SavedAdd your journal

Journals / Güncel Pediatri / 2026 / Cilt: 16 Sayı: 2

Short-Term Clinical Outcomes of Newborns Who Have Neural Tube Defects

Nöral Tüp Defektli Yenidoğanların Kısa Dönem Sonuçları Short-Term Clinical Outcomes of Newborns Who Have Neural Tube Defects

Salih Çağrı Çakır
Bayram Ali Dorum
Hilal Özkan
Özgür Taşkapılıoğlu
Nilgün Köksal
Rabia Tütüncü Toker
Mehmet Sait Okan
Pages
117–126
Publication Date
2018-08-01
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

NTD olan hastaların uzun dönem medikal, cerrahi ve bakım desteği ihtiyacı vardır.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:GİRİŞ ve AMAÇ: Nöral tüp defektleri (NTD) yenidoğanlarda en sık saptanan konjenital anomalilerden biridir.
📊
Key Findings & Data:Türkiyedeki görülme sıklığı 3/1000’dir.
💡
Conclusion & Impact:NTD olan hastaların uzun dönem medikal, cerrahi ve bakım desteği ihtiyacı vardır.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Nöral tüp defektleri · meningosel · meningomiyolesel

Özet

GİRİŞ ve AMAÇ: Nöral tüp defektleri (NTD) yenidoğanlarda en sık saptanan konjenital anomalilerden biridir. Türkiyedeki görülme sıklığı 3/1000’dir. NTD’lerin etiyolojisi multifaktöriyel olup önemli bir kısmının folik asit desteği ile önlenebilmesi mümkündür. NTD olan hastaların uzun dönem medikal, cerrahi ve bakım desteği ihtiyacı vardır.

🔖

Cite This Article

Çakır, S. Ç., Dorum, B. A., Özkan, H., Taşkapılıoğlu, Ö., Köksal, N., Toker, R. T., Okan, M. S. (2018). Short-Term Clinical Outcomes of Newborns Who Have Neural Tube Defects. Güncel Pediatri, Cilt: 16 Sayı: 2, 117–126. https://ajindex.com/articles/1400917

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Greene NDE, Copp AJ. Neural Tube Defects. Annu Rev Neurosci. 2014;37:221–42.
  2. Murat A, Aras M, Altaş ZG, Aras Z, Seraslan Y, Yılmaz N. Nöral Tüp Defektli Hastalara Retrospektif Bakış. Mustafa Kemal Üniversitesi Tıp Derg. 2012;3(9):22–8.
  3. Tunçbilek E. Türkiye’deki yüksek nöral tüp defekti sıklığı ve önlemek için yapılabilecekler. Çocuk Sağlığı ve Hast Derg. 2004;47:79–84.
  4. American College of Obstetricians and Gynecologists. Neural tube defects. Practice Bulletin No. 187. Obstet Gynecol. 2017;130(6):e279–90.
  5. Castillo-Lancellotti C, Tur JA, Uauy R. Impact of folic acid fortification of flour on neural tube defects: A systematic review. Public Health Nutr. 2013;16(5):901–11.
  6. Prakash, Prabhu L V., Nasar MA, Rai R, Madhyastha S, Singh G. Lamotrigine in pregnancy: Safety profile and the risk of malformations. Singapore Med J. 2007;48(10):880–3.
  7. Karaca NE, Karaca E, Onay H, Gunduz C, Egemen A, Ozkinay F. Evaluation of mothers’ MTHFR genotype and other risk factors of neural tube defects in their children. Ege J Med.2012;51(1):37–42.
  8. Meng X, Sun Y, Duan W, Jia C. Meta-analysis of the association of maternal smoking and passive smoking during pregnancy with neural tube defects. Int J Gynaecol Obs [Internet]. 2018;140:18–25. Available from: http://doi.wiley.com/10.1002/ijgo.12334
  9. Toriello H V, Higgins J V, Opitz JM. Occurrence of neural tube defects among first-, second and third-degree relatives of probands: results of a United States study. Am J Med Genet [Internet]. 1983 Aug [cited 2018 Feb 7];15(4):601–6.
  10. Wilson RD, Audibert F, Brock JA, Carroll J, Cartier L, Gagnon A, et al. Pre-conception Folic Acid and Multivitamin Supplementation for the Primary and Secondary Prevention of Neural Tube Defects and Other Folic Acid-Sensitive Congenital Anomalies. J Obstet Gynaecol Canada. 2015;37(6):534–49.
  11. Honein MA, Paulozzi LJ, Mathews TJ, Erickson JD, Wong LYC. Impact of folic acid fortification of the US food supply on the occurrence of neural tube defects. JAMA [Internet]. 2001 Jun 20 [cited 2018 Feb 7];285(23):2981–6.
  12. American College of Obstetricians and Gynecologists. Ultrasound in pregnancy. Practice Bulletin No. 175. Obstet Gynecol. 2016;128(6):1459–60.
  13. Sibinski M, Synder M, Higgs ZCJ, Kujawa J, Grzegorzewski A. Quality of life and functional disability in skeletally mature patients with myelomeningocele-related spinal deformity. JPediatr Orthop Part B. 2013;22(2):106–9.
  14. Bowman RM, McLone DG, Grant JA, Tomita T, Ito J. Spina Bifida Outcome: A 25-year Prospective. Pediatr Neurosurg. 2001;34(3):114–20.
  15. Meuli M, Meuli-Simmen C, Hutchins GM, Seller MJ, Harrison MR, Adzick NS. The spinal cord lesion in human fetuses with myelomeningocele: Implications for fetal surgery. J Pediatr Surg. 1997;32(3):448–52.