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Journals / Ankara Medical Journal / 2018 / Cilt: 18 - Sayı: 4

Is There a Relationship between Clinical Symptoms of Asthmatic Children and Serum Levels of Vitamin D and Zinc?

Astımlı Çocukların Serum D Vitamini ve Çinko Düzeyleri ile Klinik Bulguları Arasında Bir İlişki Var mı?

Demet ALTUN
Zehra Şule HASKOLOĞLU
Pages
528–536
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

A relationship was detected between the frequency of infection and vitamin D level’s being

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: It is reported that deficiencies in vitamin D and zinc are associated with asthma.
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Key Findings & Data:In thisstudy we aimed to investigate the relationship between clinic findings of asthmatic children and vitaminD and zinc levels.Materials and Methods: This prospective study included a total of 149 asthmatics and 97 healthychildren with an age range of 5 to 17 years.
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Conclusion & Impact:A relationship was detected between the frequency of infection and vitamin D level’s being
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: It is reported that deficiencies in vitamin D and zinc are associated with asthma. In thisstudy we aimed to investigate the relationship between clinic findings of asthmatic children and vitaminD and zinc levels.Materials and Methods: This prospective study included a total of 149 asthmatics and 97 healthychildren with an age range of 5 to 17 years. All of the participants were evaluated for serum levels of 25 ‐hydroxyvitamin D (25(OH)D) and zinc, dietary habits, the rate of respiratory tract infections, hospitalvisits and levels of sunlight exposure.Results: Serum vitamin D and zinc levels in asthmatic children (7.7±5.29 ng/ml), (64±16.3 mcg/dl) weresignificantly lower than that in healthy children (12.3±12.87 ng/ml), (69±26.2 mcg/dl) (p< 0.015),respectively. A relationship was detected between the frequency of infection and vitamin D level’s being

Özet

Amaç: Vitamin D ve çinko eksikliğinin astım ile ilişkili olduğu bildirilmektedir. Bu çalışmada astımlı çocukların klinik bulguları ile vitamin D ve çinko düzeyleri arasındaki ilişkiyi araştırmayı istedik. Materyal ve Metot: Bu prospektif çalışmaya yaşları 5‐17 arasında değişen 149 astımlı ve 97 sağlıklı çocuk dahil edildi. Tüm katılımcıların serum 25 hidroksivitamin D (25(OH)D) ve çinko düzeyleri ölçüldü, diyet alışkanlıkları, bir yıldaki solunum yolu enfeksiyonu sıklıkları, hastane başvuruları ve güneş ışığına maruziyet süreleri sorgulandı. Bulgular: Astımlı çocukların serum D vitamini ve çinko düzeyleri sırasıyla (7,7±5,29 ng/ml), (64±16,3 mcg/dl) sağlıklı çocuklardan (12,3±12,87 ng/ml), (69±26,2 mcg/dl) belirgin şekilde düşük bulundu (p

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Cite This Article

ALTUN, D., HASKOLOĞLU, Z. Ş. (2022). Is There a Relationship between Clinical Symptoms of Asthmatic Children and Serum Levels of Vitamin D and Zinc?. Ankara Medical Journal, Cilt: 18 - Sayı: 4, 528–536. https://ajindex.com/articles/441942

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References (15)

  1. Asher I, Pearce. Global burden of asthma among children. Int J Tuberc Lung Dis 2014;18:1269–78
  2. Asher MI, Montefort S, Björkstén B et al. ISAAC Phase Three Study Group. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross‐sectional surveys. Lancet 2006;368:733–43
  3. Litonjua AA, Weiss ST. Is vitamin D deficiency to blame for the asthma epidemic? J Allergy Clin Immunol 2007;120:1031‐5
  4. Wjst M, Dold S. Genes, factor X, and allergens: What causes allergic diseases? Allergy 1999;54:757‐9
  5. Litonjua AA, Rifas‐Shiman SL, Ly NP, et al. Maternal antioxidant intake in pregnancy and wheezing illnesses at 2 y of age. Am J Clin Nutr 2006;84:903–11
  6. Nurmatov U, Devereux G, Sheikh A. Nutrients and foods for the primary prevention of asthma and allergy: Systematic review and meta‐analysis. J Allergy Clin Immunol 2011;127:724–33
  7. Devereux G, Turner SW, Craig LC et al. Low maternal vitamin E intake during pregnancy is associated with asthma in 5‐year‐old children. Am J Respir Crit Care Med 2006;174:499 –507
  8. Damera G, Fogle HW, Lim P, et al. Vitamin D inhibits growth of human airway smooth muscle cells through growth factor‐induced phosphorylation of retinoblastoma protein and checkpoint kinase 1. Br J Pharmacol 2009;158:1429–41
  9. Bozzetto S, Carraro S, Giordano G, Boner A, Baraldi E. Asthma, allergy and respiratory infections: the vitamin D hypothesis. Allergy 2012;67:10–17
  10. Ginde AA, Mansbach JM, Camargo CA Jr. Association between serum 25‐hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey. Arch Intern Med. 2009;169:384–90
  11. Black PN, Scragg R. Relationship between serum 25‐hydroxyvitamin D and pulmonary function in the third national health and nutrition examination survey. Chest 2005;128:3792–98
  12. Camargo CA Jr, Rifas‐Shiman SL, Litonjua AA, et al. Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age. Am J Clin Nutr 2007;85:788–95
  13. Ginde AA, Sutherland RE. Vitamin D in asthma: Panacea or true promise? J Allergy Clin Immunol 2010;126:59–60
  14. Brehm JM, Celedo´n JC, Soto‐Quiros ME, et al. Serum Vitamin D Levels and Markers of Severity of Childhood Asthma in Costa Rica. Am J Respir Crit Care Med 2009;179:765–71
  15. Brehm JM, Schuemann B, Fuhlbrigge AL, et al. Childhood Asthma Management Program Rese