal bones of Sprague Dawley rats were examined and found to be arranged in two rows: proximal and distal.
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Conclusion & Impact:Compared to human and rat carpal bones and carpal tunnel, both of the structures are quite different each other.Therefore, it has been concluded that these rats are unsuitable for experimental surgical models, especially those focusing on the carpal region.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Karpal kemikler · karpal tünel · sıçan

Abstract

Dating back to 1830, Rattus norvegicus holds the distinction of being one of the first mammals domesticated for use in scientific researches. While detailed anatomical information about the human carpal region is available, such information is lacking for rats. The current study aims to resolve the ambiguity in the literature by determining which bones constitute the carpal bones of Sprague Dawley starin rats ,the number and arrangement of these bones. Additionally, the study seeks to elucidate how the carpal tunnel, which is important in translational anatomy, is formed and which structures pass through it.In the study, seven 9-month-old female Sprague Dawley strain rats carpal regions were examined, macroscobically, morphometrically and radiologically.The carpal bones of Sprague Dawley rats were examined and found to be arranged in two rows: proximal and distal. A total of six carpal bones were identified, two in the proximal row and four in the distal row. The formation of the carpal tunnel in rats has been observed as follows. It is noted to form between the distal end of the antebrachium and the distal carpal bones. Compared to human and rat carpal bones and carpal tunnel, both of the structures are quite different each other.Therefore, it has been concluded that these rats are unsuitable for experimental surgical models, especially those focusing on the carpal region.

Özet

1830 yılına kadar uzanan geçmişiyle Rattus norvegicus, bilimsel araştırmalarda kullanılmak üzere evcilleştirilen ilk memelilerden biri olma özelliğini taşımaktadır. İnsan el bileği (karpal) bölgesine ait ayrıntılı anatomik bilgiler mevcutken, sıçanlar için bu tür bilgiler yetersizdir. Mevcut çalışma, literatürdeki belirsizlikleri gidermeyi amaçlayarak Sprague Dawley soyu sıçanların karpal kemiklerini, bu kemiklerin sayısını ve dizilimini belirlemeyi hedeflemektedir. Ayrıca, translasyonel anatomi açısından önemli olan karpal tünelin nasıl oluştuğunu ve hangi yapıların bu tünelden geçtiğini ortaya koymayı amaçlamaktadır. Çalışmada, 7 adet 9 aylık dişi Sprague Dawley soyu sıçanın karpal bölgesi makroskobik, morfometrik ve radyolojik yöntemlerle incelenmiştir. Sprague Dawley soyu sıçanların karpal kemiklerinin iki sıra halinde dizildiği gözlemlenmiştir: proksimal ve distal. Toplamda altı karpal kemik tespit edilmiş olup, bunların iki tanesi proksimal sırada, dört tanesi ise distal sırada yer almaktadır. Sıçanlarda karpal tünelin oluşumu şu şekilde gözlemlenmiştir: Antebrachium’un distal ucu ile distal karpal kemikler arasında bir tünel oluşmaktadır. İnsanlardaki ve sıçanlardaki karpal kemikler ve karpal tünel kıyaslandığında, bu yapıların birbirinden oldukça farklı olduğu belirlenmiştir. Bu nedenle, Sprague Dawley soyu sıçanların, özellikle karpal bölgeye odaklanan deneysel cerrahi modeller için uygun olmadığı sonucuna varılmıştır.

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Cite This Article

Üstündağ, Y., Koçak, Ü., Giousemoglou, B., Aydemir, M. A., Yakar, A. B. (2025). Functional Anatomy of the Carpal Region in Sprague Dawley Strain Rats. Kocatepe Veteriner Dergisi, Cilt: 18 Sayı: 4, 451–461. https://doi.org/10.30607/kvj.1639958

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