Journals / Harran Üniversitesi Veteriner Fakültesi Dergisi / 2026 / Volume: 15 Issue: 2

Clinical, Hematological and Surgical Evaluation of Calves with Congenital Intestinal Atresia: A Prospective Study

Kongenital İntestinal Atrezili Buzağılarda Klinik, Hematolojik Ve Operatif Yaklaşımların Prospektif Olarak Değerlendirilmesi

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Publication Date
2026-06-26
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These findings suggest that disseminated intravascular coagulation (DIC) may develop in calves with congenital intestinal atresia, leading to increased mortality.

📌 3 Key Takeaways

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Objective & Hypothesis:Congenital anomalies are frequently encountered in ruminants, and a substantial proportion of these abnormalities involve the digestive system.
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Key Findings & Data:A total of 60 calves diagnosed with Atresia coli and presented to the Veterinary Teaching Hospital of Adnan Menderes University were included in the study.
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Conclusion & Impact:These findings suggest that disseminated intravascular coagulation (DIC) may develop in calves with congenital intestinal atresia, leading to increased mortality.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Atresia coli calf · coagulation parameters · colostomy

Abstract

Congenital anomalies are frequently encountered in ruminants, and a substantial proportion of these abnormalities involve the digestive system. The present study aimed to prospectively evaluate the clinical, hematological, radiological, and surgical findings in calves diagnosed with congenital Atresia coli and to investigate the prognostic value of coagulation parameters. A total of 60 calves diagnosed with Atresia coli and presented to the Veterinary Teaching Hospital of Adnan Menderes University were included in the study. Blood samples were collected from the jugular vein for hematological analysis, blood gas analysis, and coagulation profiling. Radiographic examinations were performed using both direct and contrast techniques to determine the location of intestinal obstruction. Surgical treatment consisted primarily of a lateral colostomy. Among the calves included in the study, 78% were male, and 22% were female. Breed distribution revealed that 95% of the animals were Holstein and 5% were Montbéliarde. Lateral colostomy was performed in 13 calves. One calf died during surgery, three calves survived for at least 15 days postoperatively, and the remaining animals died within a short postoperative period. Hematological and coagulation analyses demonstrated significant increases in leukocyte and neutrophil counts as well as prolonged prothrombin time (PT) and activated partial thromboplastin time (APTT). These findings suggest that disseminated intravascular coagulation (DIC) may develop in calves with congenital intestinal atresia, leading to increased mortality.

Özet

Ruminantlarda kongenital anomali olgularıyla sıklıkla karşılaşıldığı ve bunların büyük bir bölümünü sindirim sistemi anomalilerinin oluşturduğu çeşitli araştırmacılar tarafından rapor edilmiştir. Kliniğimize getirilen ve çalışma kapsamına alınan 60 atresia koli’ li olguların preoperatif, intraoperatif ve postoperatif bulguları değerlendirilmiştir. Preoperatif laboratuvar analizleri kapsamında; buzağıların vena jugularisinden tam kan analizi amacıyla 2ml’lik EDTA’lı tüplere, kan gazları analizi için lityum heparin içeren kan gazı enjektörüne ve pıhtılaşma faktörleri (PT, APTT ve FİB) için 2 ml’lik sitratlı tüplere kan alınıp analiz edilmiştir. Analizler hemogram cihazı (Diatron Abacus Junior Vet 5), kan gazı cihazı (Irma Trupoint Kan Gazı Analizörü), koagulasyon cihazı(Bejing Precil 4 kanallı yarı otomatik koagülometre cihazı, Guanzgzhou) ile gerçekleştirildi. Elde edilen analiz sonuçları SPSS 22.0 istatistik programıyla değerlendirilmiş olup sağlıklı ve atresia koli’li buzağılar arasındaki farklılıklar Independent T- testi ile belirlenmiş, parametrelerin normal dağılım göstermemesi sebebiyle nonparametrik test olan Mann Whitney U testi ile değerlendirilmiştir. İstatistiksel en küçük anlamlılık düzeyi olarak p<0.05 kullanılmıştır. Çalışma kapsamına alınan 60 atresia koli’li buzağıların %78 inin erkek, %22 sinin dişi olduğu tespit edildi. Buzağıların %95 inin holstein, %5 inin montofon olduğu tespit edildi. Atresia koli’li 13 buzağıya kolostomi uygulanmıştır. Kolostomi operasyonu uygulanan 1 buzağı operasyon sırasında ölmüş, 3 buzağının 15 gün sonrasında yaşadığı ve geri kalan 9 buzağının postoperatif kısa sürede öldüğü tespit edilmiştir. Sağlıklı ve atresia koli’li buzağıların hematolojik, biyokimyasal ve koagulasyon parametreleriyle birlikte postoperatif hayatta kalma indeksleri değerlendirildiğinde; PT ve APTT’ nin uzadığı durumlarda DIC oluşabileceği buna bağlı olarakta anomalili buzağılarda mortaliteyi arttırarak prognozu ciddi anlamda etkilediği belirlenmiştir. Koagulasyon faktörlerinin preoperatif değerlendirilmesinin atresia koli’li buzağılarda prognostik olarak önemli olabileceği kanısına varılmıştır.

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Cite This Article

Kılıç, N., Zilci, İ. (2026). Clinical, Hematological and Surgical Evaluation of Calves with Congenital Intestinal Atresia: A Prospective Study. Harran Üniversitesi Veteriner Fakültesi Dergisi, Volume: 15 Issue: 2. https://doi.org/10.31196/huvfd.1911213

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