Journals / Çukurova Anestezi ve Cerrahi Bilimler Dergisi / 2026 / Cilt: 7 Sayı: 3

Predicting Acute Pancreatitis Severity: A Comparative Analysis of Computed Tomography Severity Index, Including Fat and Muscle Parameters

Gorkem Ozdemir(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ADANA ŞEHİR SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-2335-1538
Burçak Çakır Peköz(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ADANA ŞEHİR SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-7286-5535
Alper Sözütek(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ADANA ŞEHİR SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0003-1039-9011
Ahmet Şeker(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ADANA ŞEHİR SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-6722-7838
Pages
165–169
Publication Date
2024-09-30
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⚡ TL;DR(Too Long; Didn't Read)

Conclusions: In this study, our study suggested that computed tomography -measured fat and muscle parameters did not significantly improve the accuracy of computed tomography severity index in predicting severity of acute pancreatitis.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: The aim of this study was to investigate whether computed tomography-measured intra-abdominal fat and muscle parameters could improve the accuracy of acute pancreatitis severity assessment using the computed tomography severity index.
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Key Findings & Data:Methods: This retrospective study included clinical and imaging parameters of 87 patients with acute pancreatitis.
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Conclusion & Impact:Conclusions: In this study, our study suggested that computed tomography -measured fat and muscle parameters did not significantly improve the accuracy of computed tomography severity index in predicting severity of acute pancreatitis.
🔬Design:Klinik Araştırma
📍Scope:Comprehensive Sample
⚙️Variables:acute pancreatitis · atlanta classification · computed tomography

Abstract

Aim: The aim of this study was to investigate whether computed tomography-measured intra-abdominal fat and muscle parameters could improve the accuracy of acute pancreatitis severity assessment using the computed tomography severity index. Methods: This retrospective study included clinical and imaging parameters of 87 patients with acute pancreatitis. Patients were assessed by the computed tomography severity index. Asan J-Morphometry (Seoul, Korea), an ImageJ-based software (NIH, USA), was used to quantify abdominal muscle and fat areas. Total fat area, superficial fat area, visceral fat area, total muscle area and total muscle-fat area were calculated. The severity of acute pancreatitis was determined according to the revised Atlanta classification. Interreader agreement assessments, univariate and multivariate analyses were performed. Results: No significant differences were found in intra-abdominal fat and muscle parameters between groups with or without systemic or local complications (p > 0.05). When the patients were categorized as mild and severe disease based on computed tomography severity index score, no significant differences were found in fat and muscle parameters (p > 0.05). Surgery, systemic complications, and a high total computed tomography severity index score significantly increased the risk of local complications, with odds ratios of 0.001, 141.9, and 2.42, respectively. The intraclass correlation coefficients (ICC) were ≥ 0.90 between the readers. Conclusions: In this study, our study suggested that computed tomography -measured fat and muscle parameters did not significantly improve the accuracy of computed tomography severity index in predicting severity of acute pancreatitis.

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Cite This Article

Ozdemir, G., Peköz, B. Ç., Sözütek, A., Şeker, A. (2024). Predicting Acute Pancreatitis Severity: A Comparative Analysis of Computed Tomography Severity Index, Including Fat and Muscle Parameters. Çukurova Anestezi ve Cerrahi Bilimler Dergisi, Cilt: 7 Sayı: 3, 165–169. https://doi.org/10.36516/jocass.1504840

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References (18)

