Journals / Çukurova Anestezi ve Cerrahi Bilimler Dergisi / 2023 / Cilt: 6 Sayı: 3

The Role of Corynebacterium in The Etiology of Granulomatous Mastitis

Pages
449–452
Publication Date
2023-12-31
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Additionally studies with large case series are needed to explain the etiology.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Introduction: Granulomatous mastitis (GM) is a rare, benign, chronic inflammatory illness of the breast.
📊
Key Findings & Data:Material and Methods: In this study, we retrospectively analyzed the results of 201 breast tru-cut biopsies carry out for diagnostic purposes in the Department of General Surgery.
💡
Conclusion & Impact:Additionally studies with large case series are needed to explain the etiology.
🔬Design:Klinik Araştırma
📍Scope:Comprehensive Sample
⚙️Variables:Mastitis · Corynebacterium · Granulomatous Mastitis.

Abstract

Introduction: Granulomatous mastitis (GM) is a rare, benign, chronic inflammatory illness of the breast. It is characterized by necrotizing granulomatous lobulitis of the breast that clinically mimics breast cancer. The aim of this study was to examine the existence of Corynebacterium strains thought to be covered in the etiology of idiopathic granulomatous mastitis. Material and Methods: In this study, we retrospectively analyzed the results of 201 breast tru-cut biopsies carry out for diagnostic purposes in the Department of General Surgery. The tissue samples of 41 patients with histopathologically diagnosed GM were examined by Gram staining. The existence of Corynebacterium kinds was investigated microscopically by adding appropriate medium. Results: The mean age of 41 female patients with GM was 35. 7 years and the age range was 20-58 years. At the end of the study, Corynebacterium amycolatum was defined as the causative microorganism as a consequence of microbiologic examination of the tissue sample of one patient (2.4%). Conclusion: We consider that Corynebacterium is not the etiologic agent of GM. Additionally studies with large case series are needed to explain the etiology.

🔖

Cite This Article

Yaman, G., Girgin, S., Akpolat, N., Uzuner, N., Yildizhan, E. (2023). The Role of Corynebacterium in The Etiology of Granulomatous Mastitis. Çukurova Anestezi ve Cerrahi Bilimler Dergisi, Cilt: 6 Sayı: 3, 449–452. https://doi.org/10.36516/jocass.1358550

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (23)

  1. ErhanY, Veral A, Kara E, et al. A clinicopathologic study of a rare clinical entity mimicking breast carcinoma: idiopathic granulomatous mastitis. The Breast. 200,0; 9(1): 52-6. https://doi.org/10.1054/brst.1999.0072
  2. Imoto S, Kitaya T, Kodama T, et al. Idiopathic Granulomatous Mastitis: Case Report and Review of the Literature, Japanese Journal of Clinical Oncology. 1997; 27(4): 274-7. https://doi.org/10.1093/jjco/27.4.274
  3. Schelfout K, Tjalma WA, Cooremans ID, et al. Observations of an idiopathic granulomatous mastitis. Eur J Obstet Gynecol Reprod Biol. 2001;97(2):260-7. https://doi.org/10.1016/s0301-2115(00)00546
  4. Dobinson HC, Anderson TP, Chambers ST, et al. Antimicrobial Treatment Options for Granulomatous Mastitis Caused by Corynebacterium Species. J Clin Microbiol. 2015; 53(9): 2895-9. https://doi.org/10.1128/JCM.00760-15
  5. Gautier N, Lanolde L, Tran-Tranh D, et al. Chronic Granulomatous Mastitis: Imaging, Pathology and Management, European Journal of Radiology. 2013; 82 (4): e165-75. https://doi.org/10.1016/j.ejrad.2012.11.010
  6. Al-Khaffaf B, Knox F, Bundred, NJ. Idiopathic granulomatous mastitis: a 25-year experience. J Am Coll Surg. 2008; 206(2): 269-73. https://doi.org/10.1016/j.jamcollsurg.2007.07.041
  7. ShinYD, Park SS, Song YJ, et al. Is surgical excision necessary for the treat-ment of Granulomatous lobular mastitis? BMC Womens Health. 2017; 17 (1): 49. https://doi.org/10.1186/s12905-017-0412-0
  8. Bani-Hani KE, Yaghan RJ, Matalka II, et al. Idiopathic granulomatous mas-titis: Time to avoid unnecessary mastectomies. Breast J. 2004; 10 (4): 318-22. https://doi.org/10.1111/j.1075-122X.2004.21336.x
  9. Gi̇rgi̇n S, Uslukaya O, Yılmaz E, et al. Granulomatous mastitis: A retrospec¬tive review of 49 patients. Dicle Medical Journal. 2015; 42(1): 22-7. https://doi.org/10.5798/diclemedj.0921.2015.01.0524
  10. Ozel L, Unal A, Unal E, et al. Granulomatous mastitis: is it an autoimmune disease? Diagnostic and therapeutic dilemmas. Surg Today. 2012; 42(8): 729-33. https://doi.org/10.1007/s00595-011-0046-z
  11. Li J. Diagnosis and Treatment of 75 Patients with Idiopathic Lobular Gran¬ulomatous Mastitis. J Invest Surg. 2019; 32(5): 414-20. https://doi.org/10.1080/08941939.2018.1424270
  12. Ozşen M, Tolunay Ş, Gökgöz MŞ. Granulomatous Lobular Mastitis: Clini-copathologic Presentation of 90 Cases. Recurrence in Uterine Tumors with Ovarian Sex-Cord Tumor Resemblance: A Case Report and Systematic Re¬view. Türk Patoloji Derg. 2018; 34(3): 215-9. https://doi.org/10.5146/tjpath.2018.01431
  13. Agarwal C, Singh K, Pujani M, et al. Are all Granulomatous Mastitis Cases Tuberculous?: A Study on the Role of Cytology in Evaluation of Granuloma¬tous Mastitis. Are all Granulomatous Mastitis Cases Tuberculous?: A Study on the Role of Cytology in Evaluation of Granulomatous Mastitis. Türk Patoloji Derg. 2019; 35(2): 128-33. https://doi.org/10.5146/tjpath.2018.01442
  14. Chandanwale S, Naragude P, Shetty A, et al. Cytomorphological Spectrum of Granulomatous Mastitis: A Study of 33 Cases. Eur J Breast Health. 2020; 16(2): 146-51. https://doi.org/10.5152/ejbh.2020.5185
  15. Prasad S, Jaiprakash P, Dave A, et al. Idiopathic granulomatous mastitis: an institutional experience. Turk J Surg. 2017; 33(2): 100-3. https://doi.org/10.5152/turkjsurg.2017.3439
  16. Wolfrum A, Kümmel S, Theuerkauf I, et al. Granulomatous Mastitis: A Therapeutic and Diagnostic Challenge. Breast Care (Basel). 2018;13(6): 413-8. https://doi.org/10.1159/000495146
  17. Shoyele O, Vidhun R, Dodge J, et al. Cystic neutrophilic granulomatous mastitis: A clinicopathologic study of a distinct entity with supporting evi¬dence of a role for Corynebacterium-targeted therapy. Ann Diagn Pathol. 2018; 37: 51-6. https://doi.org/10.1016/j.anndiagpath.2018.08.005
  18. Taylor GB, Paviour SD, Musaad S, et al. A clinicopathological review of 34 cases of inflammatory breast disease showing an association between corynebacteria infection and granulomatous mastitis. Pathology. 2003; 35(2): 109-9. https://linkinghub.elsevier.com/retrieve/pii/8WYF41619LM9YKP
  19. Renshaw AA, Derhagopian RP, Gould EW. Cystic neutrophilic granuloma¬tous mastitis: an underappreciated pattern strongly associated with gram-positive bacilli. Am J Clin Pathol 2011; 136(3): 424–7. https://doi.org/10.1309/AJCP1W9JBRYOQSNZ
  20. Kıvılcım T, Altıntoprak F, Memiş B, et al. Role of Bacteriological Agents in Idiopathic Granulomatous Mastitis: Real or Not? Eur J Breast Health. 2018; 15(1): 32-6. https://doi.org/10.5152/ejbh.2018.4249
  21. Taylor GB, Paviour SD, Musaad S, et al. A clinicopathological review of 34 cases of inflammatory breast disease showing an association between corynebacteria infection and granulomatous mastitis. Pathology. 2003; 35(2): 109-9. https://linkinghub.elsevier.com/retrieve/pii/8WYF41619LM9YKP
  22. Paviour S, Musaad S, Roberts S, et al. Corynebacterium species isolated from patients with mastitis. Clin Infect Dis. 2002; 35(11): 1434-40. https://doi.org/10.1086/344463
  23. Butta H, Pasha F, Dawar R, et al. Corynebacterium Amycolatum Causing Breast Abscess: An Infecting Diphtheroid with a difference. Annals of Pathol¬ogy and Laboratory Medicine. 2017; 4: 128-30. https://doi.org/10.21276/APALM.1456