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Journals / Uludağ Üniversitesi Tıp Fakültesi Dergisi / 2019 / Cilt: 45 - Sayı: 2

Usage of Absolute Neutrophil Count (ANC) as A Predictor for Acute Bacterial Tonsillitis in Adult Patients

Erişkin Hastalarda Akut Bakteriyel Tonsillit Tanısını Öngörmede Mutlak Nötrofil Sayısının (MNS) Kullanımı

Murat Sertan ŞAHİN
Ömer Afşın ÖZMEN
Pages
145–149
Publication Date
2019-08-01
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this sense, patients with high ANC can be treated with antibiotics without waiting for culture results.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Tonsillitis is a very common disease all over the world and it can be confusing to detect if it has bacterial or viral origin.
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Key Findings & Data:In this study, it was aimed to investigate if absolute neutrophil count (ANC) can be used as a predictor to display acute bacterial tosillitis.42 patients with the complaints of sore throat, fever and odynophagia were examined by the physician between May 2015 and May 2016.
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Conclusion & Impact:In this sense, patients with high ANC can be treated with antibiotics without waiting for culture results.
🔬Design:Research Article
📍Scope:2015 Verileri
⚙️Variables:Mutlak nötrofil sayısı · prediktör · boğaz kültürü

Abstract

Tonsillitis is a very common disease all over the world and it can be confusing to detect if it has bacterial or viral origin. In this study, it was aimed to investigate if absolute neutrophil count (ANC) can be used as a predictor to display acute bacterial tosillitis.42 patients with the complaints of sore throat, fever and odynophagia were examined by the physician between May 2015 and May 2016. Supporting blood tests and throat cultures were performed and ANC was calculated for all patients individually before the initiaiton of treatment. White blood cell count (WBCC) and ANC were significantly higher in 26 patients with positive throat culture (p<0.001). Moreover, it was detected that ANC ≥ 6.82 was able to predict positive culture results with %92.3 sensitivity and %93.7 specificity which was also statistically significant (p<0.001).According to this, ANC can be used as an easy, fast and reliable predictor for acute bacterial tonsillitis with high sensitivity and specifity. In this sense, patients with high ANC can be treated with antibiotics without waiting for culture results.

Özet

Tonsillit; tüm dünyada en sık görülen hastalıklardan olup, hastalığın bakteriyel veya viral kökenli olduğunu saptamak kimi zaman çok zor olabilir. Bu çalışmada, ‘’Mutlak Nötrofil Sayısının (MNS)’’ akut bakteriyel tonsillit tanısını öngörmede prediktör olarak kullanılıp kullanılamayacağı araştırılmak istenmiştir. Çalışma Mayıs 2015- Mayıs 2016 tarihleri arasında boğaz ağrısı, ateş ve odinofaji şikayetleri ile değerlendirilen 42 hasta üzerinden yürütülmüştür. Kan testleri ve boğaz kültürleri uygulanmış ve MNS her hasta için tedavi başlamadan önce hesaplanmıştır. Lökosit sayısı ve MNS, pozitif boğaz kültürü olan 26 hastada istatistiksel olarak anlamlı şekilde yüksek bulunmuştur(p<0,001). Buna ek olarak; MNS≥6.82 olması %92.3 sensitivite ve %93.7 spesifite ile pozitif boğaz kültürü sonuçlarının varlığını istatistiksel olarak anlamlı olacak şekilde öngörmüştür(p<0,001). Bu bilgiler ışığında MNS’ nin kolay uygulanabilir, hızlı ve güvenilir bir prediktör olarak akut bakteriyel tonsillit tanısında yüksek sensitivite ve spesifite ile kullanılabileceği ve yüksek MNS düzeyi olan hastalara boğaz kültürü sonucu beklenmeden antibiyotik tedavisinin başlanması önerilmektedir.

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Cite This Article

ŞAHİN, M. S., ÖZMEN, Ö. A. (2019). Usage of Absolute Neutrophil Count (ANC) as A Predictor for Acute Bacterial Tonsillitis in Adult Patients. Uludağ Üniversitesi Tıp Fakültesi Dergisi, Cilt: 45 - Sayı: 2, 145–149. https://ajindex.com/articles/134828

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References (15)

  1. McLafferty E, Hendry C, Farley A. The lymphatic system. Nurs Stand 2013;27(17):37-42
  2. Bathala S, Eccles R. A review on the mechanism of sore throat in tonsillitis. J Laryngol Otol 2013;127(3):227–32
  3. Shulman ST, Bisno AL, Clegg HW et al. Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America. Clin Infect Dis 2012;55:1279–82
  4. Group ESTG, Pelucchi C, Grigoryan L Guideline for the management of acute sore throat. Clin Microbiol Infect 2012;18:1–28
  5. Chiappini E, Regoli M, Bonsignori F et al. Analysis of different recommendations from international guidelines for the management of acute pharyngitis in adults and children. Clin Ther 2011;33:48–58
  6. Windfuhr JP, Toepfner N, Steffen G, Waldfahrer F, Berner R. Clinical practice guideline: tonsillitis I. Diagnostics and nonsurgical management. Eur Arch Otorhinolaryngol 2016;273(4):973-87
  7. Vicedomini D, Lalinga G, Lugli N, D’Avino A. [Diagnosis and management of acute pharyngotonsillitis in the primary care pediatrician’s office]. [Article in Italian]. Minerva Pediatr 2014;66:69–76
  8. C. Galer, E. Holbrook, J. Treves, et al. Grisel’s syndrome: a case report and review of the literature, Int. J. Pediatr. Otorhinolaryngol 2005;69:1689–92
  9. K. Ungkanont, R.F. Yellon, J.L. Weissman, et al. Head and neck space infections in infants and children, Otolaryngol. Head Neck Surg 1995;112:375–82
  10. Aalbers J, O'Brien KK, Chan WS, et al. Predicting streptococcal pharyngitis in adults in primary care: a systematic review of the diagnostic accuracy of symptoms and signs and validation of the Centor score. BMC Med 2011;9:67
  11. Fine AM, Nizet V, Mandl KD. Large-scale validation of the Centor and McIsaac scores to predict group A streptococcal pharyngitis. Arch Intern Med 2012;172:847-52
  12. Saengcharoen W, Jaisawang P, Udomcharoensab P, Buathong K, Lerkiatbundit S. Appropriateness of diagnosis of streptococcal pharyngitis among Thai community pharmacists according to the Centor criteria. Int J Clin Pharm 2016;38:1318-25
  13. A. Mantovani, M.A. Cassatella, C. Costantini, S. Jaillon, Neutrophils in the activation and regulation of innate and adaptive immunity, Nat. Rev. Immunol 2011;11:519–31
  14. B. Amulic, C. Cazalet, G.L. Hayes, K.D. Metzler, A. Zychlinsky, Neutrophil function: from mechanisms to disease, Annu. Rev. Immunol 2012;30:459– 89
  15. Bachur RG, Dayan PS, Dudley NC, et al. The Influence of Age o