Journals / Uludağ Üniversitesi Tıp Fakültesi Dergisi / 2011 / Cilt: 37 - Sayı: 3

How To Use Targeted Drugs in Metastatic Renal Cell Cancer

Metastatik Renal Hücreli Kanserde Hedefe Yönelik İlaçları Nasıl Kullanalım?

Pages
165–168
Publication Date
2011-09-01
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therefore, early determination of adverse effects that are associated with treatment and direction of treatment will improve patient's quality of life and unnecessary dose reduction won't occur.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In Renal cell cancer biology (RCC), with vascular endothelial growth factor and diagnosing of mammalian target of rapamycin B pathway, new options (targeted drugs) are developed in therapy.
📊
Key Findings & Data:With Targeted Drugs, new period started now in the RCC treatment which has limited treatment option at one time.
💡
Conclusion & Impact:Therefore, early determination of adverse effects that are associated with treatment and direction of treatment will improve patient's quality of life and unnecessary dose reduction won't occur.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Hedefe Yönelik İlaçlar. Renal Hücreli Karsinom · Targeted Therapy · Metastasis

Abstract

In Renal cell cancer biology (RCC), with vascular endothelial growth factor and diagnosing of mammalian target of rapamycin B pathway, new options (targeted drugs) are developed in therapy. With Targeted Drugs, new period started now in the RCC treatment which has limited treatment option at one time. Then bevasizumab, temsirolimus, everolimus and pazopanib were added to workings that initially started with sunitinib and sorafenib. Although antitumoral effects of drugs are similar in these treatment options, differences are seen in clinical effects and toxicity. Therefore, early determination of adverse effects that are associated with treatment and direction of treatment will improve patient's quality of life and unnecessary dose reduction won't occur.

Özet

Renal hücreli kanser (RCC) biyolojisinde vasküler endotelyal growth faktör ve mammalian target of rapamycin B yolağının tanımlanması ile tedavide yeni seçenekler geliştirilmiştir. Bu yeni seçenekler (hedefe yönelik ilaçlar) ile birlikte, bir zamanlar sınırlı tedavi seçeneği olan RCC tedavisinde artık yeni bir dönem başlamıştır. Başlangıçta sunitinib ve sorafenib ile başlayan çalışmalara daha sonra bevasizumab, temsiroli-mus, everolimus ve pazopanib eklenmiştir. Hedefe yönelik ilaçların antitümoral etkileri benzer olsada klinik etki ve toksisitede farklılıklar vardır. Bu nedenle tedavi ile ilişkili yan etkilerin erken saptanması ve tedavinin yönlendirilmesi hastanın yaşam kalitesini artıracak, gereksiz doz redüksiyonları olmayacaktır.

🔖

Cite This Article

AVCI, N., MANAVOĞLU, O. (2011). How To Use Targeted Drugs in Metastatic Renal Cell Cancer. Uludağ Üniversitesi Tıp Fakültesi Dergisi, Cilt: 37 - Sayı: 3, 165–168. https://ajindex.com/articles/135014

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...