AI Summary & Key Takeaways
AI InsightThese changes were found in all cases except one, that case had nonpurulent encephalitis.
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Abstract
This study was based 011 hydranencephalic 22 calves. These calves were obtained Ji'om the provinces of Antalya and İçel during an epizootic period in ı985. The serum neutralizing antibodies against Akabane virus were detected in eighteen blood sera tak en from hydranencepha/ic calves and their mothers by Pirbright Animal Virus Resem'dı Institute (A VRI) in England. Pozitive results for bluetongue virus were also determined in eight of eighteen sera using ELISA. In addition, the bluetongue virus was isolated Ji'om the' blood of two hydranencepha/ic calves by Etlik Animal Disease Research Institute (ADRI) in Turkey. These isolates were identifieel as bluetongue virus serotype 4 by Pirbright AVRI. None the calves showed any remarkable clinical symptoms except b/indness. Macroscopical/y, hemispheres were fil/ed with various amounts of cerebrospinal fluid (CSF). The brain stems were normal in appearance. Changes due to compression were noticed in the thalamus. corpus striatum, hippocampus, tectum mesencephaly and cerebel/um. The displacement and hypoplasia of the pineal body were encountered in two different calves. Obstructioll of the third ventricle due to precipitation of calcium salts was observed in one ca/f. The other macroscopical findings were cystic septum pellucidum, defect of the septum pellucidum and partial absence of the corpus cal/osum. Microscopically, narrow residual hemispheric tissues were scierotic in appearance, although the relatively large tissues had normal histologic strııctures and some areas of residual tissues were composed of only leptomeninges. Generally, residual hemispheric tissues had narrow substantia a/ba protruding to the membranous sacs due to gliosis. Sclerotic appearances were also observed in the promontorium gliosum calami scriptorU of the medulla oblongata in almost all of the cases. The other microscopical findings were subependymal rosettes, gliosis, subcOl.tical cavitations and mild perivascular cujfings. Myelination was normal. These changes were found in all cases except one, that case had nonpurulent encephalitis.