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Journals / Ankara Medical Journal / 2018 / Cilt: 18 Sayı: 4

Is There a Relationship between Clinical Symptoms of Asthmatic Children and Serum Levels of Vitamin D and Zinc?

Astımlı Çocukların Serum D Vitamini ve Çinko Düzeyleri ile Klinik Bulguları Arasında Bir İlişki Var mı?

Zehra Şule Haskoloğlu
Demet Altun
Pages
528–536
Publication Date
2018-12-27
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion : Our results showed that asthmatic children had lower vitamin D and zinc levels than healthy children.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives : It is reported that deficiencies in vitamin D and zinc are associated with asthma.
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Key Findings & Data:Materials and Methods : This prospective study included a total of 149 asthmatics and 97 healthy children with an age range of 5 to 17 years.
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Conclusion & Impact:Conclusion : Our results showed that asthmatic children had lower vitamin D and zinc levels than healthy children.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Astımlı çocuk · vitamin D düzeyi · çinko düzeyi

Abstract

Objectives : It is reported that deficiencies in vitamin D and zinc are associated with asthma. In this study we aimed to investigate the relationship between clinic findings of asthmatic children and vitamin D and zinc levels. Materials and Methods : This prospective study included a total of 149 asthmatics and 97 healthy children with an age range of 5 to 17 years. All of the participants were evaluated for serum levels of 25 -hydroxyvitamin D (25(OH)D) and zinc, dietary habits, the rate of respiratory tract infections, hospital visits and levels of sunlight exposure. Results : Serum vitamin D and zinc levels in asthmatic children (7.7±5.29 ng/ml), (64±16.3 mcg/dl) were significantly lower than that in healthy children (12.3±12.87 ng/ml), (69±26.2 mcg/dl) (p< 0.015), respectively. A relationship was detected between the frequency of infection and vitamin D level’s being <10ng/ml (p < 0.001), while no relationship was detected between the frequency of infection and zinc level. No relationship was detected between pulmonary function, nutrition and the levels of vitamin D and zinc. However, a relationship was detected between vitamin D levels and exposure to sunlight. Conclusion : Our results showed that asthmatic children had lower vitamin D and zinc levels than healthy children. Very low levels of vitamin D were found to be associated with an increased rate of infection and required more medication and hospitalization

Özet

Amaç: Vitamin D ve çinko eksikliğinin astım ile ilişkili olduğu bildirilmektedir. Bu çalışmada astımlı çocukların klinik bulguları ile vitamin D ve çinko düzeyleri arasındaki ilişkiyi araştırmayı istedik. Materyal ve Metot: Bu prospektif çalışmaya yaşları 5‐17 arasında değişen 149 astımlı ve 97 sağlıklı çocuk dahil edildi. Tüm katılımcıların serum 25 hidroksivitamin D (25(OH)D) ve çinko düzeyleri ölçüldü, diyet alışkanlıkları, bir yıldaki solunum yolu enfeksiyonu sıklıkları, hastane başvuruları ve güneş ışığına maruziyet süreleri sorgulandı. Bulgular: Astımlı çocukların serum D vitamini ve çinko düzeyleri sırasıyla (7,7±5,29 ng/ml), (64±16,3 mcg/dl) sağlıklı çocuklardan (12,3±12,87 ng/ml), (69±26,2 mcg/dl) belirgin şekilde düşük bulundu (p <0,001) (p <0,015). Serum D vitamini düzeyinin 10ng/ml'nin altında olması ile enfeksiyon sıklığı arasında ilişki bulunurken çinko düzeyi ile ilişki saptanmadı. Pulmoner fonksiyonlar, beslenme ile D vitamini düzeyi arasında ilişki saptanmadı. Ancak güneşe maruziyet ile D vitamini düzeyi arasında bir ilişki saptandı. Sonuç: Sonuç: Bizim sonuçlarımız astımlı çocukların sağlıklı çocuklardan daha düşük D vitamini ve çinko düzeyine sahip olduğunu göstermektedir. D vitamininin çok düşük düzeylerde olması artmış enfeksiyon riski, daha çok tedavi ihtiyacı ve hastane yatışı ile ilişkili ulundu.

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Cite This Article

Haskoloğlu, Z. Ş., Altun, D. (2018). Is There a Relationship between Clinical Symptoms of Asthmatic Children and Serum Levels of Vitamin D and Zinc?. Ankara Medical Journal, Cilt: 18 Sayı: 4, 528–536. https://doi.org/10.17098/amj.499653

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