  1. Janisch NH, Gardner TB. Advances in Management of Acute Pancreatitis. Gastroenterol Clin North Am. 2016; 45(1):1-8. https://doi.org/10.1016/j.gtc.2015.10.004
  2. Ghelfi J, Thony F, Frandon J, et al. Gastrointestinal bleeding due to pancreatitis-induced splenic vein thrombosis: Treatment with percutaneous splenic vein recanalization. Diagn Interv Imaging. 2016; 97(6):677-9. https://doi.org/10.1016/j.diii.2016.01.005
  3. Forsmark CE, Vege SS, Wilcox CM. Acute Pancreatitis. N Engl J Med. 2016; 375(20):1972-81. https://doi.org/10.1056/NEJMra1505202
  4. Balthazar EJ, Robinson DL, Megibow AJ, et al. Acute pancreatitis: value of CT in establishing prognosis. Radiology. 1990; 174(2):331-6. https://doi:10.1148/radiology.174.2.2296641
  5. Balthazar EJ. Acute pancreatitis: assessment of severity with clinical and CT evaluation. Radiology. 2002; 223(3):603-13. https://doi.org/10.1148/radiol.2233010680
  6. Simchuk EJ, Traverso LW, Nukui Y, et al. Computed tomography severity index is a predictor of outcomes for severe pancreatitis. Am J Surg. 2000; 179(5):352. https://doi.org/10.1016/s0002-9610(00)00375-5
  7. Valverde-López F, Matas-Cobos AM, Alegría-Motte C, et al. BISAP, RANSON, lactate and others biomarkers in prediction of severe acute pancreatitis in a European cohort. J Gastroenterol Hepatol. 2017; 32(9):1649-56. https://doi.org/10.1111/jgh.13763
  8. Madico C, Herpe G, Vesselle G, et al. Intra peritoneal abdominal fat area measured from computed tomography is an independent factor of severe acute pancreatitis. Diagn Interv Imaging. 2019; 100(7-8):421-6. https://doi:10.1016/j.diii.2019.03.008
  9. Monreal-Robles R, Kohn-Gutiérrez AE, Sordia-Ramírez J, et al. Peritoneal cavity circumference on computed tomography predicts outcomes in acute pancreatitis. Eur J Radiol. 2020; 132:109327. https://doi.org/10.1016/j.ejrad.2020.109327
  10. Schweitzer L, Geisler C, Pourhassan M, et al. What is the best reference site for a single MRI slice to assess whole-body skeletal muscle and adipose tissue volumes in healthy adults? Am J Clin Nutr. 2015; 102(1):58-65. https://doi.org/10.3945/ajcn.115.111203
  11. Gupta P, Dawra S, Chandel K, et al. Fat-modified computed tomography severity index (CTSI) is a better predictor of severity and outcome in patients with acute pancreatitis compared with modified CTSI. Abdom Radiol (NY). 2020; 45(5):1350-8.https://doi.org/10.1007/s00261-020-02473-y
  12. Lin C, Zhang J, Wang C, et al. The impact of skeletal muscle index at the third lumbar spine on nosocomial deterioration and short-term prognosis in acute pancreatitis: a retrospective observational study. PeerJ. 2024;12:e17283. https://doi.org/10.7717/peerj.17283
  13. Wang S, Wang M, Jiang L, et al. Low skeletal muscle quality extracted from CT is associated with poor outcomes in severe acute pancreatitis patients. Eur J Radiol. 2024;170:111215. https://doi.org/10.1016/j.ejrad.2023.111215
  14. Fu H, Li P, Xing Q, et al. Cutoff Value of Psoas Muscle Area as Reduced Muscle Mass and Its Association with Acute Pancreatitis in China. Int J Gen Med. 2023;16:2733-51. https://doi.org/10.2147/IJGM.S413308
  15. Dawra S, Gupta P, Yadav N, et al. Association between the Distribution of Adipose Tissue and Outcomes in Acute Pancreatitis: A Comparison of Methods of Fat Estimation. Indian J Radiol Imaging. 2022; 33(1):12-8. https://doi.org/10.1055/s-0042-1758201
  16. Working Party of the British Society of Gastroenterology; Association of Surgeons of Great Britain and Ireland; Pancreatic Society of Great Britain and Ireland; Association of Upper GI Surgeons of Great Britain and Ireland. UK guidelines for the management of acute pancreatitis. Gut. 2005; 54 Suppl 3(Suppl 3):iii1-9. https://doi.org/10.1136/gut.2004.057026 17.Yokoe M, Takada T, Mayumi T, et al. Japanese guidelines for the management of acute pancreatitis: Japanese Guidelines 2015. J Hepatobiliary Pancreat Sci. 2015; 22(6):405-32. https://doi.org/10.1002/jhbp.259
  17. Toouli J, Brooke-Smith M, Bassi C, et al; Working Party of the Program Commitee of the Bangkok World Congress of Gastroenterology 2002. Guidelines for the management of acute pancreatitis. J Gastroenterol Hepatol. 2002; 17 Suppl:S15-39. https://doi.org/10.1046/j.1440-1746.17.s1.2.x
  18. Higaki Y, Nishida T, Matsumoto K, et al. Effect of abdominal visceral fat on mortality risk in patients with severe acute pancreatitis. JGH Open. 2021; 5(12):1357-62. https://doi.org/10.1002/jgh3.12681