AI Summary & Key Takeaways
AI InsightWe tried to evaluate the role of chemotherapy in the treatment of MTK using our chemotherapy results obtained from two different patients, with the diagnosis of sporadic MTK and MEN 2B MTK, to whom we had to use chemotherapy due to the rapid progression of their diseases.
📌 3 Key Takeaways
Abstract
Medullary thyroid carcinomas (MTC) constitute 5-10 % of all thyroid cancers. Total thyroidectomy and lymph node dissection are the proposed treatment options, while external radiotherapy, radionuclide treatment and chemotherapy are reported to be useful for palliative purposes. Noncurative chemotherapy regimens are generally used in progressive medullary thyroid carcinoma cases. We tried to evaluate the role of chemotherapy in the treatment of MTK using our chemotherapy results obtained from two different patients, with the diagnosis of sporadic MTK and MEN 2B MTK, to whom we had to use chemotherapy due to the rapid progression of their diseases.
Özet
Medüller tiroid kanserleri (MTK) tüm tiroid kanserlerinin %5-10'unu oluşturmaktadır. MTK'lerinin tedavisinde total tiroidektomi ve lenf nodu diseksiyonu önerilmekte, eksternal radyoterapi, radyonüklid tedavi ve kemoterapinin palyatif amaçlı kullanılabileceği bildirilmektedir. Küratif olmayan kemoterapi rejimleri progresif MTK'ler için kullanılmaktadırlar. Hızlı progresyon nedeniyle kemoterapi uyguladığımız biri sporadik, diğeri MEN 2B MTK tanılı iki olgumuzdaki sonuçlarımızla kemoterapinin MTK'deki yerini gözden geçirmeyi amaçladık.