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Journals / Batı Karadeniz Tıp Dergisi / 2026 / Cilt: 6 Sayı: 1

Is Vitamin D Level Associated with COVID-19 Infection?

D Vitamini Düzeyi COVID-19 Enfeksiyonu ile İlişkili midir?

Fatih Okan(TOKAT GAZIOSMANPASA UNIVERSITY, FACULTY OF HEALTH SCIENCES)0000-0002-7544-9051
Sevil Okan(Tokat Public Hospital)0000-0002-0446-6866
Yasemin Hanoğlu(Tokat Public Hospital)0000-0002-3740-2068
Pages
48–52
Publication Date
2022-04-28
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: It was found that 86.5% of the study participants had vitamin D deficiency.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: The effects of vitamin D, which has an antiviral and immune modulator in preventing the rapidly spreading COVID-19, which has been resulting in increasing number of deaths worldwide, is discussed.
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Key Findings & Data:The aim of the present study was to determine whether 25-hydroxyvitamin D level is associated with COVID-19 risk.
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Conclusion & Impact:Results: It was found that 86.5% of the study participants had vitamin D deficiency.
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:25(OH) D · COVID-19 · D vitamini durumu

Abstract

Aim: The effects of vitamin D, which has an antiviral and immune modulator in preventing the rapidly spreading COVID-19, which has been resulting in increasing number of deaths worldwide, is discussed. The aim of the present study was to determine whether 25-hydroxyvitamin D level is associated with COVID-19 risk. Material and Methods: Ninety-six individuals (48 COVID-19 positive and 48 COVID-19 negative) were included in this cross-sectional study. Data were collected with a questionnaire form evaluating the individual and clinical characteristics of the study participants, their eating habits affecting vitamin D status and their sun exposures. 25-hydroxyvitamin D measurements and polymerase chain reaction test results were evaluated. Independent samples t test was used to compare the age, BFUI and vitamin D levels of the patient and control groups while Chi-square and Fisher’s exact test were used for the ratio comparisons of categorical variables. Results: It was found that 86.5% of the study participants had vitamin D deficiency. There was no significant difference between 25-hydroxyvitamin D levels of individuals who tested positive for COVID-19 and those who did not (11.50 ± 6.66 ng/ml and 12.95 ± 6.11 ng/ml, respectively, p = 0.271). Vitamin D status (severely deficient, deficient, insufficient) was similar in those with and without COVID-19 infection (p = 0.586). Conclusion: Our findings do not support the potential link between COVID-19 infection risk and 25-hydroxyvitamin D level or vitamin D status.

Özet

Amaç: Antiviral ve immün modülatör etkisi olan D vitamininin, dünya çapındaki artan ölüm sayısıyla birlikte hızla yayılan COVID-19’u önlemedeki etkisi tartışılmaktadır. Çalışmanın amacı 25-hidroksivitamin D düzeyinin COVID-19 riski ile ilişkili olup olmadığının belirlenmesidir. Gereç ve Yöntemler: Kesitsel tipteki çalışmaya 96 birey (48 COVID-19 pozitif ve 48 COVID-19 negatif) dahil edildi. Çalışmaya katılanların bireysel ve klinik özelliklerini, D vitamini durumlarını etkileyen beslenme alışkanlıklarını ve güneş maruziyetlerini değerlendiren anket formu ile veriler toplandı. 25-hidroksivitamin D düzeyi ölçümleri ve Polimeraz Zincir Reaksiyonu test sonuçları değerlendirildi. Bulgular: Çalışmaya katılanların %86,5’inde D vitamini eksikliği olduğu bulundu. Çalışmada COVID-19 testi pozitif olan ve olmayan bireylerin 25-hidroksivitamin D düzeyi ortalamaları arasında istatistiksel olarak anlamlı fark bulunmadı (sırasıyla 11,50 ± 6,66 ng/ml, 12,95 ± 6,11 ng/ ml, p = 0,271). D vitamini durumu (ciddi eksiklik, eksiklik, yetersizlik) COVID -19 enfeksiyonu olan ve olmayanlar arasında benzer bulundu (p = 0,586). Hasta ve kontrol gruplarının yaşı, BFUI ve D vitamini düzeylerinin karşılanmasında iki ortalama arasındaki farkın önemlilik testi; kategorik değişkenlerin oran karşılaştırmaları için Ki-kare ve Fisher’in kesin testi kullanıldı. Sonuç: Bulgularımız 25- hidroksivitamin D düzeyi ve D vitamini durumu ile COVID-19 enfeksiyonu riski arasında potansiyel bağlantıyı desteklememektedir.

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Cite This Article

Okan, F., Okan, S., Hanoğlu, Y. (2022). Is Vitamin D Level Associated with COVID-19 Infection?. Batı Karadeniz Tıp Dergisi, Cilt: 6 Sayı: 1, 48–52. https://doi.org/10.29058/mjwbs.1059760

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