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Journals / Hacettepe Üniversitesi Sağlık Bilimleri Fakültesi Dergisi / 2026 / Volume: 13 Issue: 2

Effects of Gluten-Free Diet on Nutritional Status and Some Inflammation Parameters in Adult Celiac Disease Patients

Öznur Aydın(HACETTEPE ÜNİVERSİTESİ, SAĞLIK BİLİMLERİ FAKÜLTESİ, BESLENME VE DİYETETİK BÖLÜMÜ)0000-0001-8463-6660
Evrim Kahramanoğlu Aksoy(Sağlık Bilimleri Üniversitesi, Atatürk Sanatoryum Eğitim ve Araştırma Hastanesi, Gastroenteroloji Bölümü)0000-0001-8887-3428
Zeynep Göktaş(HACETTEPE ÜNİVERSİTESİ, SAĞLIK BİLİMLERİ FAKÜLTESİ, BESLENME VE DİYETETİK BÖLÜMÜ)0000-0001-7241-8017
Pages
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Publication Date
2026-08-28
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Gluten-free diet education positively impacts nutritional status, diet adherence, and quality of life in celiac patients.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Celiac disease is a lifelong autoimmune disorder in which strict adherence to a gluten-free diet is the cornerstone of treatment.
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Key Findings & Data:This study aims to examine the effect of a gluten-free diet on nutritional status, anthropometric measurements, and serum interferon-gamma and interleukin-15 levels in adult celiac patients Materials and Methods: Twenty-one adult female celiac patients and 20 healthy controls were included.
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Conclusion & Impact:Conclusion: Gluten-free diet education positively impacts nutritional status, diet adherence, and quality of life in celiac patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Celiac · Nutritional status · Gluten-free diet

Abstract

Objectives: Celiac disease is a lifelong autoimmune disorder in which strict adherence to a gluten-free diet is the cornerstone of treatment. However, many patients follow the gluten-free diet incorrectly due to limited nutrition education, which may affect nutritional adequacy, inflammation, and quality of life. This study aims to examine the effect of a gluten-free diet on nutritional status, anthropometric measurements, and serum interferon-gamma and interleukin-15 levels in adult celiac patients Materials and Methods: Twenty-one adult female celiac patients and 20 healthy controls were included. All celiac patients received a structured, individualized gluten-free diet education session at baseline. Nutritional intake, anthropometric measurements, cytokine levels, and quality of life were assessed at baseline and after six weeks. Comparisons were made between baseline and week 6 within the celiac group, and between the celiac and control groups. Results: Interleukin-15 levels showed no significant differences, while interferon-gamma levels were higher in celiac patients but decreased after six weeks. Adherence to a gluten-free diet improved significantly at the 6th week. At baseline in the celiac group, protein (g/kg), fiber, thiamin, niacin, and iron intakes were significantly lower. In the 6th week, the levels of nutrient intakes except thiamin reached similar levels between the groups. The quality-of-life scores of celiac patients also increased significantly. Conclusion: Gluten-free diet education positively impacts nutritional status, diet adherence, and quality of life in celiac patients.

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Cite This Article

Aydın, Ö., Aksoy, E. K., Göktaş, Z. (2026). Effects of Gluten-Free Diet on Nutritional Status and Some Inflammation Parameters in Adult Celiac Disease Patients. Hacettepe Üniversitesi Sağlık Bilimleri Fakültesi Dergisi, Volume: 13 Issue: 2. https://doi.org/10.21020/husbfd.1848344

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