Journals / Uludağ Üniversitesi Tıp Fakültesi Dergisi / 2017 / Cilt: 43 - Sayı: 3

Diagnostic Value of EBUS-TBNA in Patients with Suspicion of Sarcoidosis: Retrospective Case Series

Sarkoidoz Şüphesi Olan Olgularda EBUS-TBİA Tanı Değeri: Retrospektif Olgu Serisi

Pages
109–115
Publication Date
2017-09-01
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In addition to cytopathologic assessment, mycobacterial culture examination is playing a crucial role in differential diagnosis of granulomatous lymphadenitis.

📌 3 Key Takeaways

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Objective & Hypothesis:We aimed the determine to diagnostic value and efficacy of endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) in suspicion of pulmonary sarcoidosis.
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Key Findings & Data:We retrospectively analyzed 23 patients who underwent EBUS-TBNA for evaluation of sarcoidosis with enlarged hilar and/or mediastinal lymph nodes on thoracic competed tomography (CT) during the period of May 2016 to February 2017.
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Conclusion & Impact:In addition to cytopathologic assessment, mycobacterial culture examination is playing a crucial role in differential diagnosis of granulomatous lymphadenitis.
🔬Design:Research Article
📍Scope:2016 Verileri
⚙️Variables:Sarkoidoz. Tüberküloz lenfadenit. EBUS-TBİA. Granülomatöz lenfadenit. Tanı oranı · Sarcoidosis. Tuberculous lymphadenitis. EBUS-TBNA. Granulomatous lymphadenitis. Diagnostic rate

Abstract

We aimed the determine to diagnostic value and efficacy of endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) in suspicion of pulmonary sarcoidosis. We retrospectively analyzed 23 patients who underwent EBUS-TBNA for evaluation of sarcoidosis with enlarged hilar and/or mediastinal lymph nodes on thoracic competed tomography (CT) during the period of May 2016 to February 2017. In addition to cytologic examination, all of the patients EBUS-TBNA samples were also sent for mycobacterial cultures. Mean age of the patients was 43±14 and, 13 of them were female. Seventeen of 23 patients had a final diagnosis of sarcoidosis. One patient was ultimately diagnosed with tuberculous lymphadenitis and another one diagnosed with Mycobacterium other than tuberculous -M. avium ssp- infection. Diagnostic accuracy of EBUS-TBNA was 91.3%, and the rate of sarcoidosis was 94.4% in patients with granulomatous lymphadenitis. EBUS-TBNA is a safe and effective procedure in the assessment of patients with suspected benign hilar/mediastinal lymphadenitis. In addition to cytopathologic assessment, mycobacterial culture examination is playing a crucial role in differential diagnosis of granulomatous lymphadenitis.

Özet

Bu çalışmada, pulmoner sarkoidoz şüphesiyle endobronşial ultrason kılavuzluğunda transbronşial iğne aspirasyon (EBUS-TBİA) yapılan olgularda EBUS-TBİA tanı değeri ve etkinliğinin incelenmesi hedeflendi. Mayıs 2016- Şubat 2017 döneminde toraks bilgisayarlı tomografide (BT) büyük hiler/mediastinal lenf nodları olan ve sarkoidoz ön tanısıyla EBUS-TBİA yapılan 23 hastanın verileri retrospektif incelendi. Tüm örnekler, sitolojik incelemeye ek olarak mikobakteriyel kültür için de laboratuvara gönderildi. Yaş ortalaması 43±14 ve olguların 13ü kadın idi. Yirmiüç olgunun 17si sarkoidoz, bir hasta tüberküloz lenfadenit, bir diğeri de tüberküloz dışı mikobakteri -M. avium ssp- tanısı aldı. EBUS-TBİA tanı doğruluğu %91.3 ve granülomatöz lenfadenit saptanan olgularda sarkoidoz tanı oranı ise %94.4 bulundu. Benign mediastinal/hiler lenf nodu şüphesiyle yapılan EBUS-TBİA, etkili ve güvenli bir yöntem olarak değerlendirildi. Sitolojik değerlendirmeye ek olarak yapılacak mikobakteriyel kültür inceleme, granülomatöz lenfadenit ayırıcı tanısında kritik rol oynamaktadır.

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Cite This Article

ÇETİNOĞLU, E. D., URSAVAŞ, A., GÜÇLÜ, Ö. A., COŞKUN, F., DİLEKTAŞLI, A. G., YERCİ, Ö., ÖZAKIN, C., KARADAĞ, M. (2017). Diagnostic Value of EBUS-TBNA in Patients with Suspicion of Sarcoidosis: Retrospective Case Series. Uludağ Üniversitesi Tıp Fakültesi Dergisi, Cilt: 43 - Sayı: 3, 109–115. https://ajindex.com/articles/134785

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