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Journals / Afyon Kocatepe Üniversitesi Fen ve Mühendislik Bilimleri Dergisi / 2026 / Cilt: 26 Sayı: 5

Fabrication, Physicochemical Characterization and Antibacterial Evaluation of MgO-Modified PAN/PVP Electrospun Nanofibers

MgO ile Modifiye Edilmiş PAN/PVP Elektrospun Nanofiberlerin Üretimi, Fizikokimyasal Karakterizasyonu ve Antibakteriyel Değerlendirilmesi

Neslihan Nohut Maşlakcı(ISPARTA UNIVERSITY OF APPLIED SCIENCES, GELENDOST VOCATIONAL SCHOOL, PHARMACY SERVICES)0000-0003-1282-2477
İpek Çetinkaya(ISPARTA UNIVERSITY OF APPLIED SCIENCES, GELENDOST VOCATIONAL SCHOOL, PHARMACY SERVICES)0009-0002-6192-7996
Pages
1126–1138
Publication Date
2026-10-06
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Overall, these findings suggest that MgO-reinforced PAN/PVP nanofibers may be promising candidates for antibacterial surface materials, protective coatings, filtration media, and protective textile applications.

📌 3 Key Takeaways

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Objective & Hypothesis:Magnesium oxide (MgO)–reinforced polyacrylonitrile/poly(vinyl pyrrolidone) (PAN/PVP) nanofibers were successfully fabricated via electrospinning, and their structural, thermal, and antibacterial properties were systematically investigated.
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Key Findings & Data:Owing to its chemical stability and antibacterial properties, MgO was incorporated into the PAN/PVP matrix at loadings of 1, 3, and 5 wt% to enhance multifunctional performance.
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Conclusion & Impact:Overall, these findings suggest that MgO-reinforced PAN/PVP nanofibers may be promising candidates for antibacterial surface materials, protective coatings, filtration media, and protective textile applications.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Antibakteriyel · Magnezyum oksit · Nanofiber

Abstract

Magnesium oxide (MgO)–reinforced polyacrylonitrile/poly(vinyl pyrrolidone) (PAN/PVP) nanofibers were successfully fabricated via electrospinning, and their structural, thermal, and antibacterial properties were systematically investigated. Owing to its chemical stability and antibacterial properties, MgO was incorporated into the PAN/PVP matrix at loadings of 1, 3, and 5 wt% to enhance multifunctional performance. The effects of MgO content on fiber morphology, structure, wettability, and thermal behavior were evaluated using Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy coupled with energy-dispersive X-ray spectroscopy (SEM–EDS), water contact angle measurements (WCA), and thermogravimetric analysis (TGA). The SEM-EDS results supported the incorporation of MgO nanoparticles into the PAN/PVP nanofiber matrix and indicated the presence of Mg- and O-related signals in the MgO-containing samples. Compared to pristine PAN/PVP nanofibers, MgO incorporation resulted in higher residual mass. Uniform, bead-free nanofibers with consistent diameters were obtained from a 15 wt% PAN/PVP solution containing 5 wt% MgO. In in vitro antibacterial tests, samples loaded with 5% weight MgO were found to show measurable inhibition against Staphylococcus aureus; the inhibition zone diameters were measured as 17±0 mm and 21±0.5 mm for 10PAN/PVP/5MgO and 15PAN/PVP/5MgO, respectively. Overall, these findings suggest that MgO-reinforced PAN/PVP nanofibers may be promising candidates for antibacterial surface materials, protective coatings, filtration media, and protective textile applications.

Özet

Magnezyum oksit (MgO) ile güçlendirilmiş poliakrilonitril/poli(vinil pirolidon) (PAN/PVP) nanolifler, elektro eğirme yöntemiyle başarıyla üretildi ve yapısal, termal ve antibakteriyel özellikleri sistematik olarak incelendi. Kimyasal kararlılığı ve antibakteriyel özellikleri nedeniyle MgO, çok fonksiyonlu performansı artırmak amacıyla %1, %3 ve %5 ağırlık oranlarında PAN/PVP matrisine dahil edildi. MgO içeriğinin lif morfolojisi, yapısı, ıslatılabilirliği ve termal davranışı üzerindeki etkileri, Fourier dönüşümlü kızılötesi spektroskopisi (FTIR), taramalı elektron mikroskobu-enerji dağılımlı X-ışını spektroskopi (SEM-EDS), su temas açısı ölçümleri (WCA) ve termogravimetrik analiz (TGA) kullanılarak değerlendirildi. SEM-EDS sonuçları, MgO nanopartiküllerinin PAN/PVP nanofiber matrisine dahil edildiğini destekledi ve MgO içeren numunelerde Mg ve O ile ilgili sinyallerin varlığını gösterdi. Saf PAN/PVP nanofiberlerine kıyasla, MgO ilavesi daha yüksek artık kütleyle sonuçlandı. %15 ağırlık oranında PAN/PVP çözeltisine %5 ağırlık oranında MgO eklenerek, düzgün, boncuksuz ve tutarlı çaplara sahip nanolifler elde edildi. İn vitro antibakteriyel testlerde, %5 ağırlık oranında MgO yüklü numunelerin Staphylococcus aureus’a karşı ölçülebilir inhibisyon gösterdiği belirlenmiş; inhibisyon bölgesi çapları 10PAN/PVP/5MgO ve 15PAN/PVP/5MgO için sırasıyla 17±0 mm ve 21±0,5 mm olarak ölçülmüştür. Genel olarak, bu bulgular MgO ile güçlendirilmiş PAN/PVP nanoliflerinin özellikle antibakteriyel yüzey malzemeleri, koruyucu kaplamalar, filtrasyon ortamları ve koruyucu tekstil uygulamaları için umut vadeden adaylar olabileceğini göstermektedir.

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Cite This Article

Maşlakcı, N. N., Çetinkaya, İ. (2026). Fabrication, Physicochemical Characterization and Antibacterial Evaluation of MgO-Modified PAN/PVP Electrospun Nanofibers. Afyon Kocatepe Üniversitesi Fen ve Mühendislik Bilimleri Dergisi, Cilt: 26 Sayı: 5, 1126–1138. https://doi.org/10.35414/akufemubid.1910870

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