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Journals / Akademik Gıda / 2025 / Cilt: 23 Sayı: 4

Plasma and Chemical Deposition of Polypyrrole onto MCM-41 for Glucose Sensing

Glikoz Sensörü Uygulaması İçin Polipirolün MCM-41 Üzerine Plazma ve Kimyasal Yöntemle Biriktirilmesi

Songül Şen Gürsoy(Burdur Mehmet Akif Ersoy University, Faculty of Arts and Sciences, Department of Chemistry)0000-0002-9506-9822
Barış Balıkçı(Burdur Mehmet Akif Ersoy University, Institute of Applied and Natural Sciences, Department of Chemistry)0009-0000-4396-8757
Fatih Mehmet Emen(Burdur Mehmet Akif Ersoy University, Faculty of Arts and Sciences, Department of Chemistry)
Abdulkerim Yıldız(Burdur Mehmet Akif Ersoy University, Institute of Applied and Natural Sciences, Department of Chemistry)0009-0007-0382-352X
Pages
256–266
Publication Date
2025-12-31
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Based on the Lineweaver-Burk plot, the sensor exhibited a KM value of 0.009 mM, indicating a high enzymatic affinity for glucose.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In this study, polypyrrole/MCM-41 composite was synthesized and characterized via the two different routes of chemical and plasma methods.
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Key Findings & Data:Glassy carbon electrodes were modified with MCM-41 and its respective composites through drop-casting, followed by drying, to be utilized in the amperometric sensing of glucose.
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Conclusion & Impact:Based on the Lineweaver-Burk plot, the sensor exhibited a KM value of 0.009 mM, indicating a high enzymatic affinity for glucose.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Polipirol · MCM-41 · Glikoz

Abstract

In this study, polypyrrole/MCM-41 composite was synthesized and characterized via the two different routes of chemical and plasma methods. Glassy carbon electrodes were modified with MCM-41 and its respective composites through drop-casting, followed by drying, to be utilized in the amperometric sensing of glucose. The electrode surface was modified with glucose oxidase via cross-linking. Samples were characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction analysis, thermogravimetric analysis and scanning electron microscopy (SEM) techniques. The amperometric determination of glucose was achieved onto modified working electrode at +0.70V vs. Ag/AgCl. The response time of the glucose electrodes was 30 s. In fact, the electrode modified with PPy/MCM-41-plasma exhibited analytical performance comparable to that of PPy/MCM-41-chemical. However, the PPy/MCM-41-chemical composite modified electrode exhibited the superior analytical performance towards glucose compared to the pure MCM-41 and PPy/MCM-41-plasma. The upper limit of the linear working range was 4.1 mM glucose concentration for PPy/MCM-41-chemical. The glucose sensor exhibited an analytical performance, characterized by a low detection limit (LOD) of 381 nM and a high sensitivity of approximately 910.72 µA.mM−1.cm−2. Based on the Lineweaver-Burk plot, the sensor exhibited a KM value of 0.009 mM, indicating a high enzymatic affinity for glucose.

Özet

Bu çalışmada, polipirrol/MCM-41 kompoziti kimyasal ve plazma yöntemleri olmak üzere iki farklı yolla sentezlenmiş ve karakterize edilmiştir. Camsı karbon elektrotlar, glukozun amperometrik tayininde kullanılmak üzere, MCM-41 ve ilgili kompozitleri ile damlatma ve ardından kurutma yöntemleriyle modifiye edilmiştir. Elektrot yüzeyi, glukoz oksidaz enziminin çapraz bağlama yöntemiyle tutuklanmasıyla modifiye edilmiştir. Numuneler; Fourier dönüşümlü kızılötesi spektroskopisi (FTIR), X-ışını kırınımı analizi (XRD), termogravimetrik analiz (TGA) ve taramalı elektron mikroskobu-enerji dağılımı X-ışını analizi (SEM-EDX) teknikleri ile karakterize edilmiştir. Glukozun amperometrik tayini, modifiye edilmiş çalışma elektrotu üzerinde Ag/AgCl referans elektrotuna karşı +0,70 V potansiyelde gerçekleştirilmiştir. Glukoz elektrotlarının yanıt süresi 30 saniye olarak belirlenmiştir. PPy/MCM-41-plazma- ile modifiye edilen elektrot, PPy/MCM-41-kimyasal ile kıyaslanabilir bir analitik performans sergilemiş olsa da; PPy/MCM-41-kimyasal kompozit modifiye elektrot, saf MCM-41 ve PPy/MCM-41-plazmaya kıyasla glukoza karşı üstün analitik performans göstermiştir. PPy/MCM-41-kimyasal için doğrusal çalışma aralığının üst sınırı 4,1 mM glukoz konsantrasyonu olarak saptanmıştır. Glukoz sensörü; 381 nM gibi düşük bir tayin sınırı (LOD) ve yaklaşık 910,72 µA.mM⁻¹.cm⁻²'lik yüksek bir duyarlılık ile karakterize edilen bir analitik performans sergilemiştir. Lineweaver-Burk grafiğine göre sensörün KM değeri 0,009 mM olarak hesaplanmış olup, bu değer glukoza karşı yüksek bir enzimatik ilginin göstergesidir.

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Cite This Article

Gürsoy, S. Ş., Balıkçı, B., Emen, F. M., Yıldız, A. (2025). Plasma and Chemical Deposition of Polypyrrole onto MCM-41 for Glucose Sensing. Akademik Gıda, Cilt: 23 Sayı: 4, 256–266. https://doi.org/10.24323/akademik-gida.1852482

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