Journals / Uludağ Üniversitesi Tıp Fakültesi Dergisi / 2011 / Cilt: 37 - Sayı: 3

B Cell Targeted Terapies in Rheumatoid Arthritis

Romatoid Artritte B Hücre Hedefli Tedaviler

Pages
161–164
Publication Date
2011-09-01
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Biologic agents starting with tumor necrosis factor alpha inhibitors and in recent years, B cell targeted therapies opened a new era in the treatment of patients with RA.

📌 3 Key Takeaways

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Objective & Hypothesis:Rheumatoid arthritis (RA), is a chronic, systemic, inflammatory disease with usually symetric polyarticular involvement.
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Key Findings & Data:In term of inade-quate therapies it leads to substantial morbidity and mortality.
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Conclusion & Impact:Biologic agents starting with tumor necrosis factor alpha inhibitors and in recent years, B cell targeted therapies opened a new era in the treatment of patients with RA.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Romatoid Artrit. Rituksimab. Ocralizumab. Ofatumumab. B lenfosit · Rheumatoid Arthritis. Rituksimab. Ocralizumab. Ofatumumab. B lymphocyte

Abstract

Rheumatoid arthritis (RA), is a chronic, systemic, inflammatory disease with usually symetric polyarticular involvement. In term of inade-quate therapies it leads to substantial morbidity and mortality. Last ten years, there are great developments in the etiopathogenesis and treat-ment of RA. Biologic agents starting with tumor necrosis factor alpha inhibitors and in recent years, B cell targeted therapies opened a new era in the treatment of patients with RA.

Özet

Romatoid artrit (RA), sıklıkla simetrik poliartikuler tutulumla karakterize kronik, sistemik, inflamatuar bir hastalıktır. Uygun tedavi edilme-diği takdirde önemli ölçüde morbidite ve mortaliteye neden olabilir. Son on yılda RA etyopatogenezi ve tedavisinde büyük gelişmeler ya-şanmıştır. Tümör nekroz faktör alfa inhibitörleriyle başlayan biyolojik ajanlar ve yakın geçmişte B hücre hedefleyen ajanların kullanımı RA tedavisinde yeni bir çağ açmıştır.

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Cite This Article

DALKILIÇ, E., ALKIŞ, N. (2011). B Cell Targeted Terapies in Rheumatoid Arthritis. Uludağ Üniversitesi Tıp Fakültesi Dergisi, Cilt: 37 - Sayı: 3, 161–164. https://ajindex.com/articles/135039

